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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. New Technologies for Therapist Training and Patient Engagement in Behavioral Parent Training

    SBC: KOBAK, KENNETH A            Topic: 104

    Project Summary Abstract Behavioral parent trainingBPTis the gold standard treatment for disruptive behavior in preschool and elementary school age childrenDespite clear empirical evidence that it is effectiveadoption rates by practitioners remains woefully low due in part to a shortage of clinicians trained in BPTIn additioneven when BPT is administeredit is often done incorrectlyThe current stud ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  2. Stable Gene Transfer by RNA Delivery

    SBC: B-MoGen Biotechnologies Inc            Topic: NHLBI

    Abstract Non viral gene delivery is used in most biomedical laboratories for basic research and for many commercial and medical applications These include basic investigations into gene function modification of cells for the production of recombinant proteins and generation of genetically modified human cells for cancer therapy e g chimeric antigen receptor transgenic T cells However the d ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  3. Biomaterials for mRNA based cellular reprogramming

    SBC: STEM PHARM, INCORPORATED            Topic: 100

    Project Summary Abstract Induced pluripotent stem cells iPSCs hold great promise in the areas of disease modeling and regenerative medicine and as a result have unique commercial potential There are currently more than ongoing clinical trials in stem cell therapies including the first in human trial using human iPSC derived retinal pigment epithelial cells to treat ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  4. OpenBeds: Improving the Delivery of Care for Patients with Drug Addiction

    SBC: Openbeds Inc.            Topic: NIDA

    There is an urgent need for more effective mechanisms that leverage current technologies and best practices to both identify capacity and refer patients to drug treatment facilitiesThe applicant organizationOpenBeds Incis partnering with the non profit MESH Coalitionthree of the largest health care systems offering drug treatment in Indiana and the Indiana Division of Mental Health and AddictionDM ...

    SBIR Phase II 2017 Department of Health and Human ServicesNational Institutes of Health
  5. Increasing available choices for conjugate vaccine technology by producing carrier proteins in Scarab Genomics' reduced genome E coli strains

    SBC: SCARAB GENOMICS, LLC            Topic: NIAID

    Scarab Genomics goal is to commercialize carrier proteins for conjugate vaccine manufacture This proposal focuses on two bacterial carrier proteins that have been approved by the FDA and that are in use in pre clinical and clinical studies Exoprotein A EPA from Pseudomonas aeruginosa and Protein D PD from non typeable Haemophilus influenzae These proteins are difficult to make by the conve ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  6. Gaze Steered Microphone Array for Understanding Speech in Noisy Areas

    SBC: ADVANCED MEDICAL ELECTRONICS CORP            Topic: Y

    Project Summary Abstract Advanced Medical ElectronicsAMEproposes the development of a novel portable wireless hearing aid accessory that utilizes head pose and eye tracking of the hearing aid user to steer a microphone array in the direction of interestA common problem for hearing aid users is the difficulty of participating in conversations in a noisy environment such as at a workplace or restaur ...

    SBIR Phase II 2017 Department of Health and Human ServicesNational Institutes of Health
  7. Validation of Novel Therapeutic Approach for Cryptococcal Meningitis

    SBC: Minnetronix Medical, Inc.            Topic: NIAID

    Validation of a Novel Therapeutic Approach for Cryptococcal Meningitis PILadShivanand and McCabeAaron Project Summary When Cryptococcus is manifested as cryptococcal meningitisCMit creates a large burden of mortality and morbidity to the patient and is very difficult for the clinician to treatThere are now an estimatedUS cases andcases of CM worldwide annuallywith estimated mortality ofper yearCM ...

    STTR Phase II 2017 Department of Health and Human ServicesNational Institutes of Health
  8. Complete genome de novo assembly software for the emerging long read sequencing era

    SBC: DNASTAR, INC.            Topic: 400

    Despite the tremendous success of short read next generation sequencingNGStechnologiestheir inherent inability to establish long range connectivity makes fundamental tasks such as genome closurehaplotype phasing and alternatively spliced transcript characterization all but impossibleNowtwo long read sequencing providersPacific BiosciencesPacBioand Oxford Nanopore TechnologiesONTare producing data ...

    SBIR Phase II 2017 Department of Health and Human ServicesNational Institutes of Health
  9. Restimulating memory T cell responses in elderly by a novel, live influenza vaccine

    SBC: FLUGEN INC            Topic: NIAID

    Respiratory infections with influenza viruses cause severe morbidity and mortality in humans and animals worldwideImportantlyin humansthe majority of morbidity and mortality following flu infection is seen in older individualsrtyears oldYetclear understanding of how aging impacts on innate immune responsesand how to improve vaccine design in this age group is lackingRestimulating preexisting memor ...

    STTR Phase II 2017 Department of Health and Human ServicesNational Institutes of Health
  10. Non-pharmacological improvement of sleep structure in older people

    SBC: Mobile Sleep Technologies L.L.C            Topic: NIA

    ABSTRACT Poor sleep and memory problems are common in older adults and have considerable consequences including decreased productivitydeclines in cognitive abilitiesincreased rate of accidents and traffic fatalitiesand increased health care costsThese sleep and memory problems often occur in midlife and in older adultswhen aging is associated with insomniafragmentation of sleepand impairment of at ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
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