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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until April, 2020.

  1. VIRTUAL REALITY FOR MOBILE PAIN CONTROL

    SBC: MEDIA REZ LLC            Topic: NIDA

    Under this Small Business Innovation Research SBIR Phase II project Topic the Contractor will produce anditeratively test a virtual reality VR intervention with diverse populations of patients with chronic pain The Contractorwill develop and refine VR content based on patient and clinician feedback develop and implement a plan forusing the VR content as a therapeutic tool in a ...

    SBIR Phase II 2017 Department of Health and Human ServicesNational Institutes of Health
  2. Multi Source E Beam kV X Ray Tube for Image Guided Radiotheraphy

    SBC: TELESECURITY SCIENCES, INC.            Topic: 102

    DESCRIPTION provided by applicant This project will develop a commercial product that will enable for the first time realtime tumor tracking during radiotherapy at an attractive price point and with minimal interference with standard clinical practice The key novel technology is an optimized multi source X ray tube with focal spots that is placed below the multi leaf collimator MLC of a r ...

    SBIR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health
  3. I Live Inspired Individually Tailored and Integrated Social Support Network for Tobacco Cessation

    SBC: Live Inspired, LLC            Topic: NIDA

    DESCRIPTION provided by applicant Smoking kills Americans annually exacerbates myriad diseases and costs billions in healthcare and productivity losses Numerous barriers exist to accessing traditional treatment e g costs traveling to and scheduling appointments other logistics Text messaging is an extremely popular communication method Over of all Americans use text m ...

    SBIR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health
  4. Characterization of a low mutation rate E coli in extended fermentation

    SBC: SCARAB GENOMICS, LLC            Topic: 200

    DESCRIPTION provided by applicant Scarab Genomics was founded to improve E coli as an industrial organism by genome engineering These strains have stable genomes since all prophages transposable and IS elements and the error prone repair systems were removed A recA version has always been provided as an option The goal of the Phase I project was to ascertain whether the changes already in ...

    SBIR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health
  5. Riboswitch Based Methyltransferase HTS Assay for Epigenetic Drug Discovery

    SBC: Bellbrook Labs, LLC            Topic: 300

    DESCRIPTION provided by applicant Epigenetic regulation of gene expression via methylation has been implicated in diverse diseases including cancer diabetes and inflammation and high throughput screening for histone methyltransferase HMT inhibitors is an area of intense drug discovery effort However there are significant shortcomings with existing HMT enzyme assay methods and these are s ...

    SBIR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health
  6. In Situ Autovaccination against Solid Cancers with Intratumoral Hiltonol Poly ICLC A phase II Adaptive Multicenter Clinical Study

    SBC: Oncovir            Topic: 102

    DESCRIPTION provided by applicant Hiltonol poly ICLC is a stabilized dsRNA therapeutic viral mimic or andapos danger signalandapos that activates multiple elements of innate and adaptive immunity It is a standalone immunomodulator but when properly combined with antigen it generates a comprehensive Th weighted immune response best suited for antiviral and antitumor action This project ...

    SBIR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health
  7. Accurate protein folding software to predict ligand induced conformational changes in G protein coupled receptors

    SBC: DNASTAR, INC.            Topic: 100

    Abstract In humans and animals G protein coupled receptors GPCRs are embedded on cell surfaces and function as key regulators of physiological events by transmitting signals from extracellular stimulants across the cell membrane into the cell Impaired or abnormal GPCR function can result in disordered physiological processes causing a broad and diverse range of diseases For this reason GPCRs ...

    SBIR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health
  8. Development of novel biophysically designed fluids for swallowing disorders

    SBC: Swallow Solutions, LLC            Topic: 600

    Swallowing disorders known as dysphagia are associated with increased mortality and morbidity including malnutrition dehydration pulmonary complications and reduced quality of life More than M adults and millions more children suffer from dysphagia This disorder commonly causes liquids whether overly thin water coffee or overly thickened to be aspirated or misdirected into the air ...

    SBIR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health
  9. IGF OT IGF VALIDATION OF MOBILE TECHNOLOGIES FOR CLINICAL ASSESSMENT

    SBC: Pro-Change Behavior Systems Inc            Topic: NCI

    Not Available

    SBIR Phase II 2015 Department of Health and Human ServicesNational Institutes of Health
  10. IGF OT IGF FY IWIN NAVIGATING YOUR PATH TO WELL BEING SBIR PHASE II BASE AWARD PERIOD OF PERFORMANCE

    SBC: Pro-Change Behavior Systems Inc            Topic: NIDA

    Not Available

    SBIR Phase II 2015 Department of Health and Human ServicesNational Institutes of Health

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