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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Paired genomics and proteomics point-of-care platform for infectious diseases diagnostics

    SBC: Tasso, Inc            Topic: 400

    DESCRIPTION provided by applicant There is an urgent need for diagnostic technologies that can rapidly inform a healthcare professional on the appropriate management strategy for patients with infectious diseases Recent epidemics of flu and Ebola have crucially highlighted the importance for rapid detection solutions However point of care POC diagnostic devices are currently limited to a n ...

    SBIR Phase II 2015 Department of Health and Human ServicesNational Institutes of Health
  2. Combination Immunotherapy of a Novel Superagonist IL-15 Complex and Anti-CD20 Antibody for Indolent Non-Hodgkin Lymphoma

    SBC: Altor BioScience, LLC            Topic: 102

    DESCRIPTION provided by applicant Non Hodgkin lymphoma NHL is the most commonly diagnosed hematologic malignancy in the U S with over new cases and about deaths due to NHL expected in Over one third of all cases are slow growing or indolent NHL iNHL which affect older adults and typically present as advanced disease The initial treatment of iNHL consists of an anti CD ...

    SBIR Phase II 2015 Department of Health and Human ServicesNational Institutes of Health
  3. Radioactive Stents for Brachytherapy of Esophageal Cancers

    SBC: XL Sci Tech Inc            Topic: 102

    DESCRIPTION provided by applicant Current practice in the USA for inoperable esophageal cancer is a palliative treatment using metal stent for end stage cancer patients Outside the USA especially in far east countries including China and Korea there have been reported clinical benefits of attaching sealed sources such as prostate seeds to the outside of an esophageal stent Although sim ...

    SBIR Phase II 2015 Department of Health and Human ServicesNational Institutes of Health
  4. A DOPPLER SIMULATOR FOR VASCULAR ULTRASOUND TRAINING

    SBC: SHEEHAN MEDICAL LLC            Topic: NIBIB

    DESCRIPTION provided by applicant Doppler ultrasound is relied upon as the primary and often the only test used to diagnose vascular pathology Because variations in technical skill directly impact surgical referral decisions there is a strong clinical need to ensure that provides both attain and maintain skills in this procedure The problem we address is the lack of a quantitative or standar ...

    STTR Phase II 2015 Department of Health and Human ServicesNational Institutes of Health
  5. Therapeutic Neutralization of the Inflammasome After Spinal Cord Injury

    SBC: INFLAMACORE LIMITED LIABILITY COMPANY            Topic: 105

    DESCRIPTION provided by applicant Spinal cord injury SCI is a complex and devastating clinical condition mediated by proinflammatory cytokines that produce neuronal loss axonal destruction and demyelination during the secondary injury cascade There are currently no proven therapies targeting posttraumatic inflammation that have been shown to have clinical value We have previously shown th ...

    STTR Phase II 2015 Department of Health and Human ServicesNational Institutes of Health
  6. Continuous measurement of cell growth as an optimal tool in drug toxicity testing (Supplement)

    SBC: EnTox Sciences LLC            Topic: NCATS

    DESCRIPTION provided by applicant During the process of screening for drugs with therapeutic potential often times several candidates emerge as prime candidates with similar efficacy and the choice for a lead compound is difficult to make However peopleandapos s lives and billions of dollars may rest on the choice of which compound to bring to clinical investigation and trials Since any lev ...

    STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
  7. HARE: Action Recognition System for Behavioral Assessment Training, Data-sharing, and Early Markers Detection for Autism Spectrum Disorders.

    SBC: BSOLUTIONS, INC.            Topic: 103

    DESCRIPTION provided by applicant Early detection of autism leads to earlier treatment which is proven to have a major impact on outcomes In spite of recent advances in early Autism Spectrum Disorders ASD detection the average age of diagnosis in the US is still around five ASD diagnosis is currently performed via behavioral assessment which requires highly specialized training is not w ...

    SBIR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
  8. Novel selective alpha4beta2 nicotinic receptor antagonists for smoking cessation

    SBC: ASSUAGE PHARMACEUTICALS, INC.            Topic: NIDA

    DESCRIPTION provided by applicant Smoking remains the number one avoidable cause of death in the United States and costs the economy tens of billions of dollars every year Current therapies include nicotine replacement with a patch or gum inhibition of the dopamine system with bupropion and partial activation of the neuronal nicotinic acetylcholine receptor nAChR with varenicline Non ...

    SBIR Phase II 2015 Department of Health and Human ServicesNational Institutes of Health
  9. Optimization and Validation of an Indicator Cell Assay for Blood-Based Diagnosis of Alzheimers Disease

    SBC: PRECYTE INC            Topic: NIA

    DESCRIPTION provided by applicant We are developing the Indicator Cell Assay Platform iCAP a broadly applicable and inexpensive platform for blood based diagnostics that can be used for early detection of disease and as a companion diagnostic for drug development The iCAP uses cultured cells as biosensors capitalizing on the ability of cells to respond differently to signals present in th ...

    SBIR Phase II 2015 Department of Health and Human ServicesNational Institutes of Health
  10. Statistical Methods for Incomplete Data with Measurement Errors

    SBC: Data Numerica Institute, Inc.            Topic: 400

    DESCRIPTION provided by applicant Missing data censored data and surrogate markers are common incomplete data problems in biomedical data analysis In this project we are interested in statistical methods for experimental observational and genetic studies where there exist missing data measurement errors and surrogate markers Examples include health surveys containing non responders or m ...

    SBIR Phase II 2015 Department of Health and Human ServicesNational Institutes of Health
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