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The Award database is continually updated throughout the year. As a result, data for FY20 is not expected to be complete until September, 2021.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

  1. "A Tool to Improve Evaluation of Patient Navigation Services in Under-served Populations"

    SBC: NATIVE AMERICAN CANCER INITIATIVES, INC.            Topic: NIMHD

    Native American Cancer Initiatives Inc NACI is a woman owned minority American Indian business with fewer than three full time equivalent employees This for profit company founded in has the mission to provide technical assistance and products to communities patients researchers academicians universities research institutions and professionals on Native Americans cultural iss ...

    SBIR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  2. A next generation spatial light modulator for mapping of neural networks

    SBC: BOULDER NONLINEAR SYSTEMS, INC.            Topic: NIBIB

    Boulder Nonlinear Systems BNS and Prof Edward Boyden s Synthetic Neurobiology Group at the Massachusetts Institute of Technology MIT Media Lab propose to develop a new liquid crystal spatial light modulator SLM capable generating high resolution holograms to overcome the imaging gap that currently divides cellular level optogenetic techniques and whole brain techniques to improve function ...

    SBIR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health
  3. Large-aperture electrically tunable lenses with 1ms hysteresis-free response for remote focusing

    SBC: BOULDER NONLINEAR SYSTEMS, INC.            Topic: NIBIB

    Project summary The fast millisecond timescale of neuronal activity has posed a difficulty for D volumetric imaging whose speed is limited in part by the axial scan methods currently available The use of electrically tunable lenses ETLs for remote focusing confers speed and vibration reduction advantages over the more traditional sample stage or microscope objective motion but current state ...

    SBIR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  4. Point of care immunoassay for rapid diagnosis of tinea capitis

    SBC: DxDiscovery Incorporated            Topic: NIBIB

    Tinea capitis scalp ringworm is a fungal dermatophyte infection of scalp hair follicles that afflicts of the U S pediatric population Tinea capitis is a major health care disparity because it occurs predominantly among individuals with a disadvantaged socioeconomic background and sub Saharan African descent Diagnosis of tinea capitis is currently dependent on culture and microscopy Both ...

    SBIR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  5. Enhancing Care of the Aged and Dying in Prisons

    SBC: KLEIN BUENDEL, INC            Topic: NIA

    The United States has the highest rate of incarceration in the world There are over state and federal prisons housing over million prisoners in the United States The demographics of the prison population are shifting Longer sentences and constrained options for early release compound this trend The older adult segment of prison populations has more than tripled since The health ...

    STTR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health
  6. Developing novel RPPA for the detection of metastatic prostate cancer

    SBC: Tymora Analytical Operations, LLC            Topic: 102

    PROJECT SUMMARY Reverse phase protein arrayRPPAhas emerged as a promising antibody based highly quantitative proteomic technology suitable for profiling proteins in hundreds to thousands of patient samplesThe throughputsensitivityand cost effectiveness of RPPAtogether with its ability to deal with minuscule sample amountshave propelled applications of the technology in basicpreclinical and clinica ...

    STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  7. Plasma Generation of Aqueous Chemotherapeutic Solutions

    SBC: SYMBIOS TECHNOLOGIES INC.            Topic: 102

    Despite significant advances in chemotherapeutic approaches due to new drugs and combinatorial therapies over the past decades cancer is still the second leading cause of death in the United States Further pancreatic cancer is one of the most aggressive and deadly cancer types with only a chance of patient survival five years past diagnosis In this Phase I SBIR proposal the Tubular Plasma ...

    SBIR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  8. High speed Intraoperative Assessment of Breast Tumor Margin using MarginPAT

    SBC: Vibronix, Inc.            Topic: O

    After a breast conserving therapy histology is often performed to check whether the excised tumor specimen is surrounded by a sufficient amount of normal tissue If a positive margin is identified then a second operation will be performed Currently the re operation rate is which raises a need for intraoperative detection of residual cancers The current intraoperative tools for margin ...

    STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  9. WayToServe Espanol: A Culturally-Appropriate Online Responsible Beverage Service Training for Spanish-Speaking Servers

    SBC: KLEIN BUENDEL, INC            Topic: 102

    Among the measures against drunk driving available to policy makers and prevention practitionersResponsible Beverage ServiceRBStraining has shown promiseIn these programsalcohol servers are educated in a number of techniquesincluding correct identification checkingrecognizing signs of intoxication in patronsand managing patrons via drink counting techniques to safely keep them under Driving While ...

    SBIR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health
  10. Personalized dosing of dichloroacetate for the treatment of rare and common diseases

    SBC: Medosome Biotec, LLC            Topic: NICHD

    ABSTRACT SUMMARY Pyruvate dehydrogenase complex PDC deficiency PDCD is a rare disease of mitochondrial energy failure in which the life of expectancy of affected children is severely truncated Treatment of PDCD remains a serious unmet challenge There has never been a controlled trial of any intervention for PDCD thus there is no proven therapy for affected patients Dichloroacetate DCA ...

    STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
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