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The Award database is continually updated throughout the year. As a result, data for FY23 is not expected to be complete until September, 2024.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Concurrent Aerobic Exercise and Cognitive Training to Prevent Alzheimer's in at-risk Older Adults

    SBC: MOAI TECHNOLOGIES, LLC            Topic: NIA

    Project Summary/Abstract Alzheimer’s disease (AD) affects more than six million Americans currently and is projected to affect 14 million at a cost of $1.2 trillion in 2050. Despite its tremendous impacts and the limited influence of pharmacological therapies, attention has been brought to non-pharmacological interventions as promising therapeutic strategies for the prevention of cognitive decli ...

    SBIR Phase II 2023 Department of Health and Human ServicesNational Institutes of Health
  2. Using Structured Light Sensing with Machine Learning to Detect Unwitnessed In-Home Falls

    SBC: Applied Universal Dynamics, Corp.            Topic: NIA

    Project Summary/Abstract Older adults are disproportionately affected by falls. Older adults who have memory loss (mild to moderate cognitive impairment) can forget to wear wireless alert pendants or wristbands that are used in case they fall in their home. Falls among adults 65 and older caused over 34,000 deaths in 2019, making it the leading cause of injury death for that group. Older adult fal ...

    SBIR Phase II 2023 Department of Health and Human ServicesNational Institutes of Health
  3. Cue-induced drug craving monitoring for opioid use disorder with visual evoked potentials

    SBC: NEUROTYPE INC.            Topic: NIDA

    Project Summary / Abstract More than 2 million people in the United States have an Opioid Use Disorder (OUD). Overall, at least half of the treatment-seeking population relapse, contributing to over 75,000 overdose deaths annually. The purpose of this SBIR Fast-Track application is to create a regulated device to objectively monitor Cue-Induced Craving (CIC) in Opioid Use Disorder (OUD) patients. ...

    SBIR Phase I 2023 Department of Health and Human ServicesNational Institutes of Health
  4. Enabling rapid and effective stroke thrombectomy procedures from a Transradial approach: Combining introducer sheath, guide catheter, and distal access catheter into a single device.

    SBC: PIRAEUS MEDICAL, INC.            Topic: 100

    PROJECT SUMMARY/ABSTRACT This proposal will improve the care of patients suffering from Acute Ischemic stroke (AIS). Catheter-based thrombectomy has been established as the standard treatment for AIS. Still, substantial limitations remain: lt50% of patients achieve first-pass clot clearance, the best predictor of good neurological outcome, largely due to shortcomings in the approach (transfemoral ...

    SBIR Phase II 2023 Department of Health and Human ServicesNational Institutes of Health
  5. Systemic Transplantation of MyoPAXon: IND Enabling Studies for the Treatment of DMD

    SBC: MYOGENICA INC.            Topic: NIAMS

    PROJECT SUMMARY Duchenne muscular dystrophy (DMD) is the most common type of muscular dystrophy, caused due to mutations in the dystrophin gene. DMD is characterized by progressive muscle wasting and overall loss of muscle function. DMD patients become wheel chair dependant by 12 years of age and the associated cardiorespiratory complications result in their early death around 20 years of age. Dys ...

    STTR Phase I 2023 Department of Health and Human ServicesNational Institutes of Health
  6. Inter-alpha Inhibitors in Experimental Necrotizing Enterocolitis

    SBC: PROTHERA BIOLOGICS, INC.            Topic: NICHD

    Necrotizing enterocolitis (NEC) is a devastating acute inflammatory condition of the gastrointestinal tract resulting in intestinal necrosis, systemic sepsis and multi-system organ failure found mostly in infants born prematurely. Despite modern medical advances in the past decade, the etiology remains elusive and morbidity and mortality are still unacceptably high. It has been concluded that the ...

    SBIR Phase I 2023 Department of Health and Human ServicesNational Institutes of Health
  7. Two-for-one Stroke Thrombectomy:A novel Dual DAC to enhance navigability, lumen size, aspiration efficiency, and persistent flow arrest in mechanical thrombectomy

    SBC: PIRAEUS MEDICAL, INC.            Topic: 105

    PROJECT SUMMARY/ABSTRACT The long-term goal of this proposal is to improve the care of patients suffering from Large Vessel Occlusion Acute Ischemic stroke. Currently, mechanical thrombectomy techniques can achieve revascularization in over 70% of cases, and physicians are rapidly adoption aspiration thrombectomy over stent-trievers. Aspiration maintains equivalent angiographic and clinical outcom ...

    STTR Phase I 2023 Department of Health and Human ServicesNational Institutes of Health
  8. Prodrugs of potent and selective protease inhibitors as tauopathy therapeutics

    SBC: MYRIEL, INC.            Topic: 105

    PROJECT ABSTRACT Myriel, Inc., is a pharmaceutical start-up company founded in 2022 to find cures for tauopathies, including Alzheimer’s disease and related dementias (ADRD), which impair cognition in 32% of US adults 65 years and older. The goal of this Phase 1 STTR application is to provide Myriel with a brain-penetrant analogue of our lead compound, GPHR ‘739, the first potent, selective, r ...

    STTR Phase I 2023 Department of Health and Human ServicesNational Institutes of Health
  9. Novel warming and massaging bra for improved breast milk expression

    SBC: Momease Solutions, Inc.            Topic: NICHD

    PROJECT SUMMARY Breast milk is an unmatched bioactive source of nutritional, immunological, and neurodevelopmental benefits for infants that evolves as an infant grows to meet their unique health and nutritional needs. As such, breast milk is considered the clinical gold standard for infant feeding, and both the American Academy of Pediatrics (AAP) and the World Health Organization (WHO) recommend ...

    SBIR Phase I 2023 Department of Health and Human ServicesNational Institutes of Health
  10. A software tool to facilitate variable-level equivalency and harmonization in research data: Leveraging the NIH Common Data Elements Repository to link concepts and measures in an open format

    SBC: ALGENTA TECHNOLOGIES LLC            Topic: R

    Abstract The National Institute on Aging (NIA) supports numerous studies and archives that collect and disseminate critical data about the aging population of the United States. By supporting the collection and dissemination of longitudinal and multidisciplinary data, the NIA provides researchers the opportunity to measure change and stability in individuals over time, as well as to investigate ag ...

    SBIR Phase I 2023 Department of Health and Human ServicesNational Institutes of Health
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