Award Data

ABSTRACT The goal of this proposal is to repurpose technology developed for Next-Gen Proteomics to develop a highly-scalable digital serotyping technology for infectious disease analysis, with particular application to influenza and Covid-19. The approach is broadly applicable and should greatly improve upon cost, sensitivity, usability, and throughput of population-level serotyping and greatly im ...

Cost-effective and minimally invasive monitoring of metastatic breast cancer (MBC) patients for disease progression or response to therapy is an unmet need in the clinical management of the disease. Imaging technologies are currently the gold standard of such monitoring. However, there is controversy regarding the type and frequency of imaging required. Imaging is expensive, time consuming, slow t ...

SUMMARY Chronic skin wounds associated with various diseasese gdiabetesand aberrant healing from acute woundinge ghypertrophic scarringare a major health care burdenThis health burden increases in aging populationsThe cost to treat these conditions exceeds $billion annuallyCurrentlyREGRANEXa cream containing a biologic based on human PDGFPlatelet Derived Growth Factoris the only FDAFood and Drug A ...

AbstractA major shortfall in clinical care for diabetes is a rapid and accurate screen for progression to diseaseCurrent criteria involve HLA haplotypeand the presence of auto antibodiesAAGenome wide associated studiesGWASrevealed only immune associated genes including HLA as T D predictorsThe ability to differentiate from other diseases was very limitedPre typediabetesp T Dis now being identified ...

Sickle cell diseaseSCDis the most common inherited blood disorder in the U Sand disproportionately affects African Americans and HispanicsApproximatelyU Schildren are born with SCD annuallySCD results from abnormal hemoglobin and causes red blood cellsRBCsto become misshapedsickle shapedSickled cells can block the flow of blood in small arteries causing tissue and organ damage and other lifethreat ...

Driving while intoxicatedDWIremains a substantial and preventable source of morbidity and mortality in the United StatesA variety of sanctions and interventions have been attempted to reduce DWI in the U Sincluding enhanced DWI enforcement effortsstricter drunk driving lawsresponsible alcohol beverage service trainingand alcohol treatmentThe Ignition Interlock DeviceIIDwhich requires a driver to b ...

Health disparities are high among LatinasThey are more likely to be overweightdiagnosed with diabetesand physically inactive compared to their non Hispanic White counterpartsThusinterventions that target improving health access and ameliorating chronic diseases among Latinas are of high public health importanceAvailable data suggest that community focused interventions produce improvements in phys ...

PROJECT SUMMARYemocha Mobile HealthInc and Johns Hopkins investigators have developed a userfriendlyHIPAA compliant application for asynchronous video directly observed therapyDOTmiDOTThe miDOT platform consists of a patientfacing mobile application where patients can recordvideos of themselves taking medication at their convenience and a providerfacing web portalthat allows providers to monitor a ...

Native American Cancer InitiativesIncNACIis a woman ownedminorityAmerican Indianbusiness with fewer than three full time equivalent employeesThis for profit companyfounded inhas the mission to provide technical assistance and products on Native Americanscultural issuesevaluationprogram development and assessment and cancer care across the continuumoutreach through end of life careto communitiespat ...

ABSTRACT Tuberculosis ranks in the top ten worldwide cause of death and now ranks ahead of HIV, making it the number one infectious disease killer. Perhaps, most alarming is the global prevalence of multidrug-resistant TB (MDR- TB) and extensively drug-resistant TB (XDR-TB): more than 5% of new TB cases are MDR-TB and 10% of these have XDR-TB. And, the number of enrolled XDR-TB cases has grown fro ...