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Award Data

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The Award database is continually updated throughout the year. As a result, data for FY20 is not expected to be complete until September, 2021.

  1. Conformational Stabilization of the HIV-1 Env Trimer

    SBC: AVATAR MEDICAL, LLC            Topic: NIAID

    DESCRIPTION provided by applicant Avatar is developing HIV vaccine immunogens based on dityrosine DT crosslinking of soluble native Env gp trimers Several of the most potent broadly neutralizing Abs andquot bnAbsandquot preferentially bind native Env trimers and a trimeric immunogen thus would both present a wide range of key neutralizing epitopes and simultaneously focus immune responses away fro ...

    SBIR Phase II 2013 Department of Health and Human ServicesNational Institutes of Health
  2. A Rapid Portable HIV Detection and Monitoring System for Low Resource Settings

    SBC: THERMAL GRADIENT, INC.            Topic: NIAID

    DESCRIPTION provided by applicant Rapid Portable HIV Detection and Monitoring System The long term objectives of this project are Develop a prototype of a rapid portable instrument for detecting and measuring the amount of Human Immunodeficiency Viruses HIVandapos s in samples of patient blood particularly in low resource settings Carry out a pilot study to establish the effectivene ...

    SBIR Phase II 2013 Department of Health and Human ServicesNational Institutes of Health
  3. Approach-specific, multi-GPU, multi-tool, high-realism neurosurgery simulation

    SBC: Kitware, Inc.            Topic: 100

    DESCRIPTION provided by applicant Approach specific Multi GPU Multi tool High realism Neurosurgery Simulation Surgical treatment of neurological diseases is complicated and requires advanced training However compressed internship schedules in hospitals creates a challenge to young surgeons to master techniques needed for such complex procedures Surgical simulators are powerful tools to p ...

    SBIR Phase II 2013 Department of Health and Human ServicesNational Institutes of Health
  4. A Multi-channel Web Platform to Provide Holistic Care to Underserved Consumers

    SBC: Transcendent International, LLC            Topic: NIMHD

    DESCRIPTION provided by applicant Significant obstacles exist in care delivery that prevents meaningful utilization of mental health services by consumers who experience health disparities Specifically individuals facing isolation due to linguistic literacy or cultural bariers often face challenges in procuring mental health care These challenges are in part due to the medical and mental systemsan ...

    SBIR Phase II 2013 Department of Health and Human ServicesNational Institutes of Health
  5. Long-Acting G-CSF Analog for Treating ARS

    SBC: BOLDER BIOTECHNOLOGY INC            Topic: NIAID

    DESCRIPTION provided by applicant Development of radiological nuclear medical countermeasures to treat Acute Radiation Syndrome ARS is a high priority research area for NIAID Bone marrow is one of the most sensitive tissues to radiation damage and impaired hematopoiesis is one of the first clinical signs of excessive radiation exposure often resulting i death Granulocyte colony stimulating ...

    SBIR Phase II 2013 Department of Health and Human ServicesNational Institutes of Health
  6. Development of a Peptidomic Rapid Point-of-Care TB Diagnostic

    SBC: NEW YORK UNIVERSITY            Topic: NIAID

    DESCRIPTION (provided by applicant): Diagnosis of active tuberculosis (TB) in TB-endemic countries, where gt90% of the global TB cases occur, depends upon microscopic examination of sputum smears made directly from the specimen. While this test is highly specific, the test is tedious, time-consuming, requires multiple patient visits, and has limited and variable sensitivity WHO has repeatedly expr ...

    STTR Phase II 2013 Department of Health and Human ServicesNational Institutes of Health
  7. High throughput tau oligomer drug screening assay for Alzheimer's disease

    SBC: Oligomerix, Inc.            Topic: NIA

    DESCRIPTION (provided by applicant): There is a very large and rapidly growing unmet need for disease-modifying drugs for Alzheimer's disease (AD) as its prevalence is increasing worldwide due to demographic shifts in the aging population. AD is the thirdmost costly disease in the US with direct costs over 200 billion annually. The proposed phase IIB program is for the continued development ...

    SBIR Phase II 2013 Department of Health and Human ServicesNational Institutes of Health
  8. Development of hMaxiK bladder wall injection for overactive bladder treatment

    SBC: Ion Channel Innovations, LLC            Topic: NIA

    DESCRIPTION (provided by applicant): This grant application is by Ion Channel Innovations, LLC, (ICI) a company dedicated to the development of naked DNA transfer to treat the unmet needs of people with common smooth muscle diseases that negatively impactthe quality of life of millions. Overactive bladder syndrome (OAB), characterized by symptoms of urinary urgency, frequency, and incontinence, is ...

    SBIR Phase II 2013 Department of Health and Human ServicesNational Institutes of Health
  9. Long-Acting G-CSF Analog for Treating ARS

    SBC: BOLDER BIOTECHNOLOGY INC            Topic: NIAID

    DESCRIPTION (provided by applicant): Development of radiological/nuclear medical countermeasures to treat Acute Radiation Syndrome (ARS) is a high priority research area for NIAID. Bone marrow is one of the most sensitive tissues to radiation damage and impaired hematopoiesis is one of the first clinical signs of excessive radiation exposure, often resulting i death. Granulocyte colony-stimulating ...

    SBIR Phase II 2013 Department of Health and Human ServicesNational Institutes of Health
  10. A Rapid Portable HIV Detection and Monitoring System for Low Resource Settings

    SBC: THERMAL GRADIENT, INC.            Topic: NIAID

    DESCRIPTION (provided by applicant): Rapid, Portable HIV Detection and Monitoring System The long term objectives of this project are: 1. Develop a prototype of a rapid portable instrument for detecting and measuring the amount of Human Immunodeficiency Viruses (HIV's) in samples of patient blood, particularly in low resource settings. 2. Carry out a pilot study to establish the effectiveness ...

    SBIR Phase II 2013 Department of Health and Human ServicesNational Institutes of Health
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