Award Data

Project Summary Environmental risk factors are attributable toof the chronic respiratory disease burden in the U Sand toof the burden from other non communicable diseasese gcancercardiovascular diseaseand diabetesExposure to environmental risk factors occurs through various forms of water and air pollutionwith a smaller attribution to sources like noiseradiationand physical hazardsMuch of this exp ...

Project Summary While studies support the efficacy of comprehensiveschool wide interventions in reducing bullyingthese types of programs can require significant time and financial resources for implementationresulting in barriers to providing school based bullying preventionespecially in low income and rural communitiesAdditionallyalthough training bystanders to act asdefenderson behalf of targets ...

The broader impact/commercial potential of this Small Business Innovation Research (SBIR) Phase I project will result from improving the quality of healthcare in the United States and reducing the associated costs for common elective surgery procedures through evidence-driven patient-physician matching. This technology will improve the quality of care and reduce the variation in costs associated w ...

The broader impact of this Small Business Innovation Research (SBIR) Phase II project safeguards domestic food supply by improving honeybee health. Honeybees pollinate 1/3 of domestic food supply and contribute more than $15 billion to the U.S. economy. Although honeybee populations are at a 20-year high in the U.S., the cost to keep them alive is at its historical peak. This project reduces labor ...

Project Summary Abstract Acute gastroenteritisAGEinfectious diarrhea is a common condition that is costly in the US and highmortality in developing nationsThe cornerstone of AGE management is oral rehydration therapyORTan evidence based technique that has saved overmillion lives in theyears since its introductionThe problem we aim to address is ORT s underuse in developed countries specifically in ...

PROJECT SUMMARY ABSTRACT The performance of many x ray imaging systems is limited by the lack of x ray detectors with simultaneous high quantum efficiency and high spatial resolutionAs examplesdigital mammography scanners typically have a resolution ofm for high quantum efficiencywhich is not sufficient to effectively detect small but critical microcalcificationsX ray micro CT scanners either use ...

The broader impact/commercial potential of this Small Business Innovation Research (SBIR) Phase II project will be to address the lack of advanced maps of shallow water zones, or littoral zones, crucial to global ecology and economy. An estimated 70% of the world's littoral zone is not mapped to modern standards, and traditional methods of mapping these areas are prohibitively expensive and danger ...

Abstract Stress urinary incontinenceSUIcan result from a combinatorial neuromuscular injury to the pudendal nerve and the muscle it innervatesthe external urethral sphincterEUScompounded by the biochemical effects of agingThe mechanisms of SUI development include incomplete pudendal nerve regeneration and EUS sphincter repair from the maternal polytrauma of childbirth as well as biochemical change ...

GravesdiseaseGDis the most common cause of hyperthyroidism and is caused by stimulation of the thyroid stimulating hormone receptorTSHRby thyroid receptor stimulating antibodiesTSAbsTreatment of GD involves antithyroid medication therapyradioactive iodineand surgeryAt the presentfew alternative forms of therapy for GD are available or are in developmentThe ability to block TSHR action may also be ...

In severe persistent hyperinsulinism (HI), repeated hypoglycemic episodes can ultimately lead to permanent seizure disorders, learning disabilities, cerebral palsy, blindness and even death. Clinical studies have demonstrated the effectiveness of both short-term and long-term treatment with glucagon for severe forms of HI and continuous subcutaneous administration of glucagon has been recommended ...