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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. A Novel Approach to Purifying iPSC Derived Cell Cultures

    SBC: HocusLocus Inc.            Topic: 200

    DESCRIPTION provided by applicant We are pioneering an RNA based switch technology called structurally interacting RNAs sxRNA which utilizes post transcriptional gene regulation as a reporter for miRNA detection Normally RNA binding proteins RBP associate with a andapos stem loop structure to facilitate translation of an upstream coding region by as much as an order of magnitude It is ...

    STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
  2. Continuing Care App for Probationers and Parolees with Substance Use Disorders

    SBC: COG ANALYTICS, LLC            Topic: NIMHD

    DESCRIPTION provided by applicant Substance use disorders SUDs continue to be one of the most serious public health problems in the US Studies have consistently documented a substantially higher prevalence of SUDs among individuals under criminal justice supervision At year end approximately million adults were on probation or parole in adults African American probationer ...

    STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
  3. Avatar Assisted Therapy for Probationers and Parolees with Substance Use Disorders

    SBC: COG ANALYTICS, LLC            Topic: 102

    DESCRIPTION provided by applicant Substance use disorders SUDs continue to be one of the most serious public health problems in the US Studies have consistently documented a substantially higher prevalence of SUDs among individuals under criminal justice supervision At year end approximately million adults were under criminal justice supervision in the US of which million i ...

    STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
  4. Electronic Optimization of Stem Cell Derived Human Cardiac Myocytes

    SBC: Cytocybernetics Inc            Topic: NHLBI

    DESCRIPTION provided by applicant As part of the FDA approval process for novel therapeutic drugs safety screening demonstrating that the new drug does not have deleterious effects on the human cardiac action potential is required Healthy human heart cells are not available for such preclinical drug testing There is currently no consensus on the best experimental approach to provide the most ...

    STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
  5. Evaluation of TRB-N0224, a Proprietary Chemically Modified Curcumin, for the Treatment of Periodontal Disease in a LPS-Induced Rat Model

    SBC: TRAVERSE BIOSCIENCES, INC.            Topic: NIDCR

    DESCRIPTION provided by applicant Traverse Biosciences Inc is a pre clinical stage drug development company working to commercialize new chemical entities which act to resolve inflammatory conditions through pleiotropic host modulation of pathologically unrestrained matrix metalloproteinases MMPs and pro inflammatory cytokines The companyandapos s lead drug candidate TRB N is a propri ...

    STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
  6. Speech Enhancement Based on Auditory Coding of Voiced Signals

    SBC: OMNISPEECH, LLC            Topic: NIDCD

    DESCRIPTION provided by applicant The greatest challenge to auditory communication is background noise especially in the complex acoustic environments that are experienced in daily life This project proposes to develop a novel speech enhancement algorithm that is robust in the presence of everyday environmental interference The algorithm is inspired by recent findings related to the neural c ...

    STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
  7. Development of a high-throughput assay for measuring m6A demethylase activity

    SBC: Base5 Biosciences Inc            Topic: NIDA

    DESCRIPTION provided by applicant N methyladenosine m A was recently discovered to be a widespread base modification present in thousands of mammalian mRNAs In addition to its prevalence throughout the transcriptome researchers have also revealed that m A is a reversible modification suggesting that dynamic regulation of mRNA methylation is a novel and widespread RNA regulatory mechanism ...

    STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
  8. Technology-Guided Opioid Cessation for Post-Operative Pain

    SBC: MedicaSafe Inc            Topic: R41

    DESCRIPTION provided by applicant This STTR application proposes development of MedicaSafe Inc andapos s Multimodal Analgesic Protection System MAPSafe Built around MedicaSafeandapos s proprietary Medication Therapy Optimization MTO technology MAPSafe will be designed to mitigate the myriad risks associated with prescription opioid use post operatively and throughout recovery after surge ...

    STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
  9. Mass Spectrometric Screening of the Effect of Chemical Toxicants on the Human Epitranscriptome during Stem Cell Differentiation

    SBC: ATHGHIN BIOTECHNOLOGY, INC.            Topic: 113

    DESCRIPTION provided by applicant Epitranscriptomics explores levels and evolution of RNA modifications as a response from intra and inter cellular stimuli These modifications and the levels at which they are present are emerging as important regulators of biological processes Perturbations such as chemical toxicants exposure can alter the patterns of specific modifications on RNA sub types ...

    STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
  10. The Development of a High-Throughput Assay to Screen Chemical Compounds in Human Pluripotent Stem Cell Derived Neural Cells

    SBC: ATHGHIN BIOTECHNOLOGY, INC.            Topic: 113

    DESCRIPTION provided by applicant The long term objective of this application is to provide a high throughput platform to test the effects of chemical exposure on human brain development In the US chemicals are not required for health or environmental safety testing before their incorporation in consumer products Over registered chemicals are in commerce most of which are used withou ...

    STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
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