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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Biocatalytic production of precursors to lutein and zeaxanthin to address age related macular degeneration

    SBC: EscaZyme Biochemicals, LLC            Topic: N

    Project Summary Atrophic dry age related macular degeneration AMD is the leading cause of severe loss of vision for those over age Dietary supplements containing lutein and zeaxanthin are recommended by the NEI for those at risk of late AMD There has been a corresponding growth in demand for these two xanthophylls Lutein and zeaxanthin are currently sourced from marigolds grown mostl ...

    STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  2. Biological Treatment of Bacterial Keratitis

    SBC: AMEBAGONE INC            Topic: N

    Project Summary Abstract Bacterial keratitisBKis an infection of the cornea thatif left untreatedcan cause blindnessStaphylococcus aureusSaStreptococcus pneumoniaeSpand Pseudomonas aeruginosaPaare three major causes of BK in North AmericaSymptoms of BK include painrednessinflammationand opacity of the affected cornea and loss of visual acuityAmebaGone IncAGpartnered with UW Madison Department of O ...

    SBIR Phase II 2017 Department of Health and Human ServicesNational Institutes of Health
  3. A Novel Strategy to Identify Substances that Improve Mitochnodrial Fitness

    SBC: CYTEGEN CORP            Topic: NIA

    Project Summary Abstract Mitochondrial dysfunction causes mitochondrial diseases and is tightly linked to aging and neurodegenerative disorders such as Parkinsonandapos s and Alzheimerandapos s Recent discoveries support that mitochondrial dysfunction can be overcome to treat age related decline Cytegenandapos s hypothesis is that exercise induces the secretion of blood borne proteins that act ...

    STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  4. Development of a Photoacoustic Quantitative Ultrasound PAQUS device for clinical use

    SBC: IF, LLC            Topic: NIAMS

    Title Development of a Photoacoustic Quantitative Ultrasound PAQUS device for clinical use Abstract The objective of this program is to develop a highly innovative bone assessment device by combining our recently invented photoacoustic physio chemical analysis PAPCA technique with more established quantitative ultrasound QUA techniques After a clinic ready Photoacoustic Quantitative Ultra ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  5. Roboglasses electronic travel aid with hands free obstacle avoidance for blind and vision impaired users

    SBC: FAUXSEE INNOVATIONS LLC            Topic: N

    Project Summary Fauxsee Innovations LLC The objective of this project is to assess the efficacy and usability of an electronic travel aid ETA called Roboglasses developed through an NSF SBIR grant in reducing head and upper body injuries sustained by blind people who currently use a cane and or guide dog for mobility Canes and dogs only provide information about ground level obstructions ...

    STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  6. Immersive Virtual Reality as a Tool to Improve Police Safety in Adolescents and Adults with ASD

    SBC: Floreo, Inc.            Topic: 103

    Floreo Technology proposes to develop the Police Safety Module PSM an innovative immersive mobile virtual reality VR application designed to train police safety in adolescents and adults with autism spectrum disorder ASD ASD has been increasing in prevalence over recent years While much attention has been paid to the causes and early diagnosis of ASD there remains a clear need for effec ...

    STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  7. Large-Scale Production of High Purity Human Cortical Glutamatergic Neurons

    SBC: BrainXell, Inc            Topic: 101

    Project Summary AbstractThere exists a dire need for new and more effective drugs to treat disorders of the central nervous systemCNSespecially in mental healthThe pace of approval for new chemical entities is anemicwith an average of just three compounds per year entering the market over the lastyearsUnsurprisinglyclinical trial failure rates for CNS drug development remain greater thanand many m ...

    SBIR Phase II 2017 Department of Health and Human ServicesNational Institutes of Health
  8. Evidence-Based Pain Intervention for Veterans: Leveraging Mobile and Social Media

    SBC: Pro-Change Behavior Systems, Inc.            Topic: NCCIH

    Chronic musculoskeletal pain creates a significant public health burden, and Veterans are disproportionately affected. The frequency and extent of co-occurrence of pain and PTSD, pain and Traumatic Brain Injury (TBI), all three conditions (Post-deployment Multi-symptom Disorder (PMD), and other multi-symptom syndromes can complicate and reduce the effectiveness of pain treatment. Furthermore, the ...

    SBIR Phase II 2017 Department of Health and Human ServicesNational Institutes of Health
  9. Novel Antigen-Specific Immunomodulatory Tregitope-based Therapy to Address Autoimmune Pathogenesis in Graves' Disease

    SBC: EPIVAX, INC.            Topic: 200

    ABSTRACT SignificanceGravesdiseaseGDone of the most prevalent autoimmune diseasesis caused by stimulating autoantibodiesTSAbto the Thyroid Stimulating Hormone ReceptorTSHRresulting in hyperthyroidismCurrent methods for managing hyperthyroidism in GD target excess thyroid hormone secretion by ablation or removal of the thyroid or by blocking thyroid hormone synthesisEach of these therapies is assoc ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  10. Noninvasive Home Assessment of Cardiac Filling Pressure to Identify Heart Failure Patients at High Risk for Readmission

    SBC: Vixiar Medical, Inc            Topic: NHLBI

    Congestive heart failure CHF is the most common reason for hospitalization in the U S with over million admissions per year Patients admitted with CHF usually need IV diuretics to promote fluid removal The readmission rate is high over by days and by days post discharge This also presents an enormous economic burden hospitalizations account for a large percentage of the ...

    STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
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