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Award Data
The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.
Download all SBIR.gov award data either with award abstracts (290MB)
or without award abstracts (65MB).
A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.
The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.
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Integrated biochemical and bioinformatic technologies for accurate transcriptome-wide full-length RNA assembly.
SBC: LUCIGEN CORPORATION Topic: 172DESCRIPTION provided by applicant The human transcriptome is significantly more complex than its cognate genome due to the hundreds of thousands of possible isoforms allele specific expression issues variable RNA editing changes and differential expression patterns spanning cell types developmental stages and physiological stresses Next generation sequencing NGS platforms are fundame ...
STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health -
Measuring Bladder Permeability with MRI using a Novel Contrast Agent Formulation
SBC: Lipella Pharmaceuticals Inc. Topic: 400DESCRIPTION provided by applicant This project entails the development of a novel dual component MRI contrast agent formulation for the detecting permeability in the luminal surface of the urinary bladder The purpose of having such a test is ultimately to allow clinicians in certain circumstances to differentially diagnose a chronic non infectious inflammation of the urinary bladder from a ...
STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health -
Novel mass spectrometry methods for profiling modified RNA nucleotides in the nervous system
SBC: Ribonova Inc. Topic: NIDADESCRIPTION provided by applicant Pseudouridine is the most abundant post transcriptionally modified nucleoside found in ribonucleic acid RNA Pseudouridine is an enzymatically generated isomer of the canonical base uridine with additional hydrogen bonding capabilities and appears to lead to local structural and biochemical effects within RNAs Pseudouridine has been detected in several type ...
STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health -
Biological treatment of bacterial keratitis
SBC: AMEBAGONE INC Topic: NDESCRIPTION provided by applicant Staphylococcus is the most common cause of infections worldwide The pathogen persists asymptomatically on human skin from which it may spread to ocular tissues and cause corneal infection When this happens corneal bacterial keratitis can occur and if not treated effectively it may lead to blindness Multi Drug Resistant MDR variants of S aureus Sa are ...
STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health -
Polaris Oncology Survivor Transition POST System
SBC: POLARIS HEALTH DIRECTIONS, INC Topic: 100DESCRIPTION provided by applicant By January oncology care providers will be expected to craft Survivorship Care Plans SCPs for all individuals ending active treatment for cancer however there is a lack of systematic study of the impact survivorship planning has on patients providers or healthcare systems The Polaris Oncology Survivorship Transition POST program is a web based sy ...
STTR Phase II 2015 Department of Health and Human ServicesNational Institutes of Health -
Neuroimaging tools for presurgical brain mapping
SBC: PRISM CLINICAL IMAGING INC Topic: 102DESCRIPTION provided by applicant The goal of this project is to develop functional magnetic resonance imaging fMRI tools to assist the diagnosis and treatment of human patients with a brain tumor or other operable pathology The specific focus of this proposal is to produce a practical clinic ready suite of MR imaging methods analyses and display tools to solve the number one impediment to ...
STTR Phase II 2015 Department of Health and Human ServicesNational Institutes of Health -
mTOR Substrate Phosphorylation: A New Bioassay for Therapeutics
SBC: COGNIZANCE BIOMARKERS, LLC Topic: 107DESCRIPTION provided by applicant There are a growing number of human diseases that have been linked to abnormally enhanced activation of the mammalian target of rapamycin mTOR signaling cascade a central pathway governing eukaryotic protein synthesis These include neurodevelopmental disorders associated with epilepsy autism and intellectual disability as well as cancer obesity and dia ...
STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health -
Axonal Transport HTS Platform for Neurodegeneration Drug Discovery
SBC: Bellbrook Labs, LLC Topic: 106DESCRIPTION provided by applicant Neurodegenerative diseases that affect motor neurons such as PD ALS and HD represent an enormous unmet medical need that is growing with the aging population Existing treatments have little or no effect on the course of disease and patients have to cope with the loss of brain and body function for the rest of their lives Defects in the transport of organell ...
STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health -
Neurotrophic Agents for Treating Parkinson's Disaese
SBC: SENEB BIOSCIENCES INC Topic: 102DESCRIPTION provided by applicant Parkinsonandapos s disease PD is a neurodegenerative disorder characterized by motor function and eventually cognitive decline GM depletion is validated as a therapeutic target for Parkinsonandapos s disease PD in clinical studies in which GM replacement stabilized motor function loss and may be disease modifying However GM has poor pharmacologic prop ...
STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health -
IMMEDIATE FIT USING INNOVATIVE TECHNOLOGY TRANSTIBIAL PROSTHESIS
SBC: IFIT PROSTHETICS, LLC Topic: NIADESCRIPTION provided by applicant The goal of iFIT Prosthetics LLC r and its founder was to create and commercialize a modular immediate fit fully adjustable transtibial prosthesis system suitable for mass production using high strength polymer materials that are injection molded at a fraction of the cost of conventionally made prostheses This goal was achieved and now the aims of this P ...
STTR Phase II 2015 Department of Health and Human ServicesNational Institutes of Health