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The Award database is continually updated throughout the year. As a result, data for FY20 is not expected to be complete until September, 2021.

  1. Magnetic Flow Sorter for Pancreatic Islet Isolation

    SBC: TECHSHOT, INC.            Topic: 200

    DESCRIPTION provided by applicant Techshot Inc has successfully completed SBIR Phase I and Phase II research demonstrating that magnetically labeled porcine islets of Langerhans can be isolated from contaminating exocrine tissue by flow sorting using a quadrupole magnetic separator andquot Quadrasepandquot designed for that purpose Magnetically sorted islets are superior in morphology and ...

    SBIR Phase II 2013 Department of Health and Human ServicesNational Institutes of Health
  2. Long-Acting G-CSF Analog for Treating ARS

    SBC: BOLDER BIOTECHNOLOGY INC            Topic: NIAID

    DESCRIPTION provided by applicant Development of radiological nuclear medical countermeasures to treat Acute Radiation Syndrome ARS is a high priority research area for NIAID Bone marrow is one of the most sensitive tissues to radiation damage and impaired hematopoiesis is one of the first clinical signs of excessive radiation exposure often resulting i death Granulocyte colony stimulating ...

    SBIR Phase II 2013 Department of Health and Human ServicesNational Institutes of Health
  3. Frequency Stabilized Laser for use in Microwave Generation

    SBC: Boulder Precision Electro-optics            Topic: SB121001

    This project aims to further develop the technology of frequency stabilized lasers for microwave generation, laser radar and other precision measurement applications. The goal is to decrease the noise floor of the stabilized laser to ~ 6 x 10^-16 at 1 s, and improve operational robustness to allow the device to be transported and operated at the Hz level in stand-alone operation, and mitigate the ...

    SBIR Phase II 2013 Department of DefenseDefense Advanced Research Projects Agency
  4. A Flexible and Extensible Solution to Incorporating New RF Devices and Capabilities into EW/ ISR Networks

    SBC: Adaptive Micro-Ware Inc.            Topic: ST13A004

    There are many different RF devices used in military networks. It is highly desirable to have scalable networks, where new devices can be readily installed without hardware or software changes elsewhere in the network. It is known that achieving this goal

    STTR Phase I 2013 Department of DefenseDefense Advanced Research Projects Agency
  5. Biodegradable, Biocompatible Conductor for Resorbable Medical Implants

    SBC: TDA Research, Inc.            Topic: SB131005

    Advances in biodegradable materials have allowed the development of a variety of resorbable medical devices that do no need to be removed at the end of their service because they degrade within the body into not toxic by-products. However, devices that contain electronic components are still nearly all non-degradable because of the lack of biodegradable conducting and semiconducting materials. T ...

    SBIR Phase I 2013 Department of DefenseDefense Advanced Research Projects Agency
  6. Closed Loop Frequency Control for Tunable High Quality Factor Filters

    SBC: INDIANA MICROELECTRONICS, LLC            Topic: SB12A005

    The proposed project will focus on the development of closed loop frequency control hardware and algorithms for control of high quality factor tunable microwave filters based upon evanescent mode resonators. The developed controller will be integrated with a representative filter. As a system demonstration, the integrated filter/controller module will then be applied to a next generation frequency ...

    STTR Phase II 2013 Department of DefenseDefense Advanced Research Projects Agency
  7. Automated Approaches to Cellular Engineering and Biomanufacturing

    SBC: Covitect Inc.            Topic: ST12B003

    Genome-scale predictable cellular design and engineering of biomanufacturing systems is the overarching a goal of DARPA's Living Foundry thrust and, if realized, will enable rapid engineering of living biosystems for a broad range of applications in biotechnology and pharmacology. However, constructing living cells with designed genome is not fully automated and is severely limited by inhere ...

    STTR Phase I 2013 Department of DefenseDefense Advanced Research Projects Agency
  8. Inhibitors of Mycobacterial Protein Tyrosine Phosphatase B (mPTPB) for therapy of

    SBC: AARDEN PHARMACEUTICALS, INC.            Topic: NIAID

    DESCRIPTION (provided by applicant): Inhibitors of Mycobacterial Protein Tyrosine Phosphatase B (mPTPB) for therapy of tuberculosis Aarden Pharmaceuticals Project Summary/Abstract The need exists for a new, breakthrough therapeutic for tuberculosis (TB). Current treatment regimens with toxic chemotherapeutic drugs are too long, causing poor compliance which results in reduced efficacy and the emer ...

    STTR Phase I 2013 Department of Health and Human ServicesNational Institutes of Health
  9. Biomarker discovery for immunodiagnosis of invasive candidiasis

    SBC: DxDiscovery Incorporated            Topic: NIAID

    DESCRIPTION (provided by applicant): Invasive candidiasis (IC) is one of the most serious threats to patients in a critical setting. With as many as 60,000 cases per year in the U.S., the total cost associated with IC in the U.S. may be as high as 2-4 billion/year. One of the most critical factors influencing patient outcome is early diagnosis. The goal of this project is a rapi and inexpensive i ...

    STTR Phase I 2013 Department of Health and Human ServicesNational Institutes of Health
  10. Elucidation of Antisickling Molecules in a Botanical with Antisickling Activity

    SBC: INVENUX, LLC            Topic: NCCAM

    DESCRIPTION: New therapeutic agents are urgently needed for the treatment of sickle cell disease (SCD), the world's most common genetic disease. Our long-term goal is to develop a drug for use in children that prevents the inexorable progression of SCD. SCD affects approximately 100,000 people in the United States and millions worldwide. It kills more children in Africa than HIV, but while HI ...

    STTR Phase I 2013 Department of Health and Human ServicesNational Institutes of Health
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