Award Data

DESCRIPTION provided by applicant Retinal prosthetic devices currently under development are designed to bypass the non functioning portion of the visual pathway photoreceptor layer in individuals suffering from diseases including retinitis pigmentosa RP and age related macular degeneration AMD Current devices enable patients to only see object positions and read large letters and furth ...

DESCRIPTION provided by applicant Hypersecretion of mucus into the respiratory airways is a major contributing factor in several lung diseases including chronic pulmonary disease COPD asthma cystic fibrosis allergic rhinitis and bronchiectasis Despite the obvious medical importance there presently are no effective therapies to control excess mucus secretion in these diseases and very ...

DESCRIPTION provided by applicant Thyroid cancer is the most common type of endocrine malignancy New thyroid cancers patients are identified daily and most patients live for decades following diagnosis Thyroglobulin TG levels in the sera or in fine needle biopsies of thyroid cancer patients are routinely quantified using various agency approved e g FDA immunoassays for diagnostic and p ...

DESCRIPTION provided by applicant This Phase IIB SBIR application is responsive to NHLBI RFA HL andquot NHLBI SBIR Phase IIB Bridge Awards to Accelerate the Commercialization of Technologies for Heart Lung Blood and Sleep Disorders and Diseases R andquot This RFA solicits work on andquot basic applied and clinical research on all product and service development related to the ...

DESCRIPTION provided by applicant Schizophrenia is one of the most debilitating and costly mental illnesses in the United States with peak incidence in individuals aged and causing annual direct and indirect costs of over $ billion Wu et al Several studies suggest that early identification and treatment can delay onset and decrease the severity of schizophrenia leading to a significant reduction i ...

DESCRIPTION provided by applicant Development of radiological nuclear medical countermeasures to treat Acute Radiation Syndrome ARS is a high priority research area for NIAID Bone marrow is one of the most sensitive tissues to radiation damage and impaired hematopoiesis is one of the first clinical signs of excessive radiation exposure often resulting i death Granulocyte colony stimulating ...

DESCRIPTION provided by applicant The purpose of this SBIR project is to develop a new tool to improve the ability of blind and visually impaired people to quickly get to the right web pages to avoid ending up on the wrong web pages and to reach the desired part of each web page efficiently The motivation for this effort is that getting a andapos big pictureandapos understanding of a web page is o ...

This Small Business Innovation Research (SBIR) Phase II project aims to develop a micro-electro-mechanical system (MEMS)-based moisture (dew point) measurement instrument. Trace moisture measurements are needed in a variety of industrial sectors including natural gas production and distribution, semiconductor manufacturing, pure gas supply, aerospace, and petrochemical processing. Commercially-ava ...

This Small Business Innovation Research Phase I project will investigate the commercial potential of flash-sintering to enhance the manufacturability and performance of Solid Oxide Fuel Cells (SOFCs). The co-sintering of heterogeneous multilayer ceramics remains a technical barrier to the commercialization of SOFCs for two reasons: 1) the materials for the multilayer structure require different pr ...

This Small Business Technology Transfer (STTR) Phase I project proposes to improve intrinsic crop yield through metabolic engineering of photosynthetic pathways. Genes encoding five rate-limiting enzymes for photosynthesis and starch synthesis will be co-expressed constitutively or in a cell-specific manner in a model C4 plant species. Multiple metabolic pathways will be altered to simultaneously ...