Award Data

DESCRIPTION provided by applicant Multi drug resistance in Enterobacteriaceae is regarded as a healthcare crisis While carbapenems are among the most prescribed antibiotics for infections caused by these organisms carbapenem resistance conferred by zinc based metallo carbapenemases Amber Class B is a growing global health concern that threatens to erode the efficacy of these antibiotics both in th ...

DESCRIPTION provided by applicant Multi drug resistance in Enterobacteriaceae is regarded as a healthcare crisis This crisis has been further amplified by the recent emergence of the NDM andquot super bug geneandquot a zinc based metallo lactamase Amber Class B in Enterobacteriaceae Members of this family of resistance enzymes are found on promiscuous plasmids with other MDR resistance mechanisms ...

DESCRIPTION provided by applicant Development of a urine test for the early detection of liver cancer The need to develop an effective method of detecting hepatocellular carcinoma HCC is urgent HCC is the third leading cause of cancer deaths and has a year survival rate of less than If HCC is identified early the survival rate can be as high as The survival rate drops significantly however to as l ...

DESCRIPTION provided by applicant Development of radiological nuclear medical countermeasures to treat Acute Radiation Syndrome ARS is a high priority research area for NIAID Bone marrow is one of the most sensitive tissues to radiation damage and impaired hematopoiesis is one of the first clinical signs of excessive radiation exposure often resulting i death Granulocyte colony stimulating ...

DESCRIPTION provided by applicant In this Phase II NIH SBIR Actuated Medical Inc will complete the development of the Pedi GJ ClearTM device for clearing occlusions and restoring patency in situ to pediatric gastrojejunal feeding tubes GJ tubes eliminating the need to surgically replace clogged tubes Public Health Problem Enteral nutrition is provided for patients that have a functioning lower gas ...

This project targets the development of a commercially viable silicon-nitride (SiN) Atomic Layer Deposition (ALD) process for gallium nitride (GaN) Monolithic Microwave Integrated Circuits (MMICs) applications. In particular, this project will provide a higher quality substitution for commonly used PEVCD SiN passivation layers. These better passivation layers will enable the development and manufa ...

Fiber reinforced composites are attractive for several light-weight defense and aerospace applications. However, their inherent anisotropy and complex failure mechanisms limit their use in high-performance structures or components. In order to accurately predict the damage behavior and durability of composite parts exposed to extreme conditions, there is a need to develop new analysis tools that c ...

Present sonobuoys allow for the selection of functions such as RF Channel, Depth, etc. by use of a single selector button and LED display along with a second button used for verification located on the side of the sonobuoy. Selection or verification requires access to the buttons and cannot be accomplished once the sonobuoy is loaded into the launcher. The capability to select and verify functions ...

Marine-grade aluminum alloys (5XXX-series) are increasingly being used in naval combatants because they have high strength and high corrosion resistance. In order to decrease weight, these corrosion resistant marine-grade aluminum alloys are not painted with the conventional primer and low solar absorbance topcoats. Although 5XXX series wrought aluminum alloys generally exhibit excellent corrosion ...

In this Phase II SBIR project, Daniel H. Wagner Associates (DHWA), with NASAs Jet Propulsion Laboratory (JPL), MARK Resources, Inc. (MRI), and Spatial Integrated Systems (SIS) as our subcontractors, will develop a prototype lightweight, low-cost Wave Detection, Prediction, and Reaction System (WDPRS), and then test and evaluate its performance at-sea. The proposed WDPRS is designed to reduce the h ...