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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until April, 2020.

  1. Robotic Utility Mapping and Installation System (RUMI)

    SBC: Intelligent Automation, Inc.            Topic: 141FH3

    Today, urban underground spaces are shared by multiple utility companies for laying power lines, gas lines, water supply/sewage pipes, fiber-optic cables, etc. The recordings of such buried utilities are often erroneous, inadequate, or outdated (if they ever exist) due to insufficient surveying methodologies and as-built recording practices. Ability to accurately locate and provide awareness of bu ...

    SBIR Phase II 2019 Department of Transportation
  2. Reading Barcode signs to Support V21 Safety

    SBC: Intelligent Automation, Inc.            Topic: 180FH1

    Reading Barcode Signs to Support V21 Safety 3/20/2018 For this SBIR we will develop a machine vision system which uses onboard standard-resolution cameras in vehicles to identify and read barcode signs on the roadside. The proposed approach could provide a low-cost solution that make connected and automated vehicle (CAV) technology viable for rural areas with limited access to Information and ...

    SBIR Phase I 2018 Department of Transportation
  3. An Artificial Intelligence (AI) Traffic Data Analysis Tool for Advanced Freeway Traffic Management

    SBC: Intelligent Automation, Inc.            Topic: 180FH4

    An Artificial Intelligence (AI) Traffic Data Analysis Tool for Advanced Freeway Traffic Management 3/20/2018 Planned or unplanned traffic events cause various magnitude of traffic congestion and safety impact to road users. It was estimated that 60% of congestions are non-recurrent and 15% of incidents are secondary to the primal accidents. Thus local or regional Traffic Management Centers (T ...

    SBIR Phase I 2018 Department of Transportation
  4. Rapid Assessment of Air Void System in Fresh Concrete

    SBC: DYNAFLOW, INC            Topic: 171FH2

    Proposal title: Rapid Assessment of Air Void in System in Fresh Concrete Air void parameters such as specific surface (SS) and spacing factor (SF) are essential in evaluating Freeze-Thaw (F-T) durability in fresh concrete. We have demonstrated the feasibility and viability of using an acoustic method to measure in near real time air void distributions in fresh concrete, the proposed solution is b ...

    SBIR Phase II 2018 Department of Transportation
  5. A Systematic Medical Approach to Reward Transformation SMART for Brain Health in Opioid Use Disorder

    SBC: Versa Integrated Solutions, Inc.            Topic: 102

    Summary In recent years opioid use disorder OUD and deaths due to opiate overdose e g with heroin fentanyl oxycodone in suburban and rural non minority groups has created an urgency for approaches to stem this epidemic but the rise in OUD and opiate overdose deaths has occurred in inner cities at similar rates Heroin misuse and addiction are persistent problems in African American commu ...

    STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  6. Biocatalytic production of precursors to lutein and zeaxanthin to address age related macular degeneration

    SBC: EscaZyme Biochemicals, LLC            Topic: N

    Project Summary Atrophic dry age related macular degeneration AMD is the leading cause of severe loss of vision for those over age Dietary supplements containing lutein and zeaxanthin are recommended by the NEI for those at risk of late AMD There has been a corresponding growth in demand for these two xanthophylls Lutein and zeaxanthin are currently sourced from marigolds grown mostl ...

    STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  7. Novel Recombinant High Affinity Long and Dual Acting Equine CG Analogs for Improved and More Ethical Reproduction in Pigs and Cattle

    SBC: TROPHOGEN INC            Topic: NICHD

    As their first application for veterinary health the two PI s have already remarkably employed their novel patented superagonist and neoglycosylation technology to develop the first recombinant much more potent and long acting bovine FSH antagonists for improved cattle reproduction and a potential $ Million annual market This work was supported by a previous phase SBIR from FDA CVM whic ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  8. Novel Therapies for Duchenne Muscular Dystrophy

    SBC: MYOLOGICA, LLC            Topic: NIAMS

    Project Summary Myologica is a small business focused on developing therapeutics for neuromuscular diseases Started in collaboration with the University of Maryland Myologica maintains a vigorous in house pre clinical discovery program in Duchenne Muscular Dystrophy DMD while providing consultation and specialized neuromuscular function testing for non profit and corporate clients The object ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  9. Development and Commercialization of Predictive Biomarker Panel and In Office Kit for the Management of Diabetic Macular Edema

    SBC: OCULAR PROTEOMICS, LLC            Topic: N

    Abstract Diabetic Macular Edema DME is a vision threatening stage in Diabetic Retinopathy DR that can result in legal blindness The biochemical mechanisms that drive DME progression are not well understood and treatments address only portions of the disease pathology The available treatment options vary widely from injectable anti VEGF to injectable steroids to laser treatments and carry a ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  10. Development of a Novel Plasma Based Microsatellite Instability Diagnostic for Guiding Immunotherapy

    SBC: Personal Genome Diagnostics Inc.            Topic: 102

    Abstract Immune checkpoint inhibitors have recently emerged as a revolution in cancer care providing the potential for durable response and improved survival for numerous cancer patients across multiple cancer types However only of patients who are treated with checkpoint inhibitors have responded in most cancer types necessitating biomarker assays that can reliably and accurately ident ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health

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