Award Data

In this Phase II STTR proposal we will demonstrate the scalability and ruggedness of the production system necessary for the commercialization of the goose egg-derived immunoglobulin product that is a countermeasure to the lethal (40 %) Hantavirus Pulmonary Syndrome caused by Andes Virus (ANDV). A major objective will be creating a Quality System (QS) around the global process that aligns it with ...

Decontamination of chemical and biological threats demands a very reactive solution. It is ideal to generate the decontaminants on-site: the activated decontaminant is highly reactive and quickly destroys chemical and biological warfare agents; prior to activation the ingredients can be safely stored for years, shipped, and handled. TDA's electrochemical decontamination (eClO2) technology u ...

Approximately 5-6% of military injuries involve some form of major peripheral nerve injury with little chance of spontaneous healing. Currently these injuries lead to major impairment of voluntary muscle function in the limbs and extremities, making tasks of walking, reaching, grasping, etc. very difficult or impossible for many patients. It is not enough to focus therapeutic treatment on the se ...

This Small Business Technology Transfer (STTR) Phase I effort will demonstrate the feasibility of an innovative tungsten carbide (WC) metal matrix composite for use as a non-carcinogenic penetrator for armor piercing (AP) munitions for small arms. The objectives of this effort are to: 1) Mechanically compact the WC and binder powders, 2) Sinter the compacted powders into a fully dense composite, 3 ...

The neurocognitive health of U.S. service members plays a vital role in the defense of the United States. It is critical to a service member"s effectiveness, to force readiness, and it is a key component of a service member"s successful reintegration into family life and society following deployment. Increased rates of mild traumatic brain injury (mTBI) and psychological health problems experien ...

In this Phase I STTR proposal we will determine the ruggedness of the genetic immunization technique in the production of duck egg derived immunoglobulin; specifically the natural F(ab")2 analog, IgY^Fc. We have already demonstrated that potently neutralizing duck egg antibodies generated with an early candidate Andes virus DNA vaccine, delivered via intramuscular electroporation, can protect afte ...

The objective of this Phase 1 effort is to develop an asymmetric supercapacitor (ASC) that provides>10 Wh/kg energy density and a high power density, and maintains this performance down to -55 degrees C. Yardney Technical Products (YTP), a recognized specialty high energy battery manufacturer in Pawcatuck, CT in collaboration with the Jet Propulsion Laboratory (JPL) proposes to design, develop and ...

Today's military equipment is required to operate in extreme conditions: frigid arctic locations, dry/hot deserts, and humid tropical jungles, which leads to design operating temperature ranges of approximately -50degreesC to 70degreesC for current power systems. No commercial electric power storage device can perform at high rates at the lower limits of this temperature range, and technolo ...

On-site activated decontaminants are ideal because the activated solution is highly reactive and can quickly destroy chemical and biological warfare agents, but prior to activation the decontaminant ingredients can be safely stored for years, shipped, handled and have a long shelf life. TDA"s electrochemical decontamination (EC-Decon) technology utilizes electrical activation of an inert salt sol ...

Thermopile infrared linear arrays manufactured using CMOS integrated circuit processes and micro-machining will provide high performance sensing with low manufacturing cost. Black Forest Engineering (BFE) teamed with Case Western Reserve University will d