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Award Data

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The Award database is continually updated throughout the year. As a result, data for FY20 is not expected to be complete until September, 2021.

  1. Localized Statin Delivery for Prevention of Primary AV Fistula Failure

    SBC: AFFINITY THERAPEUTICS, LLC            Topic: NHLBI

    Abstract Summary Arteriovenous fistulas AVFs are the preferred vascular access mode for hemodialysis patients but of AVFs fail to mature and only of mature AVFs are patent after year Vascular access failure including AVFs results from neointimal hyperplasia and contributes to andgt $ billion USD annual costs from vascular access failure including of hemodialysis patient hosp ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  2. HLS Durable Implantable Non Obstructive Venous Assist Device NOVAD for Support of Cavopulmonary Fontan Circulation

    SBC: Perfusion Solutions, Inc.            Topic: NHLBI

    Project Summary Abstract The proposal addresses NHLBI Topic of Special Interest HLS Development of mechanical circulatory support devices for individuals with congenital heart disease and single ventricle physiology after Fontan surgical palliation The design was specifically stimulated by the requirements outlined to Perfusion Solutions Inc PSI by pediatric and congenital surgeon Dr P ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  3. Biomaterials for mRNA based cellular reprogramming

    SBC: Stem Pharm, Incorporated            Topic: 100

    Project Summary Abstract Induced pluripotent stem cells iPSCs hold great promise in the areas of disease modeling and regenerative medicine and as a result have unique commercial potential There are currently more than ongoing clinical trials in stem cell therapies including the first in human trial using human iPSC derived retinal pigment epithelial cells to treat ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  4. Peripheral nerve stimulation for amputee pain

    SBC: SPR THERAPEUTICS, INC.            Topic: 105

    AbstractThe goal of the presently proposed Commercialization Readiness PilotCRPProgram project is to prepare for commercialization of an implantable systemdeveloped in Phase IIthat is capable of delivering a novel peripheral nerve stimulationPNStherapy shown to be highly effective in treating intractable pain in a majority of amputees in previous studiesincluding Phase IApproximatelymillion indivi ...

    SBIR Phase II 2017 Department of Health and Human ServicesNational Institutes of Health
  5. Testing and Commercialization of a Superior Device to Maintain Perioperative Normothermia In Anesthetized Patients

    SBC: Mercury Biomed LLC            Topic: 400

    Project Summary Abstract This proposal presents Phase of the plan of Mercury Biomed LLC for commercializing the new and innovative WarmSmart technology to more effectively keep patients warm during anesthetized surgery The WarmSmart technology is based on IP licensed from the University of Texas at Austin who is the academic partner for this STTR proposal WarmSmart embodies several breakthr ...

    STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  6. HTS Assays for Targeting the cGAS STING Pathway in Autoimmune Diseases and Cancer

    SBC: Bellbrook Labs, LLC            Topic: 300

    SUMMARY Cytoplasmic nucleic acids alert the immune system to invading pathogens and trigger a robust type I interferon IFN response via activation of the STING stimulator of interferon genes receptor The sensor for cytoplasmic nucleic acids was recently discovered to be a cyclic GMP AMP synthase which produces a unique cyclic dinucleotide second messenger cGAMP that serves as an agonist fo ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  7. Software for OCT Analysis of Vascular Stents

    SBC: Dyad Medical, Inc.            Topic: NHLBI

    Software for OCT Analysis of Vascular Stents PI Ronny Shalev PhD Dyad Medical Summary Dyad Medical Inc will create intravascular OCT IVOCT software for clinical live time determination of stent apposition OCTivat live the live time OCT image visualization and analysis tool and for offline analysis of stent implantation OCTivat stent Every year s of thousands of patients in the US ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  8. High Fidelity Linear MicroVector to Clone Complex Problematic and Large DNAs

    SBC: VARIGEN BIOSCIENCES CORPORATION            Topic: 200

    The goal of this research is to dramatically improve the ability to clone and analyze large and unstable DNA fragments We propose to develop a novel linear cloning vector to maximize stability of cloned DNA in the bacterial host The vector will use the replication proteins of the phage Phi to achieve the highest accuracy of replication for all DNA inserts including AT rich repetitive or str ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  9. Automation of MicroC as a CDx for myeloma therapies

    SBC: Lynx Biosciences, Inc.            Topic: 102

    Multiple myeloma MM is a debilitating and currently incurable hematological malignancy While the median survival has increased to years MM patients ultimately relapse and become resistant to therapy Once they reach this stage it is often a trial and error process until an effective therapy can be found Furthermore the MM bone marrow tumor microenvironment plays a significant role in ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  10. IMMEDIATE FIT USING INNOVATIVE TECHNOLOGY PROSTHETIC SYSTEMS

    SBC: IFIT PROSTHETICS, LLC            Topic: N

    ABSTRACT The principal business interestiFIT Prosthetics LLCwith STTR fundingcreated a new transtibial prosthetic device and demonstrated its safetycomfortand functionIn contrast to conventionally made prosthetic limbsthe iFIT prosthesis is easily fit and aligned on the residual limb in a single sessionDue to its substantial adjustability and customized inner linerthe iFIT device is a comfortable ...

    SBIR Phase II 2017 Department of Health and Human ServicesNational Institutes of Health
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