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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until April, 2020.

  1. Modeling of Chemical Hazards Dispersion in Lakes and Reservoirs in CONUS

    SBC: Maritime Planning Associates, Inc.            Topic: DTRA182004

    The objective of this study is to develop methods to adequately characterize the chemical and physical environments of lakes and reservoirs for the CONUS operational implementation within SHARC. Over the course of this project we will explore the novel and innovative integration of deep machine learning, data analytics, computational fluid mechanics and in-situ/overhead empirical data. Specificall ...

    SBIR Phase I 2019 Department of DefenseDefense Threat Reduction Agency
  2. A Preclinical Trial of Therapeutic Angiogenesis Plus Angioplasty and Stenting for Renal Vascular Disease

    SBC: Leflore Technologies LLC            Topic: 400

    Abstract Chronic kidney disease CKD is a progressive disorder affecting almost of the general population and this disease has shown a relentless growth over the past decades Patients with CKD have higher rates of hospitalization greater mortality shorter life expectancy and their healthcare costs are up to times more expensive than non CKD patients Thus treatments to slow halt ...

    STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  3. Biocatalytic production of precursors to lutein and zeaxanthin to address age related macular degeneration

    SBC: EscaZyme Biochemicals, LLC            Topic: N

    Project Summary Atrophic dry age related macular degeneration AMD is the leading cause of severe loss of vision for those over age Dietary supplements containing lutein and zeaxanthin are recommended by the NEI for those at risk of late AMD There has been a corresponding growth in demand for these two xanthophylls Lutein and zeaxanthin are currently sourced from marigolds grown mostl ...

    STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  4. Developing Testing and Validating a Wearable Alcohol Biosensor

    SBC: Clinitech, LLC            Topic: 450

    PROJECT SUMMARY This application for a Phase I SBIR award represents a collaboration between Clinitech LLC and McLean Hospital Harvard Medical School to develop a wearable biosensor for detecting alcohol in the interstitial fluid of humans who have consumed alcohol Excessive use of alcohol accounts for much of the public health burden related to alcohol use disorders including fetal ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  5. Novel Munition Technologies to Attack and Defeat Weapons of Mass Destruction (WMD)

    SBC: HYPERION TECHNOLOGY GROUP, INC.            Topic: DTRA143004

    Traditional weapon systems often fail to meet the requirements of close combat typical of the previously discussed engagement, where insurgents often blend in or store weapon amongst friendly or non-combatant forces, to shield them from precision strike munitions of a technologically superior force. This type of warfare has led to an increased focus on the use of less-lethal weapons, to reduce let ...

    SBIR Phase II 2017 Department of DefenseDefense Threat Reduction Agency
  6. Advanced Fast Shutter for Debris Mitigation

    SBC: HYPERION TECHNOLOGY GROUP, INC.            Topic: DTRA143007

    In an effort to development more robust optical system coatings DTRA, in collaboration with Sandia National Labs, is working to characterize the degradation of optical materials for space systems when exposed to high intensely EUV/ cold x-rays. The experiments utilizes the Double Eagle z-pinch facility which generates high current, high voltage arc pinch plasma to produce an intense EUV and cold x ...

    SBIR Phase II 2017 Department of DefenseDefense Threat Reduction Agency
  7. Development of a Non adjuvanted VLP Vaccine against Stealth H N Influenza

    SBC: EPIVAX, INC.            Topic: NIAID

    DESCRIPTION provided by applicant The avian origin H N influenza virus that emerged in humans in China in presents a unique challenge to vaccine development because it is poorly immunogenic Neutralizing antibodies are not detected in acute phase infection Anti H antibody responses are significantly delayed and exhibit low avidity in comparison with antibodies generated following seas ...

    SBIR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  8. Multi Source E Beam kV X Ray Tube for Image Guided Radiotheraphy

    SBC: TELESECURITY SCIENCES, INC.            Topic: 102

    DESCRIPTION provided by applicant This project will develop a commercial product that will enable for the first time realtime tumor tracking during radiotherapy at an attractive price point and with minimal interference with standard clinical practice The key novel technology is an optimized multi source X ray tube with focal spots that is placed below the multi leaf collimator MLC of a r ...

    SBIR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health
  9. Point of care immunoassay for rapid diagnosis of tinea capitis

    SBC: DxDiscovery Incorporated            Topic: NIBIB

    Tinea capitis scalp ringworm is a fungal dermatophyte infection of scalp hair follicles that afflicts of the U S pediatric population Tinea capitis is a major health care disparity because it occurs predominantly among individuals with a disadvantaged socioeconomic background and sub Saharan African descent Diagnosis of tinea capitis is currently dependent on culture and microscopy Both ...

    SBIR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  10. Advanced Electromagnetic Shutter for Hypervelocity Debris Mitigation

    SBC: HYPERION TECHNOLOGY GROUP, INC.            Topic: DTRA143007

    The proposed ultra-fast shutter achieves all design requirements for hypervelocity debris mitigation in the EUV cold x-ray Z-machine experiment using a high reliability magneforming shutter which has been field tested hundreds of times under conditions very similar to the Z-pinch machine. The proposed device is based upon the electromagnetic hypervelocity debris mitigation shutter put into operati ...

    SBIR Phase I 2016 Department of DefenseDefense Threat Reduction Agency

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