Award Data

DESCRIPTION provided by applicant Avatar is developing HIV vaccine immunogens based on dityrosine DT crosslinking of soluble native Env gp trimers Several of the most potent broadly neutralizing Abs andquot bnAbsandquot preferentially bind native Env trimers and a trimeric immunogen thus would both present a wide range of key neutralizing epitopes and simultaneously focus immune responses away fro ...

DESCRIPTION provided by applicant Rapid Portable HIV Detection and Monitoring System The long term objectives of this project are Develop a prototype of a rapid portable instrument for detecting and measuring the amount of Human Immunodeficiency Viruses HIVandapos s in samples of patient blood particularly in low resource settings Carry out a pilot study to establish the effectivene ...

DESCRIPTION provided by applicant Approach specific Multi GPU Multi tool High realism Neurosurgery Simulation Surgical treatment of neurological diseases is complicated and requires advanced training However compressed internship schedules in hospitals creates a challenge to young surgeons to master techniques needed for such complex procedures Surgical simulators are powerful tools to p ...

DESCRIPTION provided by applicant Significant obstacles exist in care delivery that prevents meaningful utilization of mental health services by consumers who experience health disparities Specifically individuals facing isolation due to linguistic literacy or cultural bariers often face challenges in procuring mental health care These challenges are in part due to the medical and mental systemsan ...

DESCRIPTION provided by applicant Development of radiological nuclear medical countermeasures to treat Acute Radiation Syndrome ARS is a high priority research area for NIAID Bone marrow is one of the most sensitive tissues to radiation damage and impaired hematopoiesis is one of the first clinical signs of excessive radiation exposure often resulting i death Granulocyte colony stimulating ...

DESCRIPTION provided by applicant Tuberculosis TB disease which results from infection with Mycobacterium tuberculosis Mtb is a leading cause of infectious morbidity and mortality in children andlt years old worldwide In TB endemic regions in which the vast majority of the worldandapos s annual million adult cases of TB disease reside children andlt years old account for ...

The proposed goal of Nevada Nanotech Systems Inc for the Phase I program is to select a practical technological solution and develop a Con-Ops for the problem of detecting U.S. currency via unique vapor signature(s) in confined spaces for three related, though unique, application scenarios (bags, vehicles, and shipping containers). Nevada Nano will document a matrix of technical and operational re ...

To meet the critical security needs of the Department of Homeland Security and others, we propose two methods for providing a secure root of trust for mobile devices. One method is designed to integrate as easily into existing systems, while the other requires deeper integration but provides correspondingly stronger security. The keys to our work are practicality and integration: practicality to e ...

For Phase II work, we propose to complete the development of the DICOS compliant ATR algorithm whose feasibility has been demonstrated by results of Phase I work. Important project milestones for the first base year of Phase II are as follows: (1) implementation of the DICOS standard including network protocol, (2) improvement of the proposed ATR algorithm in terms of explosive detection performan ...

The personal protective equipment (PPE) worn by firefighters (turnout Gear, SCBA, helmet, etc.) protects the wearer against burns and hazardous environments. Unfortunately, they work so well that they decrease the firefighter's situational awareness, in particular their ability to notice rapidly increasing temperatures. Although current thermal sensor technologies (generally built in to the Pers ...