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The Award database is continually updated throughout the year. As a result, data for FY20 is not expected to be complete until September, 2021.

  1. A Rapid Paper Strip Nucleic Acid Test for the Point of Care Detection of Zika virus

    SBC: Crosslife Technologies Inc.            Topic: NIAID

    A Rapid Paper Strip Nucleic Acid Test for the Point of Care Detection of Zika virus CrossLife Technologies Inc Project Summary Abstract There are unmet needs for nucleic acids new diagnostics that can be applied at the point of care to detect Zika Virus ZIKV infections A highly sensitive simple paper strip molecular test that detects ZIKV at the point of care will be developed The target seq ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  2. Direct sequencing of serum antibodies after infection

    SBC: MAPP BIOPHARMACEUTICAL, INC.            Topic: NIAID

    Project Summary Monoclonal antibodies mAbs are a well validated drug platform with exquisite specificity diversity and potency They offer the lowest risk class of drug for development through licensure and offer great potential for addressing emerging and re emerging infectious diseases To be prepared as threats like Ebola EBOV Marburg MARV and Zika viruses continue to emerge or re em ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  3. Digital serology for parallel parasitic disease detection

    SBC: Serimmune            Topic: NIAID

    The proposed project aims to build a diagnostic test for chronic T cruzi infection and Chagas disease that not only improves testing performance but that can be readily integrated with similarly developed tests for most clinically important parasitoses Current assays for Chagas disease and other parasitic infections lack desired levels of specificity and require multiple independent assays an ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  4. Development of polyvalent inactivated rhinovirus vaccine

    SBC: Meissa Vaccines Inc            Topic: NIAID

    Human rhinovirus RV is the predominant etiological agent of the common cold and the leading cause of human infectious disease RV is more than a nuisance It is a major cause of community acquired pneumonia in children and adults in the United States and plays a major role in triggering exacerbations of both asthma and chronic obstructive pulmonary disease resulting in billions of dollars in me ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  5. Deceased Donor Bone Marrow Salvage and Processing

    SBC: Ossium Health, Inc.            Topic: NIAID

    ABSTRACT This program aims to develop a method for banking clinical grade bone marrow from cadaveric donors that can be deployed nationally to ameliorate shortages provide bone marrow stockpiles as medical countermeasures for nuclear threats and support existing research approaches such as delayed immune tolerance induction and transfusion of HIV resistant stem cells We will adapt a method de ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  6. Nanowire Sensor based Assay for Detecting Dengue and Chikungunya Virus

    SBC: Innosense Llc            Topic: NIAID

    PROJECT SUMMARY The Dengue DENV and Chikungunya viruses CHIKV are primarily transmitted by two types of mosquitoes the Aedes aegypti and the Aedes albopictus Patients infected by DENV may experience dengue fever dengue hemorrhagic fever DHF and dengue shock syndrome DSS DHF and DSS could be fatal and are of particular public health concern in endemic regions of the U S Africa Asia ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  7. A mucosally targeted MERS CoV vaccine produced in plants

    SBC: Planet Biotechnology Incorporated            Topic: NIAID

    DESCRIPTION provided by applicant Middle East Respiratory Syndrome MERS coronavirus MERS CoV causes severe acute respiratory illness with a high fatality rate among reported cases MERS was first reported in but the virus has been circulating in camels which are thought to be an animal reservoir for at least years To date over MERS cases have been reported to the World Hea ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  8. Establishment of a patient like mouse models of soft tissue sarcoma sub types

    SBC: ANTICANCER, INC.            Topic: 100

    Project Summary Abstract Soft tissue sarcoma STS is a recalcitrant group of malignancies with over distinct histologic subtypes Patient derived mouse models of the representative STS subtypes that recapitulates disease progression and metastasis optimize the potential for individualizing STS therapy and for discovery of more effective therapeutics Our laboratory pioneered patient derived o ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  9. PHASER- Pluridirectional High energy Agile Scanning Electronic Radiotherapy

    SBC: TIBARAY, INC.            Topic: NCI

    PROJECT SUMMARY ABSTRACT The mission of TibaRay Inc is to develop and clinically translate next generation radiation therapy technologies for the treatment of cancer the single leading cause of death worldwide and increasing epidemically A major advance in radiation therapy RT that has increased its curative potential and decreased side effects is the ability to sculpt radiation doses exquis ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  10. Identification of macrocyclic molecules with antibacterial activity

    SBC: LINNAEUS BIOSCIENCE, INC.            Topic: NIAID

    Project Summary We have developed a new method to identify molecules with antibacterial activities that rapidly discriminates between different mechanisms of action MOA This approach bacterial cytological profiling BCP uses quantitative fluorescence microscopy to measure the effects of antibiotic treatment on individual cells Antibiotics that target different cellular pathways and differen ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
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