List

For best search results, use the search terms first and then apply the filters
Reset

The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until April, 2020.

  1. High Resolution Magnetoencephalography using Atomic Magnetrodes

    SBC: QUSPIN INC.            Topic: 101

    DESCRIPTION provided by applicant We propose to develop a small fully integrated ultra sensitive commercial magnetometer that will merge the multi use and cost effective attributes of present EEG electrodes with the sensitivity of SQUID sensors Our device referred to as a magnetrode will combine reliable autonomous operation with straightforward multi channel integration for a robust MEG ...

    SBIR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health
  2. Identification of the Antisickling Compounds in SCD

    SBC: INVENUX, LLC            Topic: NHLBI

    ABSTRACT Sickle cell disease SCD affects approximately people in the United States and millions worldwide Symptoms appear shortly after birth and in less developed countries the majority of children with SCD die before the age of five In the U S SCD patients suffer chronic pain and fatigue severe acute painful crises requiring hospitalization and opiates strokes and multi organ ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  3. Crossover Study of an Oral Treatment for Sickle Cell Disease

    SBC: INVENUX, LLC            Topic: NHLBI

    ABSTRACT Sickle cell disease SCD affects approximately people in the United States and millions worldwide Symptoms appear shortly after birth and in less developed countries the majority of children with SCD die before the age of five In the U S SCD patients suffer chronic pain and fatigue severe acute painful crises requiring hospitalization and opiates strokes and multi organ ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  4. Matrix free Laser Desorption and Ionization Substrates for Mass Spectroscopy

    SBC: InRedox LLC            Topic: 400

    Project Summary This multi phase SBIR project targets an important problem in life science increasing resolution and throughput of mass spectroscopy MS using inexpensive nanostructures substrates for matrix free laser desorption and ionization LDI Soft ionization techniques for MS such matrix assisted LDI MALDI have become among the most important tools in applications from proteomics ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  5. Point of Care Prognostic Tool for Sepsis

    SBC: Mbio Diagnostics, Inc.            Topic: 200

    Sepsis is a devastating cause of morbidity and mortality in intensive care units ICUs with estimates of U S incidence ranging from to million cases annually The heterogeneity of clinical presentation etiology patient history severity etc creates a major challenge for patient management and has significantly complicated development of new therapies almost all of which have f ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  6. Point of care immunoassay for rapid diagnosis of tinea capitis

    SBC: DxDiscovery Incorporated            Topic: NIBIB

    Tinea capitis scalp ringworm is a fungal dermatophyte infection of scalp hair follicles that afflicts of the U S pediatric population Tinea capitis is a major health care disparity because it occurs predominantly among individuals with a disadvantaged socioeconomic background and sub Saharan African descent Diagnosis of tinea capitis is currently dependent on culture and microscopy Both ...

    SBIR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  7. A next generation spatial light modulator for mapping of neural networks

    SBC: Boulder Nonlinear Systems, Inc.            Topic: NIBIB

    Boulder Nonlinear Systems BNS and Prof Edward Boyden s Synthetic Neurobiology Group at the Massachusetts Institute of Technology MIT Media Lab propose to develop a new liquid crystal spatial light modulator SLM capable generating high resolution holograms to overcome the imaging gap that currently divides cellular level optogenetic techniques and whole brain techniques to improve function ...

    SBIR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health
  8. Safety Studies for Clinical Trials of a Botanical Drug for Sickle Cell Disease

    SBC: INVENUX, LLC            Topic: NHLBI

    DESCRIPTION provided by applicant New therapeutic agents are urgently needed for the treatment of sickle cell disease the worldandapos s most common genetic disease Our long term goal is to develop a botanical drug SCD for use in children and adults that slows or stops disease progression Sickle cell disease affects approximately people in the United States and millions worldw ...

    SBIR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health
  9. Screening for the autoimmune component of multiple sclerosis

    SBC: Op-T-Mune, Inc            Topic: NIAID

    Multiple Sclerosis is an inflammatory neurodegenerative disease with autoimmune components that exacerbate and potentially initiate the disease Diagnosis is invasive time consuming relatively expensive and extremely difficult In fact no clear diagnostic test yet exist A major concern is that MS symptoms are identical to the symptoms of numerous other neurologic diseases OND as well as some ...

    STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  10. Development of Antimicrobial Peptides to Target Gram negative Pathogens

    SBC: Aurora Oncology, Inc.            Topic: NIAID

    The dramatic and ever increasing emergence of medically relevant strains of bacteria resistant to traditional antibiotics is now a major human health issue Antibiotic resistance has arisen due to the extensive clinical use of classical antibiotics We have now seen the development of so called Superbugs that are resistant to most or all of the available antibiotics The Infectious Diseases Soci ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health

Agency Micro-sites

SBA logo
Department of Agriculture logo
Department of Commerce logo
Department of Defense logo
Department of Education logo
Department of Energy logo
Department of Health and Human Services logo
Department of Homeland Security logo
Department of Transportation logo
Environmental Protection Agency logo
National Aeronautics and Space Administration logo
National Science Foundation logo
US Flag An Official Website of the United States Government