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The Award database is continually updated throughout the year. As a result, data for FY20 is not expected to be complete until September, 2021.

  1. Proprietary biologic treatment to heal skin wounds

    SBC: Allander Biotechnologies            Topic: NIDCR

    SUMMARY Chronic skin wounds associated with various diseasese gdiabetesand aberrant healing from acute woundinge ghypertrophic scarringare a major health care burdenThis health burden increases in aging populationsThe cost to treat these conditions exceeds $billion annuallyCurrentlyREGRANEXa cream containing a biologic based on human PDGFPlatelet Derived Growth Factoris the only FDAFood and Drug A ...

    SBIR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health
  2. Development of a Clinical Screening Platform for Type 1 Diabetes

    SBC: Op-T-Mune, Inc            Topic: NIDDK

    AbstractA major shortfall in clinical care for diabetes is a rapid and accurate screen for progression to diseaseCurrent criteria involve HLA haplotypeand the presence of auto antibodiesAAGenome wide associated studiesGWASrevealed only immune associated genes including HLA as T D predictorsThe ability to differentiate from other diseases was very limitedPre typediabetesp T Dis now being identified ...

    STTR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health
  3. PINPOINT: Gaming technology to engage adolescent sickle cell patients in precision pain Phase I

    SBC: KLEIN BUENDEL, INC            Topic: 102

    Sickle cell diseaseSCDis the most common inherited blood disorder in the U Sand disproportionately affects African Americans and HispanicsApproximatelyU Schildren are born with SCD annuallySCD results from abnormal hemoglobin and causes red blood cellsRBCsto become misshapedsickle shapedSickled cells can block the flow of blood in small arteries causing tissue and organ damage and other lifethreat ...

    SBIR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health
  4. Smartphone Help for DWI Offenders and Their Families: A B-SMART App

    SBC: KLEIN BUENDEL, INC            Topic: 450

    Driving while intoxicatedDWIremains a substantial and preventable source of morbidity and mortality in the United StatesA variety of sanctions and interventions have been attempted to reduce DWI in the U Sincluding enhanced DWI enforcement effortsstricter drunk driving lawsresponsible alcohol beverage service trainingand alcohol treatmentThe Ignition Interlock DeviceIIDwhich requires a driver to b ...

    SBIR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health
  5. Caminamos: A location-based Smartphone App for Latinas to Connect with Nearby Walking Partners

    SBC: KLEIN BUENDEL, INC            Topic: 102

    Health disparities are high among LatinasThey are more likely to be overweightdiagnosed with diabetesand physically inactive compared to their non Hispanic White counterpartsThusinterventions that target improving health access and ameliorating chronic diseases among Latinas are of high public health importanceAvailable data suggest that community focused interventions produce improvements in phys ...

    SBIR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health
  6. A Tool to Improve Evaluation of Patient Navigation Services in Underserved Populations

    SBC: NATIVE AMERICAN CANCER INITIATIVES, INC.            Topic: 102

    Native American Cancer InitiativesIncNACIis a woman ownedminorityAmerican Indianbusiness with fewer than three full time equivalent employeesThis for profit companyfounded inhas the mission to provide technical assistance and products on Native Americanscultural issuesevaluationprogram development and assessment and cancer care across the continuumoutreach through end of life careto communitiespat ...

    SBIR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health
  7. Novel Polymer Matrix for Dental Applications

    SBC: TDA Research, Inc.            Topic: NIDCR

    Project SummaryAbstract Dental caries are the most common childhood disease in the United StatesDental sealants are materials that are applied to the pits and fissures of healthy teeth to prevent dental caries or other forms of decayThis method prevents bacteria ingress and acid dissolution and targets the portions of the tooth surface whereof the decay developsSealants are safe and effective in p ...

    SBIR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health
  8. Cuff Electrodes with Soft Wire Electrical Leads

    SBC: TDA Research, Inc.            Topic: 102

    Project Summary AbstractDevelopment of a Nerve Cuff Electrode from Soft and Elastomeric Conducting Wires STTR Phase I ApplicationPIBrady ClapsaddleTDA ResearchIncBio electronic interfaces are used in a wide array of applications for recording and providing electrical impulses to treat diseaseOne common interface device for the PNS is the cuff electrodeCurrent cuff electrodes have many failure mode ...

    STTR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  9. Low-cost Personal Sampling Pump

    SBC: Access Sensor Technologies LLC            Topic: NIOSH

    ! Project Summary Exposure to particulate matterPMair pollution is the fifth leading cause of premature disease and death on the planet and the number one environmental risk factor for the global burden of diseaseposing a greater danger than all other environmental risk factors combinedaccording to the World Health OrganizationDespite the growing needand demandthe state of the art for assessing pe ...

    SBIR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health
  10. GAA-ITEM: Personalizing the Prediction of Anti-therapeutic Antibody Response in Pompe Disease Patients

    SBC: EPIVAX, INC.            Topic: 999

    Abstract SignificanceInfantile Pompe DiseaseIPDis an autosomal recessive glycogen storage disorder caused by a deficiency of acid alpha glucosidaseGAAleading to accumulation of glycogen in lysosomesprimarily in skeletalcardiac and smooth musclesUntreated IPD infants die within the firstyears of lifeEnzyme replacement therapyERTwith recombinant human GAArhGAAimproves survival and quality of lifebut ...

    SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
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