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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Localized Statin Delivery for Prevention of Primary AV Fistula Failure

    SBC: AFFINITY THERAPEUTICS, LLC            Topic: NHLBI

    Abstract Summary Arteriovenous fistulas AVFs are the preferred vascular access mode for hemodialysis patients but of AVFs fail to mature and only of mature AVFs are patent after year Vascular access failure including AVFs results from neointimal hyperplasia and contributes to andgt $ billion USD annual costs from vascular access failure including of hemodialysis patient hosp ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  2. New Technologies for Therapist Training and Patient Engagement in Behavioral Parent Training

    SBC: KOBAK, KENNETH A            Topic: 104

    Project Summary Abstract Behavioral parent trainingBPTis the gold standard treatment for disruptive behavior in preschool and elementary school age childrenDespite clear empirical evidence that it is effectiveadoption rates by practitioners remains woefully low due in part to a shortage of clinicians trained in BPTIn additioneven when BPT is administeredit is often done incorrectlyThe current stud ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  3. HLS Durable Implantable Non Obstructive Venous Assist Device NOVAD for Support of Cavopulmonary Fontan Circulation

    SBC: Perfusion Solutions, Inc.            Topic: NHLBI

    Project Summary Abstract The proposal addresses NHLBI Topic of Special Interest HLS Development of mechanical circulatory support devices for individuals with congenital heart disease and single ventricle physiology after Fontan surgical palliation The design was specifically stimulated by the requirements outlined to Perfusion Solutions Inc PSI by pediatric and congenital surgeon Dr P ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  4. Biomaterials for mRNA based cellular reprogramming

    SBC: STEM PHARM, INCORPORATED            Topic: 100

    Project Summary Abstract Induced pluripotent stem cells iPSCs hold great promise in the areas of disease modeling and regenerative medicine and as a result have unique commercial potential There are currently more than ongoing clinical trials in stem cell therapies including the first in human trial using human iPSC derived retinal pigment epithelial cells to treat ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  5. OpenBeds: Improving the Delivery of Care for Patients with Drug Addiction

    SBC: Openbeds Inc.            Topic: NIDA

    There is an urgent need for more effective mechanisms that leverage current technologies and best practices to both identify capacity and refer patients to drug treatment facilitiesThe applicant organizationOpenBeds Incis partnering with the non profit MESH Coalitionthree of the largest health care systems offering drug treatment in Indiana and the Indiana Division of Mental Health and AddictionDM ...

    SBIR Phase II 2017 Department of Health and Human ServicesNational Institutes of Health
  6. Increasing available choices for conjugate vaccine technology by producing carrier proteins in Scarab Genomics' reduced genome E coli strains

    SBC: SCARAB GENOMICS, LLC            Topic: NIAID

    Scarab Genomics goal is to commercialize carrier proteins for conjugate vaccine manufacture This proposal focuses on two bacterial carrier proteins that have been approved by the FDA and that are in use in pre clinical and clinical studies Exoprotein A EPA from Pseudomonas aeruginosa and Protein D PD from non typeable Haemophilus influenzae These proteins are difficult to make by the conve ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  7. he 3D Platelet Bank: A Clinical-grade, Scalable, 3D Microbioreactor Bone Marrow Mimetic for Platelet Production

    SBC: KIYATEC, LLC            Topic: NIBIB

    Project Summary Abstract The transfusion of platelets is a major component of the treatment of cancer patients undergoing chemotherapy and or bone marrow transplantstrauma patientssepsisand battlefield injuriesHoweverdue to a complete reliance upon donors as the only current approved source of plateletsand the strictshort shelf life and storage conditions of donorderived plateletscurrent supplies ...

    SBIR Phase II 2017 Department of Health and Human ServicesNational Institutes of Health
  8. Peripheral nerve stimulation for amputee pain

    SBC: SPR THERAPEUTICS, INC.            Topic: 105

    AbstractThe goal of the presently proposed Commercialization Readiness PilotCRPProgram project is to prepare for commercialization of an implantable systemdeveloped in Phase IIthat is capable of delivering a novel peripheral nerve stimulationPNStherapy shown to be highly effective in treating intractable pain in a majority of amputees in previous studiesincluding Phase IApproximatelymillion indivi ...

    SBIR Phase II 2017 Department of Health and Human ServicesNational Institutes of Health
  9. Complete genome de novo assembly software for the emerging long read sequencing era

    SBC: DNASTAR, INC.            Topic: 400

    Despite the tremendous success of short read next generation sequencingNGStechnologiestheir inherent inability to establish long range connectivity makes fundamental tasks such as genome closurehaplotype phasing and alternatively spliced transcript characterization all but impossibleNowtwo long read sequencing providersPacific BiosciencesPacBioand Oxford Nanopore TechnologiesONTare producing data ...

    SBIR Phase II 2017 Department of Health and Human ServicesNational Institutes of Health
  10. Restimulating memory T cell responses in elderly by a novel, live influenza vaccine

    SBC: FLUGEN INC            Topic: NIAID

    Respiratory infections with influenza viruses cause severe morbidity and mortality in humans and animals worldwideImportantlyin humansthe majority of morbidity and mortality following flu infection is seen in older individualsrtyears oldYetclear understanding of how aging impacts on innate immune responsesand how to improve vaccine design in this age group is lackingRestimulating preexisting memor ...

    STTR Phase II 2017 Department of Health and Human ServicesNational Institutes of Health
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