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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Rapid Identification of Pathogenic Bacteria in Blood causing Sepsis

    SBC: ISENSE, LLC            Topic: NIAID

    Sepsis is the leading cause of deaths in US hospitals contributing to or causing of all US hospital deaths and is the most expensive condition treated in US hospitals costing more than $ billion annually More than million blood culture bottles are produced annually with a market size greater than $ B in the US and EU alone The two year phase II period spanned February to F ...

    SBIR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  2. Discovery of alpha4beta2 Nicotinic Receptor Antagonists as Alcohol Abuse Medications

    SBC: ASSUAGE PHARMACEUTICALS, INC.            Topic: NIAAA

    PROJECT SUMMARY Alcohol addiction and disorders associated to excessive alcohol use are a serious public health problem in the United States and in other parts of the world Current pharmacotherapies for the treatment of these disorders show limited efficacy Preclinical and clinical findings point to nicotinic acetylcholine receptors nAChRs as an alternative promising target for the developmen ...

    STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  3. Semantic Data Lake for Biomedical Research

    SBC: INFOTECH SOFT, INC.            Topic: 100

    Capitalizing on the transformative opportunities afforded by the extremely large and ever growing volume velocity and variety of biomedical data being continuously produced is a major challenge The development and increasingly widespread adoption of several new technologies including next generation genetic sequencing electronic health records and clinical trials systems and research data wa ...

    SBIR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  4. Product Development of Intensity Modulation for Bolus Electron Conformal Therapy

    SBC: Decimal, LLC            Topic: 102

    Project Summary Abstract Electron beam therapy EBT using MeV beams provides effective radiation treatment for superficial cancers depthandlt cm As many as of radiotherapy patients in USA annually are eligible for electron therapy for some portion of their treatment making it the second most used external beam modality As many as of these electron patients ...

    STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  5. Development of a LRP6 Monoclonal Antibody for Triple Negative Breast Cancer

    SBC: Stemsynergy Therapeutic            Topic: 102

    DESCRIPTION provided by applicant Triple negative breast cancer TNBC represents an aggressive tumor type with a distinct lack of effective treatment options Standard of care chemotherapy regimens typically produce a partial response followed by regression months to years later This Phase I application tests the hypothesis that in subtypes of TNBC activation of the WNT pathway represents t ...

    SBIR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  6. Point of care immunoassay for rapid diagnosis of tinea capitis

    SBC: DXDISCOVERY INC            Topic: NIBIB

    Tinea capitis scalp ringworm is a fungal dermatophyte infection of scalp hair follicles that afflicts of the U S pediatric population Tinea capitis is a major health care disparity because it occurs predominantly among individuals with a disadvantaged socioeconomic background and sub Saharan African descent Diagnosis of tinea capitis is currently dependent on culture and microscopy Both ...

    SBIR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  7. Simple, low cost assay for detection of HIV-1 antiretroviral resistance in resource-limited settings

    SBC: Discidium Biosciences, LLC            Topic: NIAID

    Antiretroviral therapy has become a reality in resource limited settings thanks to entities such as PEFAR and the Global Fund However contrary to the therapeutic choice flexibility in developed countries all patients go on reverse transcriptase inhibitor RTI based first line regimens with more expensive protease and integrase inhibitor based regimens being reserved as second line therapy for ...

    STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  8. Evaluation of SBP-101 for the Treatment of Acute Pancreatitis

    SBC: SUN BIOPHARMA, INC.            Topic: 300

    Project Summary Pancreatitis is a significant public health problem accounting for over $ Billion of health care costs annually Approximately one third of patients with acute pancreatitis will go on to have recurrent pancreatitis Of those about will progress to chronic pancreatitis a painful disease with an increased risk of both diabetes and pancreatic cancer More than of people w ...

    STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  9. Prevention of Proliferative Vitreoretinopathy by HC HA PTX

    SBC: BIOTISSUE HOLDINGS INC.            Topic: W

    Prevention of Proliferative Vitreoretinopathy by HC HA PTX Summary Proliferative vitreoretinopathy PVR is characterized by membranes that develop on the surface of the retina after rhegmatogenous retinal detachments RRD during which time RPE cells are dispersed into the vitreous cavity where they lose contact inhibition and are exposed to multiple growth factors and cytokines This patholog ...

    SBIR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health
  10. technologyIn vitro maturation of BMP responsive pancraeatic beta cell progenitors by oxygen modulation

    SBC: Ophysio Inc.            Topic: 200

    PROJECT SUMMARY Islet transplantation represents the current cell therapy standard for type diabetes T D However the gap between the availability of donor organs and the clinical demand for them calls for the development of alternative renewable sources of insulin producing cells In addition to this therapeutic need a steady supply of islets is also needed for research and drug discovery ...

    SBIR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health
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