Award Data

ABSTRACT: MicroLink and its collaborators, Rochester Institute of Technology and Magnolia Solar, will develop a high-efficiency, single-junction, epitaxial lift-off (ELO) GaAs solar cell by incorporating nano-scale features, such as quantum dots and optically functional textures, within the solar cell structure. The principal technical objective of the project is to increase the AM0 efficiency o ...

ABSTRACT: CU Aerospace (CUA) and team partner the University of Illinois at Urbana-Champaign (UIUC) propose to perform research, development and demonstration of experimental quenching free measurements of heat-release in a realistic highly turbulent plasma-assisted flame. Kinetics models will be correspondingly updated and detailed 3D multiphysics simulations will be validated by the measuremen ...

ABSTRACT: Living systems rely on pervasive vascular networks to enable a plurality of biological function, exemplified by natural composite structures that are lightweight, high-strength, and capable of mass and energy transport. In contrast, synthetic composites possess high strength-to-weight ratios but lack the dynamic functionality of their natural counterparts. CU Aerospace, with team partne ...

ABSTRACT: The objective of this project is to move an energy efficient process for the conversion of carbon dioxide and water into syngas, a key feedstock for the production of synthetic chemicals. BENEFIT: If we are successful we will have a new process to convert air water and sunlight into transportation fuels. That will result in a domestic source of fuels that does not compete with the foo ...

DESCRIPTION (provided by applicant): AuraSense Therapeutics (AST), along with Northwestern University, is applying a recently developed technology using oligonucleotide-functionalized nanoparticles (called spherical nucleic acids or SNAs) to control protein expression. These easily synthesized nanoparticles can have either DNA or RNA shells, and are less than 50 nm in hydrodynamic diameter. SNA co ...

Project Summary The goal of this STTR grant application is to engineer powerful NK cell-based cytolytic effector cells for therapeutic applications. The cells will combine the selectivity and specificity of T cells and the ability of NK cells to mediate effective cytolytic activity against a wide spectrum of aberrant cells, including those with impaired adhesion properties. To achieve this goal we ...

DESCRIPTION (provided by applicant): Genomic instability is a hallmark of cancer, yet is underdeveloped as a therapeutic target area The central goal of this program is to develop new cancer therapeutics that target genomic instability as a hallmark of cancer cells, bringing new, cancer-cell selective treatments to the clinical oncology market. Two key challenges in current cancer therapy are mini ...

Abstract Septicemia poses a major health care challenge. Modern therapies requiring suppression of patients' immune systems, a growing numbers of elderly people in the population, and the emergence of drug-resistant bacteria, have increased the prevalenceand severity of the disease over the past few decades. Current treatments rely on drugs that do not significant reduce morbidity and mortali ...

ABSTRACT: CU Aerospace (CUA) and team partner the University of Illinois at Urbana-Champaign (UIUC) propose to perform research, development and demonstration of experimental quenching free measurements of heat-release in a realistic highly turbulent plasma-assisted flame. Kinetics models will be correspondingly updated and detailed 3D multiphysics simulations will be validated by the measurements ...

ABSTRACT: Sierra Engineering Inc. (Sierra) believes that existing chemical kinetic models can be efficiently incorporated into commercial CFD codes to predict the mixing, pyrolysis, soot formation and carbon deposition within film cooled rocket engines. During this Phase I STTR effort we will demonstrate that this analysis capability is practical and that we can generate appropriate model validati ...