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The Award database is continually updated throughout the year. As a result, data for FY23 is not expected to be complete until September, 2024.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Accurate WiFi-Based Localization of Dementia Patients For Caregiver Support

    SBC: ASTER LABS, INC.            Topic: NIA

    DESCRIPTION (provided by applicant): An estimated 5.4 million Americans had Alzheimer's disease in 2012 and a 50% increase in this number is expected by 2030. The majority of these patients (70%) will live at home where they receive 75% of their care frominformal caregivers, unpaid individuals such as family members, friends, and neighbors. These caregivers provide valuable services, often a ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  2. Potassium Level Monitoring System

    SBC: ADVANCED MEDICAL ELECTRONICS CORP            Topic: NIA

    DESCRIPTION (provided by applicant): Advanced Medical Electronics (AME) and our partners propose a minimally-invasive system for continuous monitoring of potassium. Measurement of blood levels of potassium is important in clinical medicine. Abnormalities of potassium, common in heart and kidney disease, can be aggravated by many medications used to treat these disorders leading to arrhythmias and ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  3. An immunomodulatory yeast-derived beta glucan as a component of a conjugate

    SBC: BIOTHERA            Topic: NIAID

    DESCRIPTION (provided by applicant): Fungal infections, particularly in immunocompromised patients, are a serious and growing problem. Although antifungal therapeutics have improved greatly, failures and relapse are common. Aspergillus fumigatus is a primary cause of these infections in several patient populations: transplants, leukemics, genetic deficiencies such as chronic granulomatous disease ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  4. Orthopedic Tissue Tension Sensor

    SBC: FOCUSSTART, LLC            Topic: NIAMS

    DESCRIPTION (provided by applicant): In orthopedic surgery, surgeons have to handle not only bone but also the surrounding soft tissue, including muscle, fascia, tendon, ligament and capsule. Successful handling of these tissues is often the key to high reproducibility, good soft tissue healing, and restoration of overall function. However, there are no widely used, robust methods for intra-opera ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  5. Calcaftor, a CFTR stabilizer for Cystic Fibrosis treatment

    SBC: CALISTA THERAPEUTICS INC            Topic: NIDDK

    DESCRIPTION (provided by applicant): Calista Therapeutics has invented Calcaftor, a first-in-class peptide drug that can treat all Cystic Fibrosis (CF) patients. Calcaftor is validated in the gold standard pre-clinical model of CF using F508 -CFTR lung tissue harvested from CF transplant patients. Results from this model demonstrated a gt25 hour duration of action that enables once daily inhaled n ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  6. Infrared Eyes

    SBC: EDEN MEDICAL, INC.            Topic: NIDDK

    DESCRIPTION (provided by applicant): Eden Medical, Inc. is pleased to submit this Phase 1 SBIR proposal to develop the Infrared Eyes (iREyes) imager system, an affordable and powerful mobile health (mhealth) tool for healthcare. The hand-held iREyes system will acquire both thermal and visible spectrum imagery to quantify healing via foot thermal indexing methodology. The iREyes will offer a use ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  7. Magnetic Tracking and Orientation of Imaging Endoscopic Capsules

    SBC: Koronis Biomedical Technologies Corp.            Topic: NIDDK

    DESCRIPTION (provided by applicant): Prior to the advent of capsule endoscopes (CE), imaging and examination of the small bowel was difficult. Today, a patient swallows the capsule with an imaging camera, which is then carried passively through the gastrointestinal (GI) tract by peristalsis. The onboard camera captures images of the lumen wall several times per second over a 7-11 hour period, rela ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  8. Development of a porcine model of polycystic kidney disease by multiplex gene-editing.

    SBC: Recombinetics, Inc.            Topic: NIDDK

    ? DESCRIPTION (provided by applicant): Polycystic kidney diseases (PKD) are a group of inherited disorders characterized by progressive cyst development in the kidney resulting in bilateral renal enlargement and often end stage renal disease (ESRD). The most common form of PKD, autosomal dominant PKD occurs at a frequency of 1:400 to 1:1000. Currently, there is no treatment that can slow or re ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  9. Intraocular Aerosol Treatment for Inhibition of Proliferative Vitreoretinopathy

    SBC: MSP CORPORATION            Topic: NEI

    Project Summary Proliferative vitreoretinopathy (PVR) is a major complication of retinal detachments and is responsible for most of the failures in retinal reattachment surgeries. About 10% of retinal detachment patients suffer from PVR. These patients often have poor visual outcome despite multiple surgeries. Our previous work on inhibition of PVR has focused on pharmacological intervention concu ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  10. Retinal Prosthesis with Enhanced Thermal Imaging

    SBC: ADVANCED MEDICAL ELECTRONICS CORP            Topic: NEI

    DESCRIPTION (provided by applicant): We propose to develop and evaluate the utility of a thermal imaging system as an input modality to a retinal prosthetic. Retinal prostheses restore partial vision to people blinded by outer retinal degenerative diseasessuch as Retinitis Pigmentosa (RP) or Macular Degeneration. The Argus II Retinal Prosthesis System is intended to provide electrical stimulation ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
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