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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until April, 2020.

  1. Topic 364: SysMet: Integrative Systems Metabolomics

    SBC: OmicsCraft LLC            Topic: NCI

    Metabolomics plays an indispensable role in the growing systems biology approaches to identify reliable cancer biomarkers. Liquid chromatography coupled to mass spectrometry (LC-MS) and gas chromatography coupled to mass spectrometry (GC-MS) have been extensively used for high-throughput comparison of the levels of thousands of metabolites among biological samples. However, the potential values of ...

    SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  2. Topic 376: Non-Invasive Subtyping of Aggressive Tumor and Its Environment- Moonshot

    SBC: INLIGHTA BIOSCIENCES L.L.C.            Topic: NCI

    Generation of high-resolution 3D anatomic and dynamic images without exposing patients to ionizing radiation renders MRI the preferred imaging modality for the detection of tumor extent and treatment response to neo-adjuvant and adjuvant medical therapies. The goal of this proposal is to develop a non-invasive, in vivo imaging-based platform that can repeatedly generate three-dimensional molecular ...

    SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  3. Discriminating viral and bacterial meningitis infections with iDDS probes

    SBC: GENETAG TECHNOLOGY, INC.            Topic: NIAID

    Discriminating viral and bacterial meningitis infections with iDDS probes Confidential PI Shafer David A PhD PROJECT SUMMARY Rapid and accurate molecular diagnostics assays empower physicians to make informed treatment decisions especially when a disease state may result from variable causes that are indeterminable without such testing Meningitis may be caused by infection with microorganism ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  4. Laboratory Bench Top EXAFS with STJ Spectrometer

    SBC: STAR CRYOELECTRONICS LLC            Topic: 100

    Project Summary Extended X ray absorption fine structure EXAFS is a technique that gives element specific structural and chemical information about molecules EXAFS currently requires bright X ray beams from specialized synchrotron light sources for most samples and so its applications are limited by access to these facilities This project will involve improved X ray detectors based on superco ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  5. Comprehensive Eye Evaluation Algorithm CEEvA

    SBC: Visionquest Biomedical LLC            Topic: M

    Summary The objective of this project is to develop the Comprehensive Eye Evaluation Algorithm CEEvA a system to achieve blindness prevention in a cost effective way CEEvA uses fundus images and available personal medical data in the electronic medical record medical history and laboratory tests to automatically screen not only for DR but also for POAG and AMD in populations at higher risks ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  6. Preclinical Evaluation of Ancestral Coagulation Factor VIII

    SBC: EXPRESSION THERAPEUTICS LLC            Topic: NHLBI

    ABSTRACT The development of transformative therapeutics including the possibility of a cure though gene therapy is the sole mission of Expression Therapeutics and continues to be a major research and development activity in the overall $ B USD hemophilia market space However progress in the field has been limited by significant hurdles including the size complexity instability immunogenic ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  7. Media based youth e cig prevention toolkit for community based organizations

    SBC: KDH Research And Communication, Inc.            Topic: NIDA

    KDH Research andamp Communication KDHRC submits this Fast Track SBIR proposal to develop and evaluate AVOID Anti Vaping Online Information Dissemination a media based online toolkit to support community based organizations CBO prevention programming against youth e cigarette e cig use Youth e cig use also known as vaping is a rapidly growing public health threat with use among hi ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  8. Novel sanitizer against viral infections with long lasting effect

    SBC: CAMELLIX, LLC            Topic: NIAID

    Project Summary Abstract Despite mandatory use of hand sanitizer on cruise ships there are reported cruise ship onboard norovirus outbreaks in exceeded the number of norovirus outbreaks outbreaks onboard cruise ships in One of the problems of currently available alcohol based hand sanitizer is that alcohol evaporates in less than seconds after each application to a surface ...

    STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  9. Anti CCL mAb to treat castration resistant prostate cancer

    SBC: JYANT Technologies, Inc.            Topic: 102

    Metastatic castration resistant prostate cancer CRPC PCa accounts for of PCa deaths and is associated with skeletal metastases CRPC affects patients differently making this disease difficult for physicians to provide standardized treatments with similar outcomes Docetaxel can prolong the overall survival in patients with metastatic CRPC but current therapies do not provide a cure Doce ...

    STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  10. Engineering probiotics to biosynthesize natural substances for microbiome brain research

    SBC: HGG Research LLC            Topic: R

    PROJECT SUMMARY To advance microbiome brain studies the general goals of this collaborative proposal are to provide services to research community by engineering probiotics e g E coli Nissle EcN Bifidobacteria longum Lactobacillus plantarum to biosynthesize various naturally occurring chemicals as prebiotic probiotic conjugates which will be marketed as important laboratory agents ...

    STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health

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