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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until April, 2020.

  1. Rapid Identification of Pathogenic Bacteria in Blood causing Sepsis

    SBC: ISENSE, LLC            Topic: NIAID

    Sepsis is the leading cause of deaths in US hospitals contributing to or causing of all US hospital deaths and is the most expensive condition treated in US hospitals costing more than $ billion annually More than million blood culture bottles are produced annually with a market size greater than $ B in the US and EU alone The two year phase II period spanned February to F ...

    SBIR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  2. Point of care immunoassay for rapid diagnosis of tinea capitis

    SBC: DxDiscovery Incorporated            Topic: NIBIB

    Tinea capitis scalp ringworm is a fungal dermatophyte infection of scalp hair follicles that afflicts of the U S pediatric population Tinea capitis is a major health care disparity because it occurs predominantly among individuals with a disadvantaged socioeconomic background and sub Saharan African descent Diagnosis of tinea capitis is currently dependent on culture and microscopy Both ...

    SBIR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  3. Prevention of Proliferative Vitreoretinopathy by HC HA PTX

    SBC: TISSUETECH, INC.            Topic: W

    Prevention of Proliferative Vitreoretinopathy by HC HA PTX Summary Proliferative vitreoretinopathy PVR is characterized by membranes that develop on the surface of the retina after rhegmatogenous retinal detachments RRD during which time RPE cells are dispersed into the vitreous cavity where they lose contact inhibition and are exposed to multiple growth factors and cytokines This patholog ...

    SBIR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health
  4. technologyIn vitro maturation of BMP responsive pancraeatic beta cell progenitors by oxygen modulation

    SBC: Ophysio Inc.            Topic: 200

    PROJECT SUMMARY Islet transplantation represents the current cell therapy standard for type diabetes T D However the gap between the availability of donor organs and the clinical demand for them calls for the development of alternative renewable sources of insulin producing cells In addition to this therapeutic need a steady supply of islets is also needed for research and drug discovery ...

    SBIR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health
  5. FIRST PERSON POINT OF VIEW AUGMENTED REALITY FOR MEDICAL TRAINING

    SBC: ARCHIE MD INC.            Topic: 400

    The physician to population ratio is beginning to plateau and is expected to decline right as the U S elderly and more medically needy population is on the rise Thus the physician workforce may not be able fulfill the U S populationandapos s demand In fact in the United States may face shortages of primary care physicians and medical specialists a total of too f ...

    SBIR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health
  6. Development of a Non adjuvanted VLP Vaccine against Stealth H N Influenza

    SBC: EPIVAX, INC.            Topic: NIAID

    DESCRIPTION provided by applicant The avian origin H N influenza virus that emerged in humans in China in presents a unique challenge to vaccine development because it is poorly immunogenic Neutralizing antibodies are not detected in acute phase infection Anti H antibody responses are significantly delayed and exhibit low avidity in comparison with antibodies generated following seas ...

    SBIR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  7. Multi Source E Beam kV X Ray Tube for Image Guided Radiotheraphy

    SBC: TELESECURITY SCIENCES, INC.            Topic: 102

    DESCRIPTION provided by applicant This project will develop a commercial product that will enable for the first time realtime tumor tracking during radiotherapy at an attractive price point and with minimal interference with standard clinical practice The key novel technology is an optimized multi source X ray tube with focal spots that is placed below the multi leaf collimator MLC of a r ...

    SBIR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health
  8. Mixed reality Simulation Training for Pediatric Airway Management Procedures

    SBC: ARCHIE MD INC.            Topic: NHLBI

    DESCRIPTION provided by applicant Pediatric and neonatal airway management skills are life saving difficult to master and used infrequently enough to make skill maintenance a serious challenge For example multiple studies have shown that pediatric and neonatal intubation procedures are often successful less than half of the time especially among residents Given the long skill acquisition ...

    SBIR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health
  9. A Fully Independent Real Time Treatment Verification System for Radiotherapy

    SBC: SUN NUCLEAR CORP.            Topic: 102

    DESCRIPTION provided by applicant Modern day radiotherapy has developed in complexity to the degree that significant treatment errors are both difficult to detect and difficut to completely avoid In the current day radiotherapy department it is common to have a large number of patients being treated with Intensity Modulated Radiotherapy IMRT techniques When treating patients with these tec ...

    SBIR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health
  10. Optical imaging of a CD based oral rinse with fluorescent detection to visualize oral cancer

    SBC: Vigilant Biosciences            Topic: NIDCR

    DESCRIPTION provided by applicant Oral squamous cell carcinomas including those of the mouth and oropharynx comprise more than of all cancers affecting these tissues Of all the major cancers oral cancer has one of the worst five year survival rates of Historically the death rate associated with this cancer is particularly high because it is discovered late stage III or IV oft ...

    SBIR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health

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