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Award Data

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The Award database is continually updated throughout the year. As a result, data for FY20 is not expected to be complete until September, 2021.

  1. SBIR Phase II: Novel platform for the preparation of samples for cryo-TEM imaging: capturing biomacromolecules repeatably in vitreous ice without artifacts

    SBC: NanoSoft, LLC            Topic: MI

    The broader impact of this Small Business Innovation Research (SBIR) Phase II project is a new way to prepare samples for life sciences research by addressing the major bottleneck in the associated workflow. The proposed work advances a new method to prepare biological samples for analysis to develop crisp, high-resolution 3D models of molecules. This will result faster acquisition of higher quali ...

    SBIR Phase II 2020 National Science Foundation
  2. SBIR Phase I: Machine Learning Driven Synthetic Sensor for Plant Water Stress

    SBC: Aquasys LLC            Topic: CT

    The broader impact/commercial potential of this Small Business Innovation Research (SBIR) project is to increase yields and save irrigation water and costs for farmers of perennial crops and high intensity annual crops. In order to maximize yields while simultaneously minimizing irrigation water usage, farmers need to understand, predict, and manage plant water stress, which is the yield reducing ...

    SBIR Phase I 2019 National Science Foundation
  3. SBIR Phase I: General-Purpose Software for Collaborative End-User Database Management

    SBC: Ultorg LLC            Topic: IT

    The broader impact/commercial potential of this Small Business Innovation Research (SBIR) Phase I project will be to make organizations more productive by helping them organize operational data in a structured yet accessible way. Today, organizations tend to accumulate such data in spreadsheets, scattered across users and folders, with new copies and revisions being made every time data must be pr ...

    SBIR Phase I 2019 National Science Foundation
  4. SBIR Phase I: Encrypted Databases: From Theory to Systems

    SBC: SIFR SYSTEMS, INC.            Topic: IT

    The broader impact/commercial potential of this Small Business Innovation Research (SBIR) Phase I project consists of (1) preventing server-level data breaches; and (2) increasing adoption of cloud computing; especially in sectors that inherently deal with sensitive data and are subject to regulation. This includes the healthcare and finance industries as well as government agencies. Data breaches ...

    SBIR Phase I 2019 National Science Foundation
  5. Noninvasive Functional Cortical Mapping with Innovative tEEG

    SBC: CREmedical Corp            Topic: 106

    PROJECT SUMMARY Resective neurosurgery is essential for treating a range of neurologic conditions such as epilepsy and brain tumorsFor some patientswhose lesion is close to cortical language areaspostoperative expressive or receptive language deficit is a major and feared postoperative complicationMuch effort is devoted to identifying the cortical language regionsand relating such localization to ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  6. A multivalent, easy-to-use product to mitigate and treat radiation exposure

    SBC: FIBROPLATE, INC            Topic: NIAID

    ABSTRACTThe threat of radiological and nuclear accidents or attacks demands for effective radiation medical countermeasuresMCMable to mitigate and treat the effects of exposure to ionizing radiationsHematopoietic acute radiation syndromeHRASand cutaneous radiation syndromeCRSpose severelife threatening risks to exposed individualsCurrently no effective radio mitigatorto be administered after radia ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  7. Immunoassay for early diagnosis of mucormycosis

    SBC: DxDiscovery Incorporated            Topic: NIAID

    Mucormycosis is one of the deadliest of the invasive fungal infectionsMucormycosis occurs most often in patients with hematological malignancies undergoing chemotherapypatients who have received hematopoietic stem cell transplants or patients with diabetes mellitusImproved diagnosis is the most frequently noted unmet need for management of the mucormycosis patientDelays in treatment increase the m ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  8. Developing, Testing and Validating a Wearable Alcohol Biosensor

    SBC: Clinitech, LLC            Topic: 450

    PROJECT SUMMARYThis application for a Phase II SBIR award extends the successful completion of Phase I and represents acollaboration between ClinitechLLC and McLean Hospital Harvard Medical School to continue thedevelopment of a wearable biosensor for detecting alcohol in the interstitial fluid of humansExcessive use ofalcohol accounts for much of the public health burden related to alcohol use di ...

    SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  9. Development of a lead cyclic-PDZ-Enhancer drug for Anxiety and Depression

    SBC: Aingeal, LLC            Topic: 101

    Major depressive disorder is a debilitating mood disorder that affectsof US adults in their lifetimecosting the U Seconomy more than $billion a yearDrugs that increase monoaminergic signaling are the mainstay of depression therapybut have a delayed onset of action and are only effective in aboutof affected patientsAberrant brain derived neurotrophic factorBDNFsignaling has been proposed to underli ...

    STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  10. Lateral flow immunoassay for rapid diagnosis of tinea capitis and onychomycosis

    SBC: DxDiscovery Incorporated            Topic: NIBIB

    Tinea capitisringworm of the scalpand onychomycosisfungal nail infectionare infections that are most often caused by dermatophytes of the fungal genera Trichophyton and MicrosporumThese two infections affect approximatelymillion people in the U Seach yearDermatophyte infections of the hair and nails are treated with oral antifungals for up toweeksDue to potential adverse effectsboth the American A ...

    SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
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