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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. A Novel Strategy to Identify Substances that Improve Mitochnodrial Fitness

    SBC: CYTEGEN CORP            Topic: NIA

    Project Summary Abstract Mitochondrial dysfunction causes mitochondrial diseases and is tightly linked to aging and neurodegenerative disorders such as Parkinsonandapos s and Alzheimerandapos s Recent discoveries support that mitochondrial dysfunction can be overcome to treat age related decline Cytegenandapos s hypothesis is that exercise induces the secretion of blood borne proteins that act ...

    STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  2. Biocatalytic production of precursors to lutein and zeaxanthin to address age related macular degeneration

    SBC: EscaZyme Biochemicals, LLC            Topic: N

    Project Summary Atrophic dry age related macular degeneration AMD is the leading cause of severe loss of vision for those over age Dietary supplements containing lutein and zeaxanthin are recommended by the NEI for those at risk of late AMD There has been a corresponding growth in demand for these two xanthophylls Lutein and zeaxanthin are currently sourced from marigolds grown mostl ...

    STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  3. Biological Treatment of Bacterial Keratitis

    SBC: AMEBAGONE INC            Topic: N

    Project Summary Abstract Bacterial keratitisBKis an infection of the cornea thatif left untreatedcan cause blindnessStaphylococcus aureusSaStreptococcus pneumoniaeSpand Pseudomonas aeruginosaPaare three major causes of BK in North AmericaSymptoms of BK include painrednessinflammationand opacity of the affected cornea and loss of visual acuityAmebaGone IncAGpartnered with UW Madison Department of O ...

    SBIR Phase II 2017 Department of Health and Human ServicesNational Institutes of Health
  4. Cost efficient optical guidance for spinal fusion using existing radiographic equipment and augmented reality display

    SBC: OnPoint Spine, Inc.            Topic: NIBIB

    ABSTRACT The technology that will be developed in this NIH SBIR Phase I and later Phase II proposal will provide novel systems for optical guidance of spinal surgery that will not use any of the expensive components currently used for surgical navigation intra operative CT or O arm imaging or robotics Instead the technology will leverage innovative new hardware such as optical head mounted d ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  5. Novel D Printed Architectures for Oral Long acting Drug Delivery Systems

    SBC: Lyndra Therapeutics, Inc.            Topic: NIBIB

    Novel D Printed Architectures for Oral Long Acting Drug Delivery Systems Project Summary Long acting oral LAO dosage forms may offer significant benefits for managing chronic medical conditions requiring long term and intensive medication regimens particularly those in which observed therapy would be practical and advantageous such as psychiatric disorders Poor patient adherence and persist ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  6. Improving access to vision correction for health disparity populations with the QuickSee: an accurate, low-cost, easy-to-use objective refractor

    SBC: PLENOPTIKA, INC.            Topic: NIBIB

    Summary The principal goal of this proposal is to increase the accuracy and precision of a low cost autorefraction device called the QuickSeein order to improve access to refractive eye care for underserved populationsPoor vision due to a lack of eyeglasses is highly prevalent in low resource settings throughout the world and significantly reduces quality of lifeeducationand productivityThe existi ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  7. Drug eluting Brachytherapy Implants for Chemo radiation Therapy

    SBC: TheraNano LLC            Topic: 102

    Prostate cancer PCa is the second leading cause of cancer death in American men with deaths and new cases estimated in the US in Radiation therapy is one of the standard therapies for high and intermediate risk patients and is a non surgical therapy option for low risk patients A combined chemo radiation therapy CRT approach has been shown in several trials to improve s ...

    STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  8. A novel immunotolerizing therapy for autoimmune vitiligo

    SBC: RADIKAL THERAPEUTICS, INC.            Topic: NIAMS

    Radikal TherapeuticsRTXis developing a pioneering therapy to restore immunotolerance and arrest progressive depigmentation in vitiligoAt our partnering institutionLoyola University Chicagoa variant to inducible Heat Shock Proteinwas developed with remarkable potential for the prevention and treatment of autoimmune vitiligoCarrying only a single amino acid modification to the proteinthis variant HS ...

    SBIR Phase II 2017 Department of Health and Human ServicesNational Institutes of Health
  9. Management of bioburden and tissue regeneration in diabetic wounds using engineered matrices

    SBC: GEL4MED, INC.            Topic: 300

    The goal of this Phase I SBIR proposal is to demonstrate the feasibility of an inherently broad spectrum antimicrobial tissue scaffolding matrix capable of eliminating infecting bacterial pathogens and improve wound closure in diabetics Delayed non healing diabetic wound is responsible for about annual non traumatic lower limb amputations in the US Microbial infections further complica ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  10. CONSTRUCTED ENVIRONMENTS FOR SUCCESSFULLY SUSTAINING ABSTINENCE THROUGH IMMERSIVE AND ON DEMAND TREATMENT

    SBC: CHARLES RIVER ANALYTICS, INC.            Topic: NIDA

    Charles River Analytics and our partners at Massachusetts General Hospital and Virtual Reality Medical Center propose to design and demonstrate Constructed Environments for Successfully Sustaining Abstinence Through Immersive and On Demand Treatment CESSATION We will build VR environments using our in house game engine and content cues that are diverse realistic and well placed bolstering ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
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