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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until April, 2020.

  1. A Deep Learning Approach for Enhanced Discrimination of Nuclear Weapons Testing

    SBC: Array Information Technology, Inc            Topic: DTRA182005

    Seismic, hydro acoustic, and infrasonic (SHI) analyses possess many desirable properties, such as long-distance wave propagation and attributable spectral characteristics. They have been, by large, relegated to capturing massive explosions, earthquakes, bolides, and space-bound rocket launches. Although machine learning techniques have been employed on various military and commercial projects, rar ...

    SBIR Phase I 2019 Department of DefenseDefense Threat Reduction Agency
  2. Modeling of Chemical Hazards Dispersion in Lakes and Reservoirs in CONUS

    SBC: Maritime Planning Associates, Inc.            Topic: DTRA182004

    The objective of this study is to develop methods to adequately characterize the chemical and physical environments of lakes and reservoirs for the CONUS operational implementation within SHARC. Over the course of this project we will explore the novel and innovative integration of deep machine learning, data analytics, computational fluid mechanics and in-situ/overhead empirical data. Specificall ...

    SBIR Phase I 2019 Department of DefenseDefense Threat Reduction Agency
  3. Autonomous navigation through small, confined spaces

    SBC: ROBOTIC RESEARCH LLC            Topic: DTRA182002

    As more of our enemies expand the number and complexity of their underground facilities, the need to improve the tools that provide consistent situational awareness (SA) increases accordingly.For complex missions such as these, we require a family of systems (FoS) that have different capabilities, and can address various mission needs. Robotic Research proposes creating a unique, small platform (P ...

    SBIR Phase I 2019 Department of DefenseDefense Threat Reduction Agency
  4. Advanced Solutions for Radiation Susceptibility Analysis & Prediction

    SBC: DFR SOLUTIONS, LLC            Topic: DTRA162006

    The increasing complexity of devices, reduced budgets and accelerated program timelines, requires a new approach to predicting radiation of integrated circuit (IC) designs.Most approaches to date require gate level analysis and do not scale easily to device level calculations, leading to methods that are note practical under most program timeline and cost budgets.Previously, DfR Solutions has demo ...

    SBIR Phase II 2019 Department of DefenseDefense Threat Reduction Agency
  5. Automated Approaches to Analyze and Identify Dual Use Research of Concern from Scientific Publications

    SBC: Intelligent Automation, Inc.            Topic: DTRA172004

    The dual use potential of certain life sciences research has been recognized as an important biosecurity issue for a number of years. Current Dual Use Research of Concern (DURC) assessment procedures are pure manual work done by researchers/reviewers trained in the biosecurity domain. Therefore, an automated approach to analyze and identify DURC rapidly and reliably is urgently needed. To address ...

    SBIR Phase I 2018 Department of DefenseDefense Threat Reduction Agency
  6. A Systematic Medical Approach to Reward Transformation SMART for Brain Health in Opioid Use Disorder

    SBC: Versa Integrated Solutions, Inc.            Topic: 102

    Summary In recent years opioid use disorder OUD and deaths due to opiate overdose e g with heroin fentanyl oxycodone in suburban and rural non minority groups has created an urgency for approaches to stem this epidemic but the rise in OUD and opiate overdose deaths has occurred in inner cities at similar rates Heroin misuse and addiction are persistent problems in African American commu ...

    STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  7. Biocatalytic production of precursors to lutein and zeaxanthin to address age related macular degeneration

    SBC: EscaZyme Biochemicals, LLC            Topic: N

    Project Summary Atrophic dry age related macular degeneration AMD is the leading cause of severe loss of vision for those over age Dietary supplements containing lutein and zeaxanthin are recommended by the NEI for those at risk of late AMD There has been a corresponding growth in demand for these two xanthophylls Lutein and zeaxanthin are currently sourced from marigolds grown mostl ...

    STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  8. Novel Recombinant High Affinity Long and Dual Acting Equine CG Analogs for Improved and More Ethical Reproduction in Pigs and Cattle

    SBC: TROPHOGEN INC            Topic: NICHD

    As their first application for veterinary health the two PI s have already remarkably employed their novel patented superagonist and neoglycosylation technology to develop the first recombinant much more potent and long acting bovine FSH antagonists for improved cattle reproduction and a potential $ Million annual market This work was supported by a previous phase SBIR from FDA CVM whic ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  9. Novel Therapies for Duchenne Muscular Dystrophy

    SBC: MYOLOGICA, LLC            Topic: NIAMS

    Project Summary Myologica is a small business focused on developing therapeutics for neuromuscular diseases Started in collaboration with the University of Maryland Myologica maintains a vigorous in house pre clinical discovery program in Duchenne Muscular Dystrophy DMD while providing consultation and specialized neuromuscular function testing for non profit and corporate clients The object ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  10. Development and Commercialization of Predictive Biomarker Panel and In Office Kit for the Management of Diabetic Macular Edema

    SBC: OCULAR PROTEOMICS, LLC            Topic: N

    Abstract Diabetic Macular Edema DME is a vision threatening stage in Diabetic Retinopathy DR that can result in legal blindness The biochemical mechanisms that drive DME progression are not well understood and treatments address only portions of the disease pathology The available treatment options vary widely from injectable anti VEGF to injectable steroids to laser treatments and carry a ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health

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