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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until April, 2020.

  1. A low cost automated Gallium drug preparation device for diagnostic PET imaging

    SBC: Five Eleven Pharma Inc.            Topic: 102

    Abstract Five Eleven Pharma is developing a simple low cost device for automating the preparation of Ga labeled drugs at any site that is performing PET imaging The device is being developed to support the broader creation distribution research and use of Ga compounds in diagnostic PET imaging There has been a surge in the use of Ga based radiopharmaceuticals throughout the world in ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  2. Development of bioactive surface for pediatric hemodialysis catheters to prevent thrombogenic inflammatory and biofilm complications

    SBC: ENSION Inc            Topic: NICHD

    DESCRIPTION provided by applicant The most common hemodialysis catheter complications are thrombosis inflammation and biofilms Thrombotic deposition and inflammation have been shown to result in inadequate dialysis and lead to higher complication rates and increased mortality and can take many different forms including isolated clots thrombosis in vessels adjacent to the catheter tip or f ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  3. Advances in contact lens materials to extend wear time for a new standard in vision correction and future medical devices

    SBC: INDUSTRIAL SCIENCE & TECHNOLOGY NETWORK, INC.            Topic: M

    PROJECT SUMMARY Over the last two decades the commercialization of silicone hydrogel andquot SiHyandquot composite technologies has led to new soft CLs that are more breathable comfortable and affordable including in daily disposable versions which have considerably broadened the customer base especially among younger generations Despite these improvements the major persistent problem fa ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  4. INHIBITORS OF THE PHD ZINC FINGER TO TREAT ANEMIA

    SBC: Fox Chase Chemical Diversity Center, Inc.            Topic: NHLBI

    PROJECT SUMMARY ABSTRACT Anemia is common disease and is associated with many conditions including end stage renal disease Recombinant versions of Erythropoeitin EPO the key hormone that regulates red blood cell mass have been a mainstay of treatment for this condition The necessity of parenteral administration however has prompted the search for alternative methods for increasing red ce ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  5. Web based interactive program to prevent post partum depression in high risk women

    SBC: Fox Learning Systems, Inc.            Topic: 104

    Project Summary Postpartum depression PPD constitutes a general health problem occurring in of recently delivered mothers The impact of PPD is profound with considerable emotional pain for the mother as well as disturbances in infant development and later child adjustment Although the prevention of this disorder has garnered much attention few preventative interventions have demonstra ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  6. Pulmonary Assist Device for Destination Therapy

    SBC: Advanced Respiratory Technologies LLC            Topic: NHLBI

    Abstract The purpose of this proposal is to develop a highly biocompatible pulmonary assist device PAD to support patients with chronic lung disease for months to years Over million patients suffer from chronic lung disease in the US These patients suffer from a gradual decline in respiratory function coupled with acute exacerbations that lead to a transient but dangerous worsening of the ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  7. A novel D ultrasound platform using traditional D probes

    SBC: URSUS Medical LLC            Topic: 103

    PROJECT SUMMARY The goal of this project is to develop a low cost portable multipurpose D ultrasound imaging system based on traditional D ultrasound imaging technology The D imaging device will be capable of creating D images of superficial structures with high surface feature resolution and precision The D images will be achieved by correlating movements of the D probe measured by an ad ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  8. Development of novel research tools and a database for mapping human mitochondrial tRNA modifications by mass spectrometry

    SBC: Ribonova Inc.            Topic: R42

    Summary In this fast track Phase I II STTR project a novel mass spectrometry method and a matched reagent kit will be developed for mapping modified nucleotides in human mitochondrial transfer RNA mt tRNA including the most abundant modification pseudouridine which hitherto has proved to be a technical challenge because it is an isomer of uridine These new research tools will be harnessed t ...

    SBIR Phase II 2017 Department of Health and Human ServicesNational Institutes of Health
  9. DEVELOPMENT OF A NOVEL ANTIVIRAL TO TREAT AND PREVENT ACYCLOVIR RESISTANCE IN HUMAN OCULAR HERPES KERATITIS

    SBC: Fox Chase Chemical Diversity Center, Inc.            Topic: N

    ABSTRACT Infection of the eye by Herpes Simplex Virus HSV can result in Herpes Keratitis HK which is the leading cause of corneal blindness worldwide In the U S nearly individuals experience ocular herpes infections that are often recurrent and culminate in progressive corneal scarring and loss of vision The gold standard of care for HK is treatment with Acyclovir ACV that t ...

    STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  10. Tools for site specific antibody immobilization for immunoassays

    SBC: AlphaThera            Topic: N

    Antibodies most commonly Immunoglobulin Gs IgGs are widely used in research and diagnostic assays due to their wide array of targets high specificity and proven efficacy In many of these immunoassays e g ELISAandapos s biosensors etc antibodies must be immobilized onto surfaces The sensitivity stability and longevity of antibodies used in this context are highly dependent on orien ...

    STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health

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