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Award Data
The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.
Download all SBIR.gov award data either with award abstracts (290MB)
or without award abstracts (65MB).
A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.
The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.
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Advanced Prediction of Emerging Respiratory Decline with the Linshom Continuous Predictive Respiratory Sensor (CPRS)
SBC: LINSHOM MEDICAL INC Topic: NHLBIAbstract: This Fast-track SBIR application will fund and enable a new approach to respiratory monitoring, continuous predictive respiratory monitoring (CPRM), that stands to reduce morbidity and mortality due to respiratory compromise, while reducing health care system costs. Current devices and systems (human and machine) for respiratory monitoring are responsive by sounding a warning alarm when ...
SBIR Phase II 2023 Department of Health and Human ServicesNational Institutes of Health -
Ultrasound Stimulated Chondrogenic Stem Cell Therapy for Osteoarthritis
SBC: LAB TO PHARMACY, LLC Topic: NIAMSAbstract Osteoarthritis (OA) is the most common degenerative disease in the musculoskeletal system. While it can affect any joint, hip, and knee, OA carries an enormous burden of pain and reduced mobility. Despite decades of research, there are currently no clinically effective treatments that can repair damaged cartilage or halt the progression of this disease. However, recent advances in tissue ...
SBIR Phase I 2023 Department of Health and Human ServicesNational Institutes of Health -
Anti-hIAPP for the preservation of pancreatic function in Type 2 Diabetes
SBC: CELDARA MEDICAL, LLC Topic: 200Project Summary According to the American Diabetes Association, Type 2 diabetes mellitus (T2D) affects at least 30 million Americans and is a major unmet public health concern with an annual cost in the United States of over $300 billion dollars. Additionally, nearly 25% of the U.S. population is already considered prediabetic, or at high risk of developing T2D. These individuals are characterized ...
SBIR Phase II 2023 Department of Health and Human ServicesNational Institutes of Health -
Non-invasively extendable megaprosthesis
SBC: Granite Medical, LLC Topic: NIAMSABSTRACT This project is the development of a non-invasively extending distal femur replacement (DFR) for children and adolescents subsequent to bone tumor resection. Each year in the US there are 200-250 malignant bone tumor diagnoses in the distal femurs of patients 15 years and younger. With advances in chemotherapy, limb salvage surgery utilizing a megaprosthesis has increasingly become the tr ...
SBIR Phase II 2023 Department of Health and Human ServicesNational Institutes of Health -
Inter-alpha Inhibitors in Experimental Necrotizing Enterocolitis
SBC: PROTHERA BIOLOGICS, INC. Topic: NICHDNecrotizing enterocolitis (NEC) is a devastating acute inflammatory condition of the gastrointestinal tract resulting in intestinal necrosis, systemic sepsis and multi-system organ failure found mostly in infants born prematurely. Despite modern medical advances in the past decade, the etiology remains elusive and morbidity and mortality are still unacceptably high. It has been concluded that the ...
SBIR Phase I 2023 Department of Health and Human ServicesNational Institutes of Health -
Digital Uroflowmetry for Office and Home
SBC: UROGENIE LLC Topic: 400Abstract Uroflowmetry is the most common urodynamic test performed by urologists to assess the function of the lower urinary tract. This simple non-invasive study measures urinary flow rates and when summarized graphically offers insights into various types of lower urinary tract symptoms. Current systems call upon a patient to void into a commode with a funnel to direct the flow of urine into a v ...
SBIR Phase II 2023 Department of Health and Human ServicesNational Institutes of Health -
PET Imaging to Evaluate a Novel Chemokine Antagonist to Protect Synapses in ADRD
SBC: CREATIVE BIO-PEPTIDES INC Topic: NIA7. Project Summary ADRD dementias account for up to 25% of all dementias in patients older than 65 years and there is strong evidence of co-morbid pathologies caused by (amyloid β (Aβ), tau and α-synuclein (αSyn). The degree of AD- related pathology in Lewy Body Dementias (LBD) is moderate or severe in 50% of PDD and more than 70% of DLB patients have concomitant AD-related pathology so that t ...
SBIR Phase I 2023 Department of Health and Human ServicesNational Institutes of Health -
A nanosized magnetic particle system for fast and efficient neuronal extracellular vesicle enrichment from plasma
SBC: CAPTIS DIAGNOSTICS Topic: RSUMMARY/Abstract Extracellular vesicles (EVs) are nanovesicles, which contain surface markers, and cell- and cell-state-specific cargo of their tissue (and cell) of origin, reflecting the tissue or cell’s physiological state. Most importantly, neuronal EVs can pass the blood-brain barrier (BBB) into blood circulation and provide a new approach of gaining direct access to brain pathogenic process ...
SBIR Phase I 2023 Department of Health and Human ServicesNational Institutes of Health -
Development of an Oscillated Insertion tool to Eliminate Surgically Induced Neurodegeneration for Optical Neuroimaging of Cognitive Aging and Dementia
SBC: ACTUATED MEDICAL, INC. Topic: NIAThis Phase I SBIR develops a system for gentle and accurate insertion of large optical neuroscience probes (e.g., GRIN lenses) to improve outcomes in aging research. Additionally, the project supports Qingguang Zhang. Ph.D. through the NIA Research and Entrepreneurial Development Immersion (REDI) program at a small business. Entrepreneurial development activities for his project will include proje ...
SBIR Phase I 2023 Department of Health and Human ServicesNational Institutes of Health -
Development of CM-CS1 CAR Treg to Treat Amyotrophic Lateral Sclerosis (ALS)
SBC: CELDARA MEDICAL, LLC Topic: 105SUMMARY Amyotrophic lateral sclerosis (ALS) patients develop fatal paralysis as a result of progressive motor neuron loss in the brain and spinal cord. There are more than 5,000 new cases of ALS per year in the United States, with typical age of onset between 40 and 70 years of age. While SOD1 is a cytoplasmic protein, misfolded SOD1 can be secreted and form extracellular oligomers and aggregates. ...
SBIR Phase I 2023 Department of Health and Human ServicesNational Institutes of Health