Award Data

Boulder Nonlinear Systems BNS and Prof Edward Boyden s Synthetic Neurobiology Group at the Massachusetts Institute of Technology MIT Media Lab propose to develop a new liquid crystal spatial light modulator SLM capable generating high resolution holograms to overcome the imaging gap that currently divides cellular level optogenetic techniques and whole brain techniques to improve function ...

DESCRIPTION provided by applicant Medical errors are recognized as the cause of numerous deaths and even if some are difficult to avoid many are preventable Computerized physician order entry systems with decision support have been proposed to reduce this risk of medication errors but these systems rely on structured and coded information in the electronic health record EHR Unfortunately ...

The United States has the highest rate of incarceration in the world There are over state and federal prisons housing over million prisoners in the United States The demographics of the prison population are shifting Longer sentences and constrained options for early release compound this trend The older adult segment of prison populations has more than tripled since The health ...

SUMMARY This STTR Phase II proposal addresses the significant need for improved treatment options for patients with liver cancerthe fifth highest incidence of cancer in the worldBecause of the lack of symptomshepatocellular carcinomaHCCis detected at advanced stages inof casesfor which theyear survival rate isand atyears it isThe only curative option for advanced HCC is surgical liver resection an ...

Summary We believe that our project is responsive to the HLS Small Business Topic of Special Interest for NHLBI Fiscal Year Here we will develop commercialization ready advanced functional imager to assess red blood cell RBC transfusion We successfully finished Phase I by developing the device s prototype and testing its functionality in the proof of principle experiments in scatter ...

Among the measures against drunk driving available to policy makers and prevention practitionersResponsible Beverage ServiceRBStraining has shown promiseIn these programsalcohol servers are educated in a number of techniquesincluding correct identification checkingrecognizing signs of intoxication in patronsand managing patrons via drink counting techniques to safely keep them under Driving While ...

Novel Methacrylate Thiol Ene Composites for Dental Restorative Materials As the demand for aesthetically pleasing restorative materials has increased so has the desire and demand for improved performance Despite their increasing prevalence the methacrylate resin phase for the vast majority of these materials has remained largely unaltered since Bowen first proposed the materials nearly year ...

Summary Nearly million wounds are treated in U S emergency departments every year Skin wounds such as severe burns large trauma wounds or non healing chronic wounds that are too extensive or complex to close by natural healing are often reconstructed using autologous skin grafts Although autologous skin grafts are currently the gold standard in complex wound repair there are significant ...

Project Summary Pertussis is rapidly re emerging as a serious public health threat in the United StatesDespite high vaccine coverage nationallyannual reported cases in the U Shave been increasing recentlywith ayear high ofinMoreoverreported cases represent a large underestimate of pertussis infectionsDiagnosis of early pertussiscatarrhal stageprior to paroxysmal coughis particularly challenging be ...

PROJECT SUMMARYRespiratory syncytial virusRSVis the major cause of severe lower respiratory tract infections in children and infantsaffecting an estimatedmillion people and causing up todeaths worldwide per yearWHOIn the USyoung children andadults are hospitalized annually due to RSV infectionHigh risk adultsthe elderly and patients with chronic heart or lung diseaseexperience the highest RSV attr ...