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Award Data

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The Award database is continually updated throughout the year. As a result, data for FY20 is not expected to be complete until September, 2021.

  1. Noninvasive Neural Stimulation Technology

    SBC: HIGHLAND INSTRUMENTS            Topic: 102

    DESCRIPTION provided by applicant The past decade has seen a rapid increase in the application of brain stimulation devices to treat a variety of movement disorders such as Parkinsonandapos s disease PD and other neuropathologies Present noninvasive brain stimulation technologies suffer from fundamental limitations and have yet to reach the level of efficacy of invasive methods such as de ...

    SBIR Phase II 2013 Department of Health and Human ServicesNational Institutes of Health
  2. PillStream: Agile High-Throughput Assembly of Custom Multi-Medication Packaging

    SBC: ARTAIC, LLC            Topic: NINR

    DESCRIPTION provided by applicant Errors in the administration of medications to residents of long term care facilities LTCFs threaten resident safety and add significant unnecessary costs to the healthcare system Use of unit dose medications that require LTCF staff to manually sort and assemble specific patient medications times per day can result in error rates as high as with of total errors ha ...

    SBIR Phase II 2013 Department of Health and Human ServicesNational Institutes of Health
  3. Closed-Loop Wireless Optical Neuromodulation for Motion Disorders

    SBC: FERRO SOLUTIONS, INC.            Topic: NINDS

    DESCRIPTION provided by applicant Optogenetic tools for activating and silencing specific neurons embedded within dense brain networks in a temporally precise fashion using light are key to understanding the roles that specific neurons play in behavior neural computation and disease In our Phase I SBIR Ferro Solutions and the Boyden lab at MIT collaborated to develop a fully wirelessly powered and ...

    SBIR Phase II 2013 Department of Health and Human ServicesNational Institutes of Health
  4. Novel Antithrombotic Diadenosine Tetraphosphate Analogs

    SBC: GLSynthesis Inc.            Topic: 100

    DESCRIPTION Undesired platelet activation can be result of many common pathologies or interventions Arterial thrombosis and the acute ischemic events that follow such as myocardial infarction and stroke are among the leading causes of death incapacitation and rising health care costs in the developed world Therefore antiplatelet drugs have significant market share and clinical importance ...

    SBIR Phase II 2013 Department of Health and Human ServicesNational Institutes of Health
  5. Narrow-spectrum Agents Acting against Helicobacter pylori

    SBC: Arietis Corporation            Topic: NIAID

    DESCRIPTION provided by applicant The goal of this project is to develop a therapeutic acting specifically against Helicobacter pylori the causative agent of peptic ulcer and gastric carcinoma Roughly every other person carries the pathogen and there are an estimated cases annually of active infection in the US The currently used triple therapy is a combination of a proton pump inhibitor and broad ...

    SBIR Phase II 2013 Department of Health and Human ServicesNational Institutes of Health
  6. Long-Acting G-CSF Analog for Treating ARS

    SBC: BOLDER BIOTECHNOLOGY INC            Topic: NIAID

    DESCRIPTION provided by applicant Development of radiological nuclear medical countermeasures to treat Acute Radiation Syndrome ARS is a high priority research area for NIAID Bone marrow is one of the most sensitive tissues to radiation damage and impaired hematopoiesis is one of the first clinical signs of excessive radiation exposure often resulting i death Granulocyte colony stimulating ...

    SBIR Phase II 2013 Department of Health and Human ServicesNational Institutes of Health
  7. Drug Discovery from Slow Growing and Rare Microbial Species

    SBC: NOVOBIOTIC PHARMACEUTICALS, LLC            Topic: NIAID

    DESCRIPTION provided by applicant The overall goal of this project is to discover novel antibiotics to combat important drug resistant pathogens We are running out of treatment options for pathogens such as S aureus MRSA vancomycin resistant Enterococci VRE multidrug resistant P aeruginosa A baumannii ESBL and New Delhi metallo b lactamase producing Enterobacteriaceae and M tuberculosis Only novel ...

    SBIR Phase II 2013 Department of Health and Human ServicesNational Institutes of Health
  8. Tribosupplementation of Injured Joints

    SBC: TRIBOLOGICS, LLC            Topic: NIAMS

    DESCRIPTION (provided by applicant): Joint injury is a well established risk factor in the pathogenesis of post-traumatic osteoarthritis (PTOA). In particular, patients with meniscal tears are at high risk for early PTOA. Chondroprotection of the joint surface is mediated by lubricin, a large glycoprotien which forms a lubricating nanofilm on the cartilage surface and provides anti-adhesion via st ...

    STTR Phase II 2013 Department of Health and Human ServicesNational Institutes of Health
  9. Developmental Disabilities Dentistry Online

    SBC: Praxis            Topic: NIDCR

    DESCRIPTION (provided by applicant): Individuals with intellectual and developmental disabilities (I/DD) have more untreated caries and a higher prevalence of gingivitis and other periodontal diseases than the general population (NIDCR, 2009). In order to address this health care disparity, more dentists are needed who understand and are trained to meet the needs of this population. Few in-depth ...

    STTR Phase II 2013 Department of Health and Human ServicesNational Institutes of Health
  10. Structure guided rational engineering of novel DNA reagents.

    SBC: NEW ENGLAND BIOLABS, INC.            Topic: NIGMS

    DESCRIPTION (provided by applicant): Type II restriction enzymes (REases) are indispensible tools of modern medical research. It has long been a goal of REase manufacturers to be able to offer programmable specificity enzymes, where the sequence recognizedand resulting cutting activity can be precisely directed to any desired point in a DNA, as this will offer opportunity for improvement in many a ...

    STTR Phase II 2013 Department of Health and Human ServicesNational Institutes of Health
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