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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until April, 2020.

  1. Topic 364: SysMet: Integrative Systems Metabolomics

    SBC: OmicsCraft LLC            Topic: NCI

    Metabolomics plays an indispensable role in the growing systems biology approaches to identify reliable cancer biomarkers. Liquid chromatography coupled to mass spectrometry (LC-MS) and gas chromatography coupled to mass spectrometry (GC-MS) have been extensively used for high-throughput comparison of the levels of thousands of metabolites among biological samples. However, the potential values of ...

    SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  2. A user friendly point of care device for G PDH determination

    SBC: ANALYTICAL DIAGNOSTICS SOLUTIONS            Topic: NIAID

    Malaria caused by Plasmodium vivax threatens over billion people globally and sickens tens of millions annually Radical cure for P vivax malaria includes therapy aimed both at the acute attack blood schizontocidal and against future attacks hypnozoitocidal The only hypnozoitocide available are aminoquinolines such as primaquine or tafenoquine However clinicians often do not prescribe ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  3. Interstitial Intensity Modulated Photodynamic Therapy i IMPDT

    SBC: SIMPHOTEK, INC.            Topic: 102

    Over worldwide cases of head and neck Handamp N cancer occur annually Despite aggressive treatment about of Handamp N cancers recur and progress Recent studies of interstitial PDT I PDT have shown promising results in the treatment of patients with locally advanced Handamp N cancer that fail standard therapies I PDT provides a means to treat cancerous tumors while minimizing da ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  4. Improved cleaning technology for reducing risk of transmitting infection in endoscopy

    SBC: ADVANCED BIODEVICES, LLC            Topic: NIAID

    Project Summary Abstract More than million procedures were performed with GI endoscopic devices in Since endoscopes cannot be sterilized risk of infection from contaminated endoscopes can be tangible and needs to be urgently addressed Infection at endoscopy has recently been recognized as a significant risk after two patient deaths from CRE infection transmitted by contaminated duodenos ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  5. Soluble E NTPDase for sepsis

    SBC: Purine Pharmaceuticals Inc.            Topic: NIGMS

    SUMMARY Sepsis is a medical condition caused by an overwhelming systemic inflammatory response to infection Although the underlying infection can now be efficiently treated with antibiotics there are no effective therapies to control the organ damage caused by the inflammatory response of the host As a result sepsis is the leading cause of mortality in intensive care units and is the tenth lea ...

    STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  6. Protein therapeutic to facilitate healing of chronic wounds

    SBC: TRIM-EDICINE, INC.            Topic: 300

    Project Summary This Phase I SBIR proposal targets the development of recombinant human MG rhMG a novel tissue repair protein as a topical therapeutic candidate to facilitate healing of chronic wounds Wound care represents a challenging problem to the public health as no effective treatments for chronic non healing wounds are available MG is an essential component of the cell membrane ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  7. Amplification Free Target Enrichment and Direct Sequencing of Large Chromosomal Segments

    SBC: GENERATION BIOTECH, LLC            Topic: 172

    This project develops a platform independent target enrichment technology for the preparation of large kb DNA fragments These are magnetically selected from genomic regions of interest and used directly without any intermediate amplification step for next generation sequencing NGS This will allow the direct detection of methylated base information on several of the newer NGS sys ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  8. Large Volume Visceral Fat Removal to Reverse Insulin Resistance in Type Diabetes

    SBC: Medality Medical, LLC            Topic: 200

    Abstract Excess visceral fat VF has been strongly linked with development of insulin resistance and subsequent type diabetes T DM in humans and rodent lipectomy studies have demonstrated that this relationship is causal Among the nearly million US adults affected by T DM disease onset typically appears secondary to weight gain with excess VF considered to be a major driver Lifestyle ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  9. Novel Augmented Reality Training System for HAZOPS Training

    SBC: CELL PODIUM LLC            Topic: 142

    Summary Abstract Cell Podium proposes to develop in collaboration with the Rutgers School of Public Health RSPH Office of Public Health Practice OPHP an augmented reality training system for realistic hazardous operations training experiences The system consists of physical hazard props identified by Bluetooth beacons and a location aware mobile phone application that simulates a sensor u ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  10. Method for High Throughput Assembly of Long DNA Fragments in vitro

    SBC: PHARMASEQ, INC            Topic: 200

    SUMMARY The main project goal is to develop principles and demonstrate the feasibility of a fast in vitro method that will increase the length of synthetic double stranded DNA from its current limit of about kb to kb This in turn will facilitate the ability to more rapidly create artificial genes and chromosomes and thus become an important tool in synthetic biology The proposed approac ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health

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