List

For best search results, use the search terms first and then apply the filters
Reset

The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until April, 2020.

  1. Transwomen Connected a mobile app delivered HIV prevention program

    SBC: DFUSION INC.            Topic: 102

    ABSTRACT Transwomen Connected a mobile app delivered HIV prevention program During the past two decades the HIV epidemic has severely impacted transgender women in the U S Analysis of national HIV testing data found that transgender persons have the highest HIV incidence of any risk group and discrepancies between self reported prevalence and HIV testing data indicate that many HIV infect ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  2. A Systematic Medical Approach to Reward Transformation SMART for Brain Health in Opioid Use Disorder

    SBC: Versa Integrated Solutions, Inc.            Topic: 102

    Summary In recent years opioid use disorder OUD and deaths due to opiate overdose e g with heroin fentanyl oxycodone in suburban and rural non minority groups has created an urgency for approaches to stem this epidemic but the rise in OUD and opiate overdose deaths has occurred in inner cities at similar rates Heroin misuse and addiction are persistent problems in African American commu ...

    STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  3. Development of Pirenzepine for HIV SN

    SBC: WinSanTor, Inc.            Topic: 101

    PROJECT SUMMARY Over million people worldwide including million people in the USA are HIV positive HIV associated sensory neuropathy HIV SN is the most frequent neurological manifestation of HIV and is characterized as a distal symmetrical predominantly sensory polyneuropathy HIV SN may represent clinically indistinguishable neuropathies with distinct pathogenesis a distal axona ...

    STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  4. Biocatalytic production of precursors to lutein and zeaxanthin to address age related macular degeneration

    SBC: EscaZyme Biochemicals, LLC            Topic: N

    Project Summary Atrophic dry age related macular degeneration AMD is the leading cause of severe loss of vision for those over age Dietary supplements containing lutein and zeaxanthin are recommended by the NEI for those at risk of late AMD There has been a corresponding growth in demand for these two xanthophylls Lutein and zeaxanthin are currently sourced from marigolds grown mostl ...

    STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  5. Novel Recombinant High Affinity Long and Dual Acting Equine CG Analogs for Improved and More Ethical Reproduction in Pigs and Cattle

    SBC: TROPHOGEN INC            Topic: NICHD

    As their first application for veterinary health the two PI s have already remarkably employed their novel patented superagonist and neoglycosylation technology to develop the first recombinant much more potent and long acting bovine FSH antagonists for improved cattle reproduction and a potential $ Million annual market This work was supported by a previous phase SBIR from FDA CVM whic ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  6. Dihydroceramide Desaturase Inhibitors for Treatment of Diabetes and Other Metabolic Diseases

    SBC: Potrero Hill Therapeutics            Topic: 200

    Despite the current FDA approved therapies the prevalence of type diabetes T D and various other metabolic diseases is reaching epidemic proportions Globally million people have overt diabetes and the prevalence of impaired fasting glucose precursor to T D referred to as pre diabetes is of the US population Consequently T D and its frequent co morbidities high triglycerides ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  7. Autologous TGFB Modified CD Stem Cells for Repair of Diabetic Macular Edema and Macular Ischemia

    SBC: BETASTEM THERAPUETICS, INC.            Topic: N

    Autologous TGFB Modified CD Stem Cells for Repair of Diabetic Macular Edema and Macular Ischemia Retinal vascular diseases such as diabetic macular edema and macular ischemia remain a common cause of vision loss and blindness Diabetes can damage the small blood vessels in the retina causing them to leak and occlude resulting in vision loss Although tre ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  8. EZH inhibitors as endoprosthetic device coatings that induce osteogenesis and promote implant osseointegration

    SBC: Numerate, Inc.            Topic: NIAMS

    Project Summary Abstract With an aging population and increased life span the number of patients requiring reconstructive joint surgeries or joint replacements continues to increase Many patients undergoing arthroplasty procedures suffer from bone disorders such as osteoporosis severe arthrosis or osteopenia with a bony matrix that impedes firm anc ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  9. Novel Therapies for Duchenne Muscular Dystrophy

    SBC: MYOLOGICA, LLC            Topic: NIAMS

    Project Summary Myologica is a small business focused on developing therapeutics for neuromuscular diseases Started in collaboration with the University of Maryland Myologica maintains a vigorous in house pre clinical discovery program in Duchenne Muscular Dystrophy DMD while providing consultation and specialized neuromuscular function testing for non profit and corporate clients The object ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  10. Designed Antimicrobial Peptides for Treatment of Infectious Acne Vulgaris

    SBC: Riptide Bioscience, Inc.            Topic: NIAMS

    Public Abstract Acne vulgaris is a chronic inflammatory skin disorder affecting more than of all adolescents and young adults worldwide Acne causes a substantial cutaneous and psychologic disease burden often creating crippling effects in patients self esteem and socialization Acne management results in high monetary and physician use demands in the United States accounting for more than ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health

Agency Micro-sites

SBA logo
Department of Agriculture logo
Department of Commerce logo
Department of Defense logo
Department of Education logo
Department of Energy logo
Department of Health and Human Services logo
Department of Homeland Security logo
Department of Transportation logo
Environmental Protection Agency logo
National Aeronautics and Space Administration logo
National Science Foundation logo
US Flag An Official Website of the United States Government