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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

Displaying 1 - 10 of 3023 results
  1. Targeting Myosin to Treat Polycystic Kidney Disease

    SBC: PLUREXA LLC            Topic: 400

    PROJECT SUMMARY The goal of this proposal is to advance a new therapeutic approach targeting myosin for polycystic kidney disease (PKD). PKD is a major life-threatening Mendelian disorder that affects 12,000,000 individuals, representing a market opportunity of ~$1 billion. In PKD, tiny tubules in the kidneys, liver, and other organs gradually expand into fluid-filled cysts, leading to organ failu ...

    STTR Phase I 2023 Department of Health and Human ServicesNational Institutes of Health
  2. Precision MRI with a Novel Protein Contrast Agent for Early Detection and Staging of Lung Fibrosis

    SBC: INLIGHTA BIOSCIENCES L.L.C.            Topic: NHLBI

    Summary Lung diseases, such as interstitial lung diseases including idiopathic pulmonary fibrosis (IPF), chronic obstructive pulmonary disease (COPD), and acute viral infection are major leading causes of death worldwide. The recent increase due to air pollution, tobacco smoking is and use of E-cigarettes has grown rapidly in the US contributing to a sharp increase in chronic lung diseases. IPF is ...

    STTR Phase I 2023 Department of Health and Human ServicesNational Institutes of Health
  3. Dialysate regeneration system based on photo-electrochemical urea oxidation and reactive adsorption to enable portable hemodialysis

    SBC: KULEANA TECHNOLOGY, INC.            Topic: 400

    PROJECT SUMMARY/ ABSTRACT Currently in the US there are over 400,000 kidney patients on dialysis. The primary therapy mode is hemodialysis and is performed in a hospital or private clinic. Current dialysis therapy requires a large device that must be continuously connected to a reverse osmosis (RO) system. A single treatment will require over 150L of AAMI dialysate making portable device unattaina ...

    STTR Phase I 2023 Department of Health and Human ServicesNational Institutes of Health
  4. Ultra-low Fouling and Anti-infective and Anti-thrombotic Nitric Oxide Releasing Intravascular Catheters

    SBC: NYTRICX INC            Topic: NHLBI

    Abstract Nytricx is developing a new class of Nitric Oxide (NO)-releasing intravascular medical catheters to combat infection and thrombosis associated with indwelling vascular catheters. NO gas is a natural anti-infective and anti-thrombotic human product principally released from blood vessels and immune cells. Nytricx NO-releasing technology to the catheter surfaces via a polymer matrix, mimics ...

    STTR Phase II 2023 Department of Health and Human ServicesNational Institutes of Health
  5. Novel diagnostic biomarker reference standards for newborn screening of Mucopolysaccharidoses type I and II.

    SBC: GELBCHEM, LLC            Topic: NICHD

    Project Summary The goal of this project is to design and prepare diagnostic biomarker reference standards for the endogenous glycosaminoglycan (GAG) Mucopolysaccharidosis type I (MPS-I) and type II (MPS- II) biomarkers. MPS-I and MPS-II are lysosomal storage disorders (LSDs) which are listed on the Recommended Uniform Screening Panel (RUSP) in the United States and are included in global Newborn ...

    STTR Phase I 2023 Department of Health and Human ServicesNational Institutes of Health
  6. Multispectral Sensor for Chemical Composition Analysis of Ultrafine Aerosols in Air Quality Assessment

    SBC: SPECTREE INC.            Topic: R

    Project SummaryWe propose developing and validating a novel platform technology that combines the collection and chemical analysis of ultrafine particles using an in-situ multispectral technique. The sample, collected directly onto the analysis substrate, is analyzed via excitation-emission matrix (EEM) spectroscopy. This approach will be validated against laboratory combustion-generated aerosols, ...

    STTR Phase II 2023 Department of Health and Human ServicesNational Institutes of Health
  7. Safety and Tolerability of TASIS-Peanut (Targeted Allergen Specific Immunotherapy within the Skin) patch for the Treatment of Peanut Allergy

    SBC: MOONLIGHT THERAPEUTICS, INC.            Topic: NIAID

    The following contains proprietary/privileged information that Moonlight Therapeutics requests not be released to persons outside the government, except for purposes of review and evaluation Safety and Tolerability of TASIS-Peanut (Targeted Allergen Specific Immunotherapy within theSkin) patch for the Treatment of Peanut Allergy Food allergies affect 30 million people in the USA and 17 million in ...

    SBIR Phase I 2023 Department of Health and Human ServicesNational Institutes of Health
  8. iKinnect Mobile Technology to Reduce Teen Substance Misuse and Health Disparities

    SBC: EVIDENCE-BASED PRACTICE INSTITUTE, INC.            Topic: NIDA

    PROJECT SUMMARY/ABSTRACTAdolescent substance abuse (SA) has been called America’s #1 public health problem, affecting as many as 16% of all youth under age 18 and often resulting in serious consequences such as criminal involvement, health problems, and suicide. Given that adolescent SA is associated with high rates of comorbidity with mental health (MH) problems and increased suicide risk, inte ...

    SBIR Phase I 2023 Department of Health and Human ServicesNational Institutes of Health
  9. Expansion and validation of novel mobile app for guiding home modifications for aging in place

    SBC: HomesRenewed Ventures LLC            Topic: R

    PROJECT SUMMARY In this Phase II SBIR, HomesRenewed Ventures, LLC (HRV Washington, DC) will build on our previous efforts to expand and validate an interactive mobile application (APP) for guiding home modifications (environmental interventions) critical to Aging in Place (AiP). Home modifications (HM) are associated with falls preventions, improved activities of daily living (ADLs), and emotional ...

    SBIR Phase II 2023 Department of Health and Human ServicesNational Institutes of Health
  10. Multiplexed biosensor for personal wildfire exposure assessment

    SBC: DL ADV-TECH, LLC            Topic: R

    Summary/Abstract: Wildfire are becoming more frequently and severe due to climate change, resulting in growing exposures of major population to high level of benzene and polycyclic aromatic hydrocarbons from biomass-burning emissions. Wildfire exposure pose a serious threat to the health and the well-being of humans. Currently, assessment of personal exposure to wildfire is dependent on taking env ...

    SBIR Phase I 2023 Department of Health and Human ServicesNational Institutes of Health
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