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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. A Rapid Paper Strip Nucleic Acid Test for the Point of Care Detection of Zika virus

    SBC: CROSSLIFE TECHNOLOGIES INC.            Topic: NIAID

    A Rapid Paper Strip Nucleic Acid Test for the Point of Care Detection of Zika virus CrossLife Technologies Inc Project Summary Abstract There are unmet needs for nucleic acids new diagnostics that can be applied at the point of care to detect Zika Virus ZIKV infections A highly sensitive simple paper strip molecular test that detects ZIKV at the point of care will be developed The target seq ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  2. Direct sequencing of serum antibodies after infection

    SBC: MAPP BIOPHARMACEUTICAL, INC.            Topic: NIAID

    Project Summary Monoclonal antibodies mAbs are a well validated drug platform with exquisite specificity diversity and potency They offer the lowest risk class of drug for development through licensure and offer great potential for addressing emerging and re emerging infectious diseases To be prepared as threats like Ebola EBOV Marburg MARV and Zika viruses continue to emerge or re em ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  3. Digital serology for parallel parasitic disease detection

    SBC: Serimmune            Topic: NIAID

    The proposed project aims to build a diagnostic test for chronic T cruzi infection and Chagas disease that not only improves testing performance but that can be readily integrated with similarly developed tests for most clinically important parasitoses Current assays for Chagas disease and other parasitic infections lack desired levels of specificity and require multiple independent assays an ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  4. Development of polyvalent inactivated rhinovirus vaccine

    SBC: MEISSA VACCINES INC            Topic: NIAID

    Human rhinovirus RV is the predominant etiological agent of the common cold and the leading cause of human infectious disease RV is more than a nuisance It is a major cause of community acquired pneumonia in children and adults in the United States and plays a major role in triggering exacerbations of both asthma and chronic obstructive pulmonary disease resulting in billions of dollars in me ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  5. Development of Novel Protease Activity-Based Diagnostics for the Rapid Identification of Candida Infections

    SBC: BIOSYNESIS, INC.            Topic: NIAID

    PROJECT SUMMARY ABSTRACT Members of the Candida genus of fungi form part of the normal human microbiota but are also opportunistic pathogens capable of causing serious mucosal and systemic infectionsCandida cells grow and divide in suspensionplanktonicculturesbut they also form resilient and drug resistant biofilmsorganizedtightlypacked communities of cells attached to a surfaceBiofilms colonize m ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  6. Deceased Donor Bone Marrow Salvage and Processing

    SBC: OSSIUM HEALTH INC            Topic: NIAID

    ABSTRACT This program aims to develop a method for banking clinical grade bone marrow from cadaveric donors that can be deployed nationally to ameliorate shortages provide bone marrow stockpiles as medical countermeasures for nuclear threats and support existing research approaches such as delayed immune tolerance induction and transfusion of HIV resistant stem cells We will adapt a method de ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  7. Nanowire Sensor based Assay for Detecting Dengue and Chikungunya Virus

    SBC: INNOSENSE CORPORATION            Topic: NIAID

    PROJECT SUMMARY The Dengue DENV and Chikungunya viruses CHIKV are primarily transmitted by two types of mosquitoes the Aedes aegypti and the Aedes albopictus Patients infected by DENV may experience dengue fever dengue hemorrhagic fever DHF and dengue shock syndrome DSS DHF and DSS could be fatal and are of particular public health concern in endemic regions of the U S Africa Asia ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  8. A mucosally targeted MERS CoV vaccine produced in plants

    SBC: Planet Biotechnology Incorporated            Topic: NIAID

    DESCRIPTION provided by applicant Middle East Respiratory Syndrome MERS coronavirus MERS CoV causes severe acute respiratory illness with a high fatality rate among reported cases MERS was first reported in but the virus has been circulating in camels which are thought to be an animal reservoir for at least years To date over MERS cases have been reported to the World Hea ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  9. Establishment of a patient like mouse models of soft tissue sarcoma sub types

    SBC: ANTICANCER, INC.            Topic: 100

    Project Summary Abstract Soft tissue sarcoma STS is a recalcitrant group of malignancies with over distinct histologic subtypes Patient derived mouse models of the representative STS subtypes that recapitulates disease progression and metastasis optimize the potential for individualizing STS therapy and for discovery of more effective therapeutics Our laboratory pioneered patient derived o ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  10. Detection of Methylation and Translocation Events by Novel Genomic Technologies

    SBC: BlueNovo Biosystems.com            Topic: NCI

    Detection of Methylation and Translocation Events by Novel Sequencing Technology ABSTRACTThe rapid development of DNA sequencing technologies advanced our understanding of the molecular basis of cancerHowevercancer genomics involves very complex molecular rearrangementssuch as translocationsrequiring the investigation of long DNA molecules with single nucleotide discriminationCurrent Next Generati ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
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