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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Novel Targeted Therapy for Breast Cancer

    SBC: A&G PHARMACEUTICAL, INC.            Topic: NCI

    DESCRIPTION (provided by applicant): Breast cancer remains one of the top three cancers to affect and cause mortality in women. Major shortcomings with current treatment are the high level of side effects induced in patients and insufficient efficacy, particularly for patients with metastatic disease. Targeted cancer therapy is designed to treat only the cancer cells and minimize damage to healthy ...

    SBIR Phase II 2010 Department of Health and Human ServicesNational Institutes of Health
  2. A COMPANION DIAGNOSTIC FOR PROGNOSIS OF KIDNEY CANCER

    SBC: 20 20 Genesystems Inc            Topic: NCI

    This contract was awarded by the National Cancer Institute's Small Business Innovative Research (SBIR) and Small Business Technology Transfer (STTR) Program under the funding opportunity "Contract Topic: 277 Companion Diagnostics: Predictive and Prognostic Tests Enabling Personalized Medicine in Cancer Therapy."

    SBIR Phase I 2010 Department of Health and Human ServicesNational Institutes of Health
  3. PredicTOR: predicting patient response to mTOR pathway inhibitors prior to treatm

    SBC: 20 20 Genesystems Inc            Topic: NCI

    DESCRIPTION (provided by applicant): The promise of personalized medicine relies on the development of diagnostic tests to categorize patients within small cohorts who will benefit from specific treatments. 20/20 GeneSystems, Inc. (20/20) is a small business concern focused on the development of diagnostics for personalized medicine. Towards this end, 20/20 has developed, with the support of the N ...

    SBIR Phase II 2010 Department of Health and Human ServicesNational Institutes of Health
  4. TB Diagnostics at the Point of Care

    SBC: AKONNI BIOSYSTEMS INC            Topic: NIBIB

    DESCRIPTION (provided by applicant): Of all diseases, Tuberculosis (TB) represents one of, if not, the greatest health disparity between whites and minorities [1]. To be specific, for every TB-infected white person in the United States, there are an estimated 9 African-Americans, 8 Latinos, 6 Native Americans, 23 Asians, and 21 Native Hawaiian/Pacific Islanders with this disease [2]. Compounded wi ...

    SBIR Phase I 2010 Department of Health and Human ServicesNational Institutes of Health
  5. Development of a novel human rhinovirus vaccine

    SBC: BIOLOGICAL MIMETICS, INC.            Topic: NIAID

    DESCRIPTION (provided by applicant): Human Rhinoviruses (HRV) cause approximately one third of the 60 million cases of common cold each year in the US and therefore are one of the most economically important human diseases of developed countries. Although rhinoviruses are not generally considered killer viruses, more recent studies have shown that rhinoviruses are a significant source of hosp ...

    SBIR Phase I 2010 Department of Health and Human ServicesNational Institutes of Health
  6. New Needle for Two-Needle Hemodialysis

    SBC: BIOMEDICAL ENTERPRISES INC            Topic: NIDDK

    DESCRIPTION (provided by applicant): Studies performed with phase I SBIR grants 1R43DK55385-01A1 and 1 R43 DK59062-01A1 and phase II SBIR grants 2R44DK059062-02A1 and 5R44DK059062-04 have demonstrated the following: a) A new hemodialysis(HD) venous needle (NVN) with three jets is hemodynamically superior to the current venous needle (CVN) because it decreases the velocity of the vascular access ...

    SBIR Phase II 2010 Department of Health and Human ServicesNational Institutes of Health
  7. Device to Improve Treatment of Colorectal Cancer Using O2 Dependent Phosphorescen

    SBC: SURGISENSE CORPORATION            Topic: NCI

    DESCRIPTION (provided by applicant): Anastomotic failure is one of the most feared complications of gastrointestinal surgery due to the resultant morbidity and mortality. Failure of an anastomosis, or intestinal junction, can cause a spectrum of morbidities to the patient including local abscess formation - requiring procedural drainage, tumor recurrence, debilitating pain, dysfunctional defecatio ...

    SBIR Phase I 2010 Department of Health and Human ServicesNational Institutes of Health
  8. Point of Care Flu Drug Resistance Test

    SBC: CELLEX, INC.            Topic: NIAID

    DESCRIPTION (provided by applicant): The studies from our Phase I SBIR (AI082728-01) demonstrated that it is feasible to develop the proposed assay, a biochemiluminescence assay that uses a novel flu virus neuraminidase substrate, for sensitive detection of influenza virus drug resistance. The assay is now being used by a federal agency for monitoring influenza virus drug resistance during the on ...

    SBIR Phase II 2010 Department of Health and Human ServicesNational Institutes of Health
  9. Surface Enhanced Biocompatible Blood Oxygenators

    SBC: COMPACT MEMBRANE SYSTEMS, INC.            Topic: NHLBI

    DESCRIPTION (provided by applicant): Compact Membrane Systems, Inc. proposes to develop novel blood oxygenator membranes with enhanced blood biocompatibility. These will be used to enhance conventional cardio bypass surgery minimizing post operative effects. In addition, they will provide a key element for long term blood oxygenation associated with extracorporeal membrane oxygenation, acute respi ...

    SBIR Phase I 2010 Department of Health and Human ServicesNational Institutes of Health
  10. Supporting Teens with Autism on Relationships

    SBC: DANYA INTERNATIONAL, INC.            Topic: NIMH

    DESCRIPTION (provided by applicant): The purpose of this Phase II Small Business Innovation Research (SBIR) grant proposal is to outline the steps that Danya International, Inc. (Danya), will take to continue the development and evaluation of Supporting Teens with Autism on Relationships (STAR), formerly Relationship Education for Parents of Children with Autism (REPCA). STAR is an innovative, ski ...

    SBIR Phase II 2010 Department of Health and Human ServicesNational Institutes of Health
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