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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until April, 2020.

  1. Citizen-Science Technology for HealthyLiving at Home

    SBC: Access Sensor Technologies LLC            Topic: NIMHD

    Project Summary Environmental risk factors are attributable toof the chronic respiratory disease burden in the U Sand toof the burden from other non communicable diseasese gcancercardiovascular diseaseand diabetesExposure to environmental risk factors occurs through various forms of water and air pollutionwith a smaller attribution to sources like noiseradiationand physical hazardsMuch of this exp ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  2. Translating an In-Person Brief, Bystander Bullying Intervention (STAC) to a Technology-Based

    SBC: KLEIN BUENDEL, INC            Topic: 102

    Project Summary While studies support the efficacy of comprehensiveschool wide interventions in reducing bullyingthese types of programs can require significant time and financial resources for implementationresulting in barriers to providing school based bullying preventionespecially in low income and rural communitiesAdditionallyalthough training bystanders to act asdefenderson behalf of targets ...

    STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  3. Optimizing Usability of the Orally Rehydrate Children at Home Mobile Application- Optimize ORCAH

    SBC: Data2Care Technologies, LLC            Topic: NICHD

    Project Summary Abstract Acute gastroenteritisAGEinfectious diarrhea is a common condition that is costly in the US and highmortality in developing nationsThe cornerstone of AGE management is oral rehydration therapyORTan evidence based technique that has saved overmillion lives in theyears since its introductionThe problem we aim to address is ORT s underuse in developed countries specifically in ...

    STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  4. Optimization of Betulinic Acid analogs for T-type calcium channel inhibition for non-addictive relief of chronic pain

    SBC: Regulonix            Topic: NIDA

    ABSTRACT Chemotherapy induced peripheral neuropathyCIPNis a commonprevalenceand potentially doselimiting side effect of many cancer chemotherapy drug treatment regimensClinicallyCIPN presents with pain that is burningshooting or electric shock likeThe increase in prevalence of cancer coupled with an increase in the cancer survival rates due to chemotherapy regimens is transforming cancer pain into ...

    STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  5. Stable Glucagon for Treatment of Hyperinsulinism

    SBC: AMIDEBIO, LLC            Topic: 200

    In severe persistent hyperinsulinismHIrepeated hypoglycemic episodes can ultimately lead to permanent seizure disorderslearning disabilitiescerebral palsyblindness and even deathClinical studies have demonstrated the effectiveness of both short term and long term treatment with glucagon for severe forms of HI and continuous subcutaneous administration of glucagon has been recommended both because ...

    SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  6. Fixed dose analgesic combination with non-opioid mechanism to prevent opioid misuse

    SBC: Synventa LLC            Topic: NIDA

    PROJECT SUMMARYABSTRACTWith nearlymln people suffering from chronic pain in the US alone and the global market projected to reach $bln bythere is both a major unmet medical need and a significant commercial opportunityDominated by opioid drugsthis field also suffered from alarming consequences of opioid drug overuse and misuseAntagonists acting at TRPVreceptor have long been recognized as one of t ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  7. Novel formulations of Allopregnanolone to treat Alzheimer's Disease

    SBC: Proneurogen, Inc            Topic: NIA

    PROJECT SUMMARY ABSTRACT Alzheimer s diseaseADis a progressive multifactorial disease affecting more thanmillion people worldwide and is the most common dementia of late lifeTo dateno interventions have demonstrated substantial therapeutic efficacy to preventdelay or treat ADCurrent thinking in the field embraces the complexity of AD pathophysiologywhich has enabled a more diverse therapeutic pipe ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  8. Fourth Trimester- A web-based tool for Postpartum Care to Address the Needs of Underserved Women

    SBC: Orange Square Design, Inc.            Topic: NIMHD

    PROJECT SUMMARY ABSTRACT In the United Statesthe postpartum period is a critical time for both maternal and child healththe mortality rate is the highest among other developedhigh income countries and more than half of all maternal deaths occur postpartumfrom one day to one year after birthThis poor outcome is linked to the racial and ethnic disparities that disproportionately effect black women w ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  9. A Simple Blood Test for Microsatellite Instability Status

    SBC: CALVIRI, INC.            Topic: 102

    Abstract Immune checkpoint inhibitorICIimmunotherapeutics are having an important and expanding impact on the treatment of cancerAfter only a few years of clinical useICIs have become a multi billion dollar family of productsHoweveronlyof patients have a positive response to treatmentTo datethe best indicator for a positive response is the microsatellite instabilityMSIstatusIndividualsno matter wh ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  10. Development of Serious Games and Physical Activities Instructed by a Social Robot for Improving the Well-being of Elderly Individuals with Alzheimer's Disease and Dementia

    SBC: Dream Face Technologies, LLC            Topic: NIA

    The objective of the proposed direct Phase II SBIR project is to develop and study and the effectiveness of Serious Games and physical Activities played performed by elderly people with Alzheimer s disease and ADrelated Dementias in interaction with Ryanour successfully piloted Socially Assistive RobotSARRyan is an intelligent conversational life like social robotdesigned to improve the well being ...

    SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health

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