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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until April, 2020.

  1. TB Diagnostics at the Point of Care

    SBC: AKONNI BIOSYSTEMS INC.            Topic: NIBIB

    ABSTRACT This application to the Commercialization Readiness Pilot CRP Program is for commercialization assistance for our NIBIB Phase Project TB Diagnostics at the Point of Care The Phase Project is funded through an RFA that specifically addresses health disparities tuberculosis TB in the case of this project For every TB infected white person in the United States there are an es ...

    SBIR Phase II 2017 Department of Health and Human ServicesNational Institutes of Health
  2. Development and testing of MRI mediated radiofrequency ablation system and probes

    SBC: Robin Medical, Inc.            Topic: NCI

    Project Summary Abstract Radiofrequency ablation RFA is a minimally invasive method used to treat solid tumors commonly primary liver cancers and metastases which are accessible percutaneously via a sharp needle Imaging guidance typically by ultrasound or CT is required for probe placement but these methods are incapable of monitoring the progress of the procedure Additional imaging sessi ...

    SBIR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health
  3. Development of VLP vaccine for RSV

    SBC: SIGMOVIR BIOSYSTEMS, INC.            Topic: NIAID

    DESCRIPTION provided by applicant Respiratory syncytial virus RSV is a substantial threat to human health most severely affecting three large populations infants young children and the elderly Despite the significance of RSV disease in these different populations there are no vaccines available The goal of this Phase II STTR project is to continue preclinical testing of a novel RSV vac ...

    STTR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health
  4. Genetic Cytology for Ovarian and Endometrial Cancer Screening

    SBC: PAPGENE, INC.            Topic: 102

    DESCRIPTION provided by applicant In this Fast Track application a path to commercialization will be pursued for a breakthrough andquot genetic cytologyandquot test capable of detecting both ovarian and endometrial cancer from routinely collected Pap specimens In deference to the notable success of the Pap test in reducing deaths due to cervical cancer and in reference to the core enabling ...

    SBIR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health
  5. Technology to Select Candidates for Prophylactic Treatments to Prevent Sporadic Breast Cancers

    SBC: SILBIOTECH, INC.            Topic: 102

    PROJECT SUMMARY ABSTRACT This SBIR direct Phase II project is on developing a multimarker based technology for precisely selecting candidates for prophylactic treatments and preventing sporadic breast cancers The patient population addressed here for selecting candidates is among subjects diagnosed with proliferative precancerous breast tumors that include atypias papillomas sclerosing adenos ...

    SBIR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health
  6. Plant derived HIV neutralizing mAbs for passive immunotherapy in newborn macaques

    SBC: Plant Vax, Inc.            Topic: NIAID

    DESCRIPTION provided by applicant The identification of highly potent broadly neutralizing antibodies bnAbs against HIV and success in preventing SHIV infection following their passive administration have increased the likelihood that immunotherapeutic strategies can be adopted to prevent and treat HIV infection However while broad and potent neutralizing activity is an essential prer ...

    SBIR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health
  7. Novel Mucosal Adjuvant for an HIV DNA Vaccine

    SBC: PROFECTUS BIOSCIENCES, INC.            Topic: NIAID

    DESCRIPTION provided by applicant Our primary approach to develop an effective prophylactic vaccine against HIV utilizes a novel immunogen called the Full Length Single Chain FLSC that consists of gp derived from HIV genetically linked via a amino acid linker to the D D domains of human CD When rhesus macaques were inoculated with versions of FLSC that contain CD derived from rhes ...

    SBIR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health
  8. Multi Source E Beam kV X Ray Tube for Image Guided Radiotheraphy

    SBC: TELESECURITY SCIENCES, INC.            Topic: 102

    DESCRIPTION provided by applicant This project will develop a commercial product that will enable for the first time realtime tumor tracking during radiotherapy at an attractive price point and with minimal interference with standard clinical practice The key novel technology is an optimized multi source X ray tube with focal spots that is placed below the multi leaf collimator MLC of a r ...

    SBIR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health
  9. Innovative Image Guided Device for Beating Heart Mitral Valve Repair

    SBC: Harpoon Medical, Inc.            Topic: NHLBI

    DESCRIPTION provided by applicant Mitral valve disease is the most prevalent heart valve dysfunction in the U S affecting approximately of the total population and of the population over age With the aging population the occurrence of severe mitral regurgitation MR in the U S and Europe is projected to exceed M by and will present an increasing economic burden The Pro ...

    SBIR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health
  10. Indwelling Biosensor for real time chemotherapeutic blood level monitoring

    SBC: Diagnostic Biochips, Inc.            Topic: NHLBI

    DESCRIPTION provided by applicant The Specific Aim of this Phase II SBIR proposal is to develop a catheter based biosensor for monitoring chemotherapeutic blood levels during drug infusion This Phase II includes an IDE submission for clinical testing of our device The ability to monitor blood levels in real time will facilitate drug dosing within a narrow therapeutic range o minimize toxic si ...

    SBIR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health

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