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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until April, 2020.

  1. Topic 364: SysMet: Integrative Systems Metabolomics

    SBC: OmicsCraft LLC            Topic: NCI

    Metabolomics plays an indispensable role in the growing systems biology approaches to identify reliable cancer biomarkers. Liquid chromatography coupled to mass spectrometry (LC-MS) and gas chromatography coupled to mass spectrometry (GC-MS) have been extensively used for high-throughput comparison of the levels of thousands of metabolites among biological samples. However, the potential values of ...

    SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  2. SBIR TOPIC 096: Novel Biodegradable Metal Stents for Neonatal Aortic Coarctation

    SBC: PediaStent LLC            Topic: NHLBI

    Most stents used to repair congenital heart lesions only need to serve as temporary scaffoldingsBecause pediatric patients have growing cardiovascular structuresthere is great interest in use of bioresorbable stentsBRSfor the treatment of coarctation of the aorta in neonatesA pediatric bioresorbable stent would allow thousands of infants each year to avoid the morbidity and mortality of more invas ...

    SBIR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health
  3. Localized Statin Delivery for Prevention of Primary AV Fistula Failure

    SBC: AFFINITY THERAPEUTICS, LLC            Topic: NHLBI

    Abstract Summary Arteriovenous fistulas AVFs are the preferred vascular access mode for hemodialysis patients but of AVFs fail to mature and only of mature AVFs are patent after year Vascular access failure including AVFs results from neointimal hyperplasia and contributes to andgt $ billion USD annual costs from vascular access failure including of hemodialysis patient hosp ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  4. HLS Durable Implantable Non Obstructive Venous Assist Device NOVAD for Support of Cavopulmonary Fontan Circulation

    SBC: Perfusion Solutions, Inc.            Topic: NHLBI

    Project Summary Abstract The proposal addresses NHLBI Topic of Special Interest HLS Development of mechanical circulatory support devices for individuals with congenital heart disease and single ventricle physiology after Fontan surgical palliation The design was specifically stimulated by the requirements outlined to Perfusion Solutions Inc PSI by pediatric and congenital surgeon Dr P ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  5. Testing and Commercialization of a Superior Device to Maintain Perioperative Normothermia In Anesthetized Patients

    SBC: Mercury Biomed LLC            Topic: 400

    Project Summary Abstract This proposal presents Phase of the plan of Mercury Biomed LLC for commercializing the new and innovative WarmSmart technology to more effectively keep patients warm during anesthetized surgery The WarmSmart technology is based on IP licensed from the University of Texas at Austin who is the academic partner for this STTR proposal WarmSmart embodies several breakthr ...

    STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  6. Software for OCT Analysis of Vascular Stents

    SBC: Dyad Medical, Inc.            Topic: NHLBI

    Software for OCT Analysis of Vascular Stents PI Ronny Shalev PhD Dyad Medical Summary Dyad Medical Inc will create intravascular OCT IVOCT software for clinical live time determination of stent apposition OCTivat live the live time OCT image visualization and analysis tool and for offline analysis of stent implantation OCTivat stent Every year s of thousands of patients in the US ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  7. A Novel Non Cytotoxic Epigenetic Therapeutic for Sickle Cell Disease

    SBC: DeNovoTherapies LLC            Topic: NHLBI

    ABSTRACT The goal of this Fast Track proposal is to develop a novel non cytotoxic epigenetic therapeutic for life long disease modification of sickle cell disease SCD SCD is a morbid life shortening condition caused by mutated hemoglobin sickle hemoglobin HbS The pathophysiology triggered by sickle hemoglobin is interrupted by another hemoglobin that the body usually produces in utero fe ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  8. Evolution of an Adaptable Prosthetic Foot Design for Normalization of Biomechanics During Community Participation

    SBC: OHIO WILLOW WOOD COMPANY, THE            Topic: NICHD

    Evolution of an Adaptable Prosthetic Foot Design for Normalization of Biomechanics During Community Participation Summary Abstract The vision of this project is to improve the functional physical mobility of people with lower extremity amputations so that they can more fully and confidently participate in a wider range of activities This will enhance their personal satisfaction thereby improving ...

    STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  9. Biocatalytic production of precursors to lutein and zeaxanthin to address age related macular degeneration

    SBC: EscaZyme Biochemicals, LLC            Topic: N

    Project Summary Atrophic dry age related macular degeneration AMD is the leading cause of severe loss of vision for those over age Dietary supplements containing lutein and zeaxanthin are recommended by the NEI for those at risk of late AMD There has been a corresponding growth in demand for these two xanthophylls Lutein and zeaxanthin are currently sourced from marigolds grown mostl ...

    STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  10. Immersive Virtual Reality as a Tool to Improve Police Safety in Adolescents and Adults with ASD

    SBC: Floreo, Inc.            Topic: 103

    Floreo Technology proposes to develop the Police Safety Module PSM an innovative immersive mobile virtual reality VR application designed to train police safety in adolescents and adults with autism spectrum disorder ASD ASD has been increasing in prevalence over recent years While much attention has been paid to the causes and early diagnosis of ASD there remains a clear need for effec ...

    STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health

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