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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until April, 2020.

  1. Biocatalytic production of precursors to lutein and zeaxanthin to address age related macular degeneration

    SBC: EscaZyme Biochemicals, LLC            Topic: N

    Project Summary Atrophic dry age related macular degeneration AMD is the leading cause of severe loss of vision for those over age Dietary supplements containing lutein and zeaxanthin are recommended by the NEI for those at risk of late AMD There has been a corresponding growth in demand for these two xanthophylls Lutein and zeaxanthin are currently sourced from marigolds grown mostl ...

    STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  2. Active Power Exoskeleton Device for Spinal Cord Injury

    SBC: Abilitech Medical, Inc.            Topic: NICHD

    ! ABSTRACT Significance Spinal cord injuries SCI cause costly and morbid chronic conditions such as lack of voluntary movement increased chance of pressure sores problematic spasticity loss of bowel bladder and sexual function and more physical impairments which result in a lower quality of life and lack of independence Approximately people in the U S have SCI with new p ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  3. Vastly improved influenza diagnostics through the development of a handheld thermal contrast reader

    SBC: Vigilant Diagnostics, LLC            Topic: 600

    VIGILANT DIAGNOSTICS NIAID NIH STTR Phase I Application Vastly improved influenza diagnostics through the development of a portable thermal contrast reader PROJECT SUMMARY ABSTRACT Despite recent advances in rapid influenza diagnostic tests false negatives stemming from poor sensitivity contribute to nosocomial transmission and prevent thousands from receiving appropriate antiviral treatment A ...

    STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  4. Balloon Angioplasty Inflation Device

    SBC: Minnesota HealthSolutions Corporation            Topic: N

    Project Summary Abstract We propose the development of a novel balloon angioplasty inflation device for improving the safety and efficacy of balloon angioplasty Atherosclerosis is associated with coronary artery disease ischemic stroke and peripheral arterial disease Percutaneous balloon angioplasty often in conjunction with stent device deployment has been associated with prolonged survival ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  5. Automated Assistive Non Contact Sleep Quality Monitor for Individuals with Alzheimer Disease

    SBC: Innovative Design Labs Inc.            Topic: N

    Project Summary Abstract Proposed is an at home sleep monitoring system specifically designed for caregivers of persons with Alzheimerandapos s disease AD to remotely monitor sleep disturbances and trends Significance As of approximately million Americans live with AD and the number is expected to increase to million by costing the US $ trillion annually Individuals wit ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  6. A Passive Safety Monitoring System for Electric Powered Wheelchairs Operators with Alzheimer s disease AD and Cognitive Impairments

    SBC: Innovative Design Labs Inc.            Topic: N

    Project Summary Abstract Proposed is a passive safety monitoring system for wheelchair operators with or at risk of developing Alzheimerandapos s disease AD and cognitive impairments Significance Many older adults have chronic health conditions that limit mobility and thus wheelchair use is essential for maintaining independence However when an older wheelchair user exhibits signs of cogni ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  7. Social Assistive Robot Interface for People with Alzheimer s and Other Dementias to Aid in Care Management

    SBC: ADVANCED MEDICAL ELECTRONICS CORPORATION            Topic: NIA

    Project Summary Abstract Advanced Medical Electronics Corporation and our partners propose to develop a Socially Assistive Robot SAR system for persons with dementia PWD mild cognitive impairment Alzheimerandapos s disease or other dementias who are living in assisted living facilities The proposed system uses Augmented Intelligence AI to communicate with the PWD in natural language T ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  8. Environmental Imaging and Control for Exoskeletons to Improve Safety and Mobility

    SBC: Innovative Design Labs Inc.            Topic: N

    Innovative Design Labs IDL proposes to create a system to improve the mobility and control of exoskeletons Recent research has found that million Americans require wheelchairs and the number has been increasing annually by an average annual rate of per year While wheelchairs provide freedom allowing users to be independent as well as reducing dependence upon others wheelchair use i ...

    SBIR Phase II 2017 Department of Health and Human ServicesNational Institutes of Health
  9. INTRAVESICAL ONCOLYTIC THERAPY FOR BLADDER CANCER

    SBC: Vyriad, Inc.            Topic: 102

    PROJECT SUMMARY ABSTRACT Bladder cancer is a leading cause of death in the US and the most expensive cancer to treat Despite this there has been only one new bladder cancer therapy the checkpoint inhibitor atezoluzimab approved in the past years Oncolytic viruses viruses that selectively infect and kill cancer cells are a potent new class of immunotherapy that mediate anticancer activi ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  10. The Restful Jaw Device A New Way to Support and Protect the Jaw During Third Molar Extractions

    SBC: RESTFUL JAW COMPANY, LLC, THE            Topic: NIDCR

    Project Summary Dental procedures can cause jaw pain and discomfort from opening too long too wide or from having too much downward force placed on the patientandapos s jaw These painful symptoms can be short lived or become chronic leading to temporomandibular muscle and joint disorders TMJD Third molar extractions wisdom teeth have been associated with a incidence of post operative TM ...

    STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health

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