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Award Data
The Award database is continually updated throughout the year. As a result, data for FY23 is not expected to be complete until September, 2024.
Download all SBIR.gov award data either with award abstracts (290MB)
or without award abstracts (65MB).
A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.
The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.
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Microbial Synthesis of Therapeutic Bile Acids for Alzheimer's Disease
SBC: Metselex, Incorporated Topic: 105ABSTRACT This Phase STTR Phase II proposal aims to engineer and scale-up a synthetic metabolic pathway in a microbial host to produce UDCA and related compounds. Additionally, the UDCA produced from the engineered synthetic metabolic pathway will be used to synthesize derivatives for testing in our Alzheimer’s Disease cell and animal models. The proposed work has high intellectual merit for the ...
STTR Phase II 2023 Department of Health and Human ServicesNational Institutes of Health -
Expansion and validation of novel mobile app for guiding home modifications for aging in place
SBC: HomesRenewed Ventures LLC Topic: RPROJECT SUMMARY In this Phase II SBIR, HomesRenewed Ventures, LLC (HRV Washington, DC) will build on our previous efforts to expand and validate an interactive mobile application (APP) for guiding home modifications (environmental interventions) critical to Aging in Place (AiP). Home modifications (HM) are associated with falls preventions, improved activities of daily living (ADLs), and emotional ...
SBIR Phase II 2023 Department of Health and Human ServicesNational Institutes of Health -
Novel Post-surgical Incision Management Device to Prevent Ostomy Complications
SBC: FISTULA SOLUTION CORPORATION Topic: 102Project Summary/Abstract Over 100,000 patients of all ages undergo ostomy surgery in the United States (US) annually due to a variety of pathophysiologic conditions including colorectal cancer, inflammatory bowel disease (Crohn’s disease and ulcerative colitis), bowel obstruction, diverticulitis, and many other medical conditions. Ostomy surgery may also be necessary in cases of severe abdominal ...
SBIR Phase II 2023 Department of Health and Human ServicesNational Institutes of Health -
Concurrent Aerobic Exercise and Cognitive Training to Prevent Alzheimer's in at-risk Older Adults
SBC: MOAI TECHNOLOGIES, LLC Topic: NIAProject Summary/Abstract Alzheimer’s disease (AD) affects more than six million Americans currently and is projected to affect 14 million at a cost of $1.2 trillion in 2050. Despite its tremendous impacts and the limited influence of pharmacological therapies, attention has been brought to non-pharmacological interventions as promising therapeutic strategies for the prevention of cognitive decli ...
SBIR Phase II 2023 Department of Health and Human ServicesNational Institutes of Health -
Development of novel therapeutics for cancer cachexia
SBC: EMMYON, INC. Topic: NCIPROJECT SUMMARY / ABSTRACT Cancer-induced skeletal muscle atrophy is a central and defining feature of the cancer cachexia syndrome, a highly prevalent condition that affects over 50% of patients with advanced cancer and over 500,000 patients per year in the U.S. In addition to being highly prevalent, cancer-induced skeletal muscle atrophy has devastating consequences for patients; it reduces phys ...
SBIR Phase II 2023 Department of Health and Human ServicesNational Institutes of Health -
Point-of-care lateral flow immunoassay for diagnosis of pertussis
SBC: DXDISCOVERY INC Topic: NIAIDPertussis (Whooping cough) is a highly contagious, airborne disease that is rapidly re-emerging as a serious public health threat in the United States. Despite high vaccine coverage, annual reported cases in the U.S. have been increasing recently, with an average of 25,000 per year from 2010-2019. This is a level unseen since the early 1960s. Diagnosis of pertussis is challenging because its early ...
SBIR Phase II 2023 Department of Health and Human ServicesNational Institutes of Health -
Optimization of an integrin enhancing molecule for the treatment of Duchenne muscular dystrophy
SBC: STRYKAGEN CORPORATION Topic: 100Abstract Duchenne Muscular Dystrophy (DMD) is a fatal muscle disease with an incidence of 1 in 5000 males. DMD results from mutations in the gene encoding dystrophin, a 427 kDa scaffolding protein responsible for providing a mechanical link between the muscle fiber actin cytoskeleton and laminin in the extracellular matrix. The α7β1 integrin is a transmembrane linkage system in skeletal and card ...
SBIR Phase II 2023 Department of Health and Human ServicesNational Institutes of Health -
Treating non-small cell lung tumors with a novel inhaled dry powder chemotherapeutic formulation
SBC: Quench Medical Inc. Topic: 102Project Summary / Abstract Significance Lung cancer is the leading cause of cancer mortality with a 5-year survival rate of less than 20% following standard of care therapy. Problem Despite the use of aggressive surgery, combination chemotherapy and immunotherapy, a major limitation in the control of primary and metastatic non-small cell pulmonary tumors with the use of the systemic administration ...
SBIR Phase II 2023 Department of Health and Human ServicesNational Institutes of Health -
Simulation and Education Tool for Physical Examinations of Orthopedic Pathologies
SBC: INNOVATIVE DESIGN LABS INC Topic: NIAMSProject Summary/Abstract The proposed project focuses on creating a simulation system that provides hands-on skills training of musculoskeletal, soft tissue, and ligament function for medical and health science students. Significance: Musculoskeletal (MSK) disorders are the most frequent chronic health problems in the United States. Despite this reality, education in the prevention, diagnosis, and ...
SBIR Phase II 2023 Department of Health and Human ServicesNational Institutes of Health -
Automated Long-Term Oxygen Therapy Control System
SBC: Minnesota HealthSolutions Corporation Topic: NHLBIProject Summary/Abstract This proposed project relates to the development and evaluation of a novel closed-loop long-term oxygen therapy control system that includes an innovative smartphone-based companion software application. We hypothesize that such a system will optimize oxygen delivery in mobile patients, minimize hypoxemia and air hunger during physical exertion, avoid hyperoxia and improve ...
SBIR Phase II 2023 Department of Health and Human ServicesNational Institutes of Health