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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until April, 2020.

  1. Topic 364: SysMet: Integrative Systems Metabolomics

    SBC: OmicsCraft LLC            Topic: NCI

    Metabolomics plays an indispensable role in the growing systems biology approaches to identify reliable cancer biomarkers. Liquid chromatography coupled to mass spectrometry (LC-MS) and gas chromatography coupled to mass spectrometry (GC-MS) have been extensively used for high-throughput comparison of the levels of thousands of metabolites among biological samples. However, the potential values of ...

    SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  2. Topic 377: Symptom Management and Intervention Roadmaps (STaIRS)

    SBC: Carevive Systems, Inc.            Topic: NCI

    Numerous adverse symptoms are under-detected in cancer care resulting1-3 in missed opportunities for intervention; leading to poor treatment adherence, avoidable hospitalizations, and worse morbidity and survival. The IOM proposed shaking up the current symptom paradigm from reactive to proactive, personalized, technology-enabled models of symptom care as a solution to this clinical quality crisis ...

    SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  3. Topic 376: Non-Invasive Subtyping of Aggressive Tumor and Its Environment- Moonshot

    SBC: INLIGHTA BIOSCIENCES L.L.C.            Topic: NCI

    Generation of high-resolution 3D anatomic and dynamic images without exposing patients to ionizing radiation renders MRI the preferred imaging modality for the detection of tumor extent and treatment response to neo-adjuvant and adjuvant medical therapies. The goal of this proposal is to develop a non-invasive, in vivo imaging-based platform that can repeatedly generate three-dimensional molecular ...

    SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  4. Discriminating viral and bacterial meningitis infections with iDDS probes

    SBC: GENETAG TECHNOLOGY, INC.            Topic: NIAID

    Discriminating viral and bacterial meningitis infections with iDDS probes Confidential PI Shafer David A PhD PROJECT SUMMARY Rapid and accurate molecular diagnostics assays empower physicians to make informed treatment decisions especially when a disease state may result from variable causes that are indeterminable without such testing Meningitis may be caused by infection with microorganism ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  5. A novel biomaterial based therapy utilizing auto antigen and adjuvant for the amelioration of Type Diabetes

    SBC: ONEVAX, LLC            Topic: NIAID

    Immune mediated diseases such as type diabetes T D multiple sclerosis rheumatoid arthritis and systemic lupus erythematosis are reaching epidemic proportions in the US T D affects an estimated million Americans with more than new patients diagnosed annually resulting in roughly $ B in health care costs in the US each year T D is an autoimmune disease characterized by effector ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  6. An interactive App to Promote Safe and Effective use of Opioids in Young Children Postoperatively

    SBC: ARCHIE MD INC.            Topic: NIDA

    In recent years increased attention to pain in children and adolescents has led to a recent fold increase in opioid prescriptions Unsurprisingly the annual rates of analgesic related adverse drug events AR ADEs have soared to include andgt hospital admissions and hundreds of accidental overdose deaths in children and adolescents and has remained a significant problem At the heart of ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  7. Biomaterial based delivery of Interleukin to Regulatory T Cells for the amelioration of Type Diabetes

    SBC: ONEVAX, LLC            Topic: NIAID

    Type Diabetes T D results from a breakdown of self tolerance that is characterized by immune cell mediated destruction of the insulin producing cells in the pancreas Ultimately glucose metabolism is interrupted resulting in the development of life threatening complications such as heart disease and renal failure T D affects an estimated million Americans with more than new patie ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  8. Preclinical Evaluation of Ancestral Coagulation Factor VIII

    SBC: EXPRESSION THERAPEUTICS LLC            Topic: NHLBI

    ABSTRACT The development of transformative therapeutics including the possibility of a cure though gene therapy is the sole mission of Expression Therapeutics and continues to be a major research and development activity in the overall $ B USD hemophilia market space However progress in the field has been limited by significant hurdles including the size complexity instability immunogenic ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  9. Media based youth e cig prevention toolkit for community based organizations

    SBC: KDH Research And Communication, Inc.            Topic: NIDA

    KDH Research andamp Communication KDHRC submits this Fast Track SBIR proposal to develop and evaluate AVOID Anti Vaping Online Information Dissemination a media based online toolkit to support community based organizations CBO prevention programming against youth e cigarette e cig use Youth e cig use also known as vaping is a rapidly growing public health threat with use among hi ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  10. Novel sanitizer against viral infections with long lasting effect

    SBC: CAMELLIX, LLC            Topic: NIAID

    Project Summary Abstract Despite mandatory use of hand sanitizer on cruise ships there are reported cruise ship onboard norovirus outbreaks in exceeded the number of norovirus outbreaks outbreaks onboard cruise ships in One of the problems of currently available alcohol based hand sanitizer is that alcohol evaporates in less than seconds after each application to a surface ...

    STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health

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