Award Data

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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until June, 2020.

  1. Self expanding hydrogel for pelvic brachytherapy a novel method for vaginal packing and customized radiation therapy

    SBC: BrachyFoam, LLC            Topic: 102

    This proposal aims to develop a polymer hydrogel strategy that can be used to improve the clinical care of patients receiving brachytherapy for gynecological cancers The biocompatible hydrogel will form in situ after being injected into the vaginal space and later removed by instillation of water to soften the hydrogel for easy extraction This Phase I proposal focuses on optimizing the polymer ...

    STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  2. Therapeutic disruption of Connexin mediated microtubule regulation to target glioblastoma cancer stem cells

    SBC: Acomhal Research, Inc.            Topic: 100

    Project Summary Glioblastoma GBM is one of the most lethal incurable human diseases Even with aggressive therapies including surgical resection followed by radiotherapy and chemotherapy using temozolomide TMZ the median survival for GBM patients is only months In fact GBM cancer cells are highly infiltrative and comprise a sub population of glioma stem cells GSCs with tumorigenic pro ...

    STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  3. GRIM for head and neck cancer therapy

    SBC: GlycoMantra Inc.            Topic: 102

    Project Summary Many clinical and preclinical studies demonstrated that interferons IFNs exert a superior anti tumor effect when combined with retinoids a class of vitamin A metabolites We identified a novel tumor suppressor Gene associated with Retinoid IFN induced Mortality GRIM by a genome wide knockdown strategy In our recent publication in the PNAS we have shown that GRIM g ...

    STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  4. Knowledge and Usage of Lactation using Education and Advice from Support Network KULEA NET

    SBC: Benten Technologies, Inc.            Topic: NIMHD

    PROJECT SUMMARY ABSTRACT Breastfeeding has the potential to reduce health disparities associated with infant mortality and morbidity Breastfeeding rates by ethnicity in the United States show a marked disparity in African American AA women as compared to other groups Barriers to breastfeeding are complex with literature citing a lack of knowledge poor family and social support inhibiting soc ...

    STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  5. Lipid Enhanced Nano Sensors LENS for lead and mercury detection in water

    SBC: ZANSORS            Topic: NIEHS

    Abstract This Phase I application aims to determine the feasibility of using lipid enhanced nanosensor LENS arrays for smart phone based detection of lead Pb and mercury Hg in drinking water at concentrations above FDA allowable levels LENS arrays are composed of fluid lipid multilayer diffraction gratings on surfaces The fluid nature of these arrays has two advantages reagents can ...

    STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  6. Biocatalytic production of precursors to lutein and zeaxanthin to address age related macular degeneration

    SBC: EscaZyme Biochemicals, LLC            Topic: N

    Project Summary Atrophic dry age related macular degeneration AMD is the leading cause of severe loss of vision for those over age Dietary supplements containing lutein and zeaxanthin are recommended by the NEI for those at risk of late AMD There has been a corresponding growth in demand for these two xanthophylls Lutein and zeaxanthin are currently sourced from marigolds grown mostl ...

    STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  7. Development lightmap rendering technology to advance infrared simulation capabilities for training applications

    SBC: JRM Enterprises, Inc.            Topic: AF17AT012

    JRM Technologies proposes a new CUDA-based 3D thermal signature physics engine which combines real-time raytracing (photon-mapping) and localized temperature maps that together with new GPU shaders will better model the transient interactive coupling of dynamic thermal sources with affected 3D scene elements. To support this new physics engine, JRM proposes to leverage and extend its proven real- ...

    STTR Phase I 2017 Department of DefenseAir Force
  8. High Strain Composite Testing Methodologies

    SBC: MC Technologies LLC            Topic: AF17AT019

    An innovative loading stage design based on the principle of eccentric loading is proposed for mechanical testing of thin composites to impart precise mixtures uniaxial and bending stresses. In contrast to alternative designs, the mechanism is fully compatible with advanced experimental techniques such as three-dimensional digital image correlation (3D-DIC) strain measurements and in situ micro X- ...

    STTR Phase I 2017 Department of DefenseAir Force
  9. Bayesian Inference of Spacecraft Geometry and Pose

    SBC: VISION SYSTEMS INC.            Topic: AF17AT007

    Space platforms are complex dynamical systems and there are many reasons to model them from ground telescope imagery as well as from space-based sensor platforms. One key motivation is to determine the operational state and configuration of the vehicle. Key questions such as did the solar panels fail to deploy, did the object begin to tumble unexpectedly may be addressed by a sufficiently detaile ...

    STTR Phase I 2017 Department of DefenseAir Force
  10. Balloon-Based Disturbance Measurements in the Upper Atmosphere

    SBC: Tao Of Systems Integration Inc            Topic: AF16AT02

    For prediction of hypersonic aerothermodynamics, knowledge of the relevant disturbance levels is required to determine transition locations in flight at the altitudes of interest. Tao Systems and University of Maryland (UMD) propose to develop a flight platform and measurement system capable of acquiring pressure, temperature, density, velocity fluctuations, and particulates using a miniaturized, ...

    STTR Phase I 2017 Department of DefenseAir Force
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