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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. VLP-Based Antibody-Inducing Vaccines for HIV-1

    SBC: ALTRAVAX, INC            Topic: NIAID

    DESCRIPTION (provided by applicant): The HIV-1 epidemic has resulted in ~2.7 million new infections in 2007 for a total of ~33 million people living with HIV/AIDS. Clinical trials have shown that HIV-1 infection cannot be prevented by immunization with monomeric recombinant forms of viral envelope (Env) proteins. However, it is clear that the HIV-1 Env contains epitopes that can induce neutralizin ...

    SBIR Phase I 2010 Department of Health and Human ServicesNational Institutes of Health
  2. Improved Vaccines for Influenza B Virus

    SBC: ALTRAVAX, INC            Topic: NIAID

    DESCRIPTION (provided by applicant): Influenza is a major cause of morbidity and mortality around the world. In the United States, seasonal epidemics of flu occur from late fall to early spring affecting all age groups but with especially high rates of infection in children. Serious illness and death are consequences of influenza infection among the elderly, young children, and individuals with o ...

    SBIR Phase I 2010 Department of Health and Human ServicesNational Institutes of Health
  3. Designing Improved HIV-1 Envelope Proteins as Vaccine Candidates

    SBC: ALTRAVAX, INC            Topic: NIAID

    DESCRIPTION (provided by applicant): The HIV-1 epidemic has resulted in ~2.7 million new infections in 2007 for a total of ~33 million people living with HIV/AIDS. Clinical trials have shown that HIV-1 infection cannot be prevented by immunization with monomeric recombinant forms of viral envelope (Env) proteins. However, it is clear that the HIV-1 Env contains epitopes that can induce neutralizin ...

    SBIR Phase I 2010 Department of Health and Human ServicesNational Institutes of Health
  4. Optical Fluorescence and X-Ray Computed Tomography Scanner for Small Animal In-Vi

    SBC: BIOSCAN, INC.            Topic: NCRR

    DESCRIPTION (provided by applicant): The overall goal of this application is to develop a quantitative in-vivo small animal imaging system for fluorescent reporter probes that fuses fluorescence light emitting computed tomography (FLECT) with X- ray computed tomography (CT). The proposed dual-modality imaging system will not only provide a research tool for better understanding of biological funct ...

    SBIR Phase I 2010 Department of Health and Human ServicesNational Institutes of Health
  5. Prevention of College Student Mental Health Problems: A Web-Based ACT Program

    SBC: CONTEXTUAL CHANGE, LLC            Topic: NIMH

    DESCRIPTION (provided by applicant): There is a strong need for the development and dissemination of effective prevention programs for mental health problems with college students, who are at risk for depression, anxiety, eating disorders, substance use, and many other difficulties (American College Health Association, 2007). Despite the fact that University settings are well suited to deliver suc ...

    SBIR Phase I 2010 Department of Health and Human ServicesNational Institutes of Health
  6. Scalable Production of New Generation Adeno-Associated Virus Gene Therapy Vectors

    SBC: REGENX BIOSCIENCES, LLC            Topic: NIDDK

    DESCRIPTION (provided by applicant): The overall goal of this application is to develop a scalable production system for the manufacture of an adeno- associated virus (AAV) serotype 8-based gene therapy vector bearing a human low density lipoprotein receptor (hLDLR) transgene for the treatment of familial hypercholesterolemia (FH). Recombinant AAV8 vector is one of a group of new generation vector ...

    SBIR Phase I 2010 Department of Health and Human ServicesNational Institutes of Health
  7. Immunotherapeutic Biomaterials for Treatment of Glioma

    SBC: IN CYTU, INC.            Topic: NINDS

    DESCRIPTION (provided by applicant): A Phase I SBIR program of preclinical development is proposed focusing on the development of an active specific immunotherapeutic called Cellarium for treatment of glial cell-based cancers. Successful completion of this project will establish the minimum level of therapeutic feasibility and lead to further development of the vaccine in preparation for f ...

    SBIR Phase I 2010 Department of Health and Human ServicesNational Institutes of Health
  8. N/A

    SBC: ABACUS HEALTH SOLUTIONS, LLC            Topic: N/A

    N/A

    SBIR Phase I 2000 Department of Health and Human ServicesNational Institutes of Health
  9. N/A

    SBC: ABACUS HEALTH SOLUTIONS, LLC            Topic: N/A

    N/A

    SBIR Phase I 2000 Department of Health and Human ServicesNational Institutes of Health
  10. N/A

    SBC: ABACUS HEALTH SOLUTIONS, LLC            Topic: N/A

    N/A

    STTR Phase I 2000 Department of Health and Human ServicesNational Institutes of Health
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