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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until April, 2020.

  1. Deep Machine learning for risk Analysis and Prediction (D-MAP) in supply chains

    SBC: Intelligent Automation, Inc.            Topic: MDA16T002

    Globalization and digitization have been driving the recent economic growth at the expense of raising the risk level in the supply chain related to fraud, security, and safety, while current practice of supply chain management and risk assessment is lagging far behind. Therefore, commercial industries and government agencies are seeking advanced supply chain risk assessment solutions, which can ef ...

    STTR Phase II 2018 Department of DefenseMissile Defense Agency
  2. Highly specific HIV mRNA detection method with global subtype coverage to monitor latency reversal in patients

    SBC: Accelevir Diagnostics, LLC            Topic: NIAID

    Project Summary Abstract Human immunodeficiency virus type HIV is a retrovirus that infects CD T cells of the immune system If left untreated HIV infected individuals will progress to AIDS and may ultimately die as a result Combination antiretroviral therapy is extremely effective at stopping the replication of HIV in infected individuals Despite the success of this therapy at sup ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  3. Development and Commercialization of Predictive Biomarker Panel and In Office Kit for the Management of Diabetic Macular Edema

    SBC: OCULAR PROTEOMICS, LLC            Topic: N

    Abstract Diabetic Macular Edema DME is a vision threatening stage in Diabetic Retinopathy DR that can result in legal blindness The biochemical mechanisms that drive DME progression are not well understood and treatments address only portions of the disease pathology The available treatment options vary widely from injectable anti VEGF to injectable steroids to laser treatments and carry a ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  4. AiMNET: User-Configurable Autonomous Establishing and Management of Secure Networks

    SBC: Intelligent Automation, Inc.            Topic: MDA15011

    Intelligent Automation, Inc. (IAI) proposes to develop AiMNET, a User-Configurable Autonomous Establishing and Management of Secure Networks solution that automates network establishment and maintenance. The end result of this effort will significantly improve reliable network access to support automated and repeated simulation and tests, and reduce the cost and risks for networking.In Phase I, we ...

    SBIR Phase II 2017 Department of DefenseMissile Defense Agency
  5. Genetic Cytology for Ovarian and Endometrial Cancer Screening

    SBC: PAPGENE, INC.            Topic: 102

    DESCRIPTION provided by applicant In this Fast Track application a path to commercialization will be pursued for a breakthrough andquot genetic cytologyandquot test capable of detecting both ovarian and endometrial cancer from routinely collected Pap specimens In deference to the notable success of the Pap test in reducing deaths due to cervical cancer and in reference to the core enabling ...

    SBIR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health
  6. Development and testing of MRI mediated radiofrequency ablation system and probes

    SBC: Robin Medical, Inc.            Topic: NCI

    Project Summary Abstract Radiofrequency ablation RFA is a minimally invasive method used to treat solid tumors commonly primary liver cancers and metastases which are accessible percutaneously via a sharp needle Imaging guidance typically by ultrasound or CT is required for probe placement but these methods are incapable of monitoring the progress of the procedure Additional imaging sessi ...

    SBIR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health
  7. In Vivo Editing for Hemophilia Gene Therapy

    SBC: GENVEC, INC.            Topic: 100

    Project Summary The exceptional promise of gene therapy for hemophilia has been shown in recent studies that result in long term correction of factor IX deficiency via hepatic transduction with an adeno associated vector AAV In spite of this watershed event in the history of the gene therapy field there presently exist barriers to the fullest implementation of hemophilia gene therapy The li ...

    STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  8. A Systematic Medical Approach to Reward Transformation SMART for Brain Health in Opioid Use Disorder

    SBC: Versa Integrated Solutions, Inc.            Topic: 102

    Summary In recent years opioid use disorder OUD and deaths due to opiate overdose e g with heroin fentanyl oxycodone in suburban and rural non minority groups has created an urgency for approaches to stem this epidemic but the rise in OUD and opiate overdose deaths has occurred in inner cities at similar rates Heroin misuse and addiction are persistent problems in African American commu ...

    STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  9. Novel Single Chain Antibodies against MIF for Prostate Cancer Therapy

    SBC: IBEX BIOSCIENCES, LLC            Topic: 102

    With the help of the National Cancer Institute we at Ibex Biosciences propose the following Phase SBIR project to evaluate novel camelid VHH antibodies that target macrophage migration inhibitory factor MIF for the treatment of solid tumors MIF is known to play prominent roles in the development of cancer and its expression in humans has shown to correlate with prostate cancer severity ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  10. Novel DNA Launched Attenuated Vaccine for VEE Virus SBIR Phase II

    SBC: MEDIGEN, INC.            Topic: NIAID

    DESCRIPTION provided by applicant Venezuelan Equine Encephalitis virus VEEV is a life threatening NIH NIAID category B human pathogen and a potential bioterrorism threat Outbreaks of VEEV occur in Central America and have previously spread into the United States The potentially devastating effects of the virus reemergence in the U S demand an effective vaccine to protect population Curr ...

    SBIR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health

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