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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until April, 2020.

  1. A Preclinical Trial of Therapeutic Angiogenesis Plus Angioplasty and Stenting for Renal Vascular Disease

    SBC: Leflore Technologies LLC            Topic: 400

    Abstract Chronic kidney disease CKD is a progressive disorder affecting almost of the general population and this disease has shown a relentless growth over the past decades Patients with CKD have higher rates of hospitalization greater mortality shorter life expectancy and their healthcare costs are up to times more expensive than non CKD patients Thus treatments to slow halt ...

    STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  2. Biocatalytic production of precursors to lutein and zeaxanthin to address age related macular degeneration

    SBC: EscaZyme Biochemicals, LLC            Topic: N

    Project Summary Atrophic dry age related macular degeneration AMD is the leading cause of severe loss of vision for those over age Dietary supplements containing lutein and zeaxanthin are recommended by the NEI for those at risk of late AMD There has been a corresponding growth in demand for these two xanthophylls Lutein and zeaxanthin are currently sourced from marigolds grown mostl ...

    STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  3. Developing Testing and Validating a Wearable Alcohol Biosensor

    SBC: Clinitech, LLC            Topic: 450

    PROJECT SUMMARY This application for a Phase I SBIR award represents a collaboration between Clinitech LLC and McLean Hospital Harvard Medical School to develop a wearable biosensor for detecting alcohol in the interstitial fluid of humans who have consumed alcohol Excessive use of alcohol accounts for much of the public health burden related to alcohol use disorders including fetal ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  4. Development of a Non adjuvanted VLP Vaccine against Stealth H N Influenza

    SBC: EPIVAX, INC.            Topic: NIAID

    DESCRIPTION provided by applicant The avian origin H N influenza virus that emerged in humans in China in presents a unique challenge to vaccine development because it is poorly immunogenic Neutralizing antibodies are not detected in acute phase infection Anti H antibody responses are significantly delayed and exhibit low avidity in comparison with antibodies generated following seas ...

    SBIR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  5. Multi Source E Beam kV X Ray Tube for Image Guided Radiotheraphy

    SBC: TELESECURITY SCIENCES, INC.            Topic: 102

    DESCRIPTION provided by applicant This project will develop a commercial product that will enable for the first time realtime tumor tracking during radiotherapy at an attractive price point and with minimal interference with standard clinical practice The key novel technology is an optimized multi source X ray tube with focal spots that is placed below the multi leaf collimator MLC of a r ...

    SBIR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health
  6. Point of care immunoassay for rapid diagnosis of tinea capitis

    SBC: DxDiscovery Incorporated            Topic: NIBIB

    Tinea capitis scalp ringworm is a fungal dermatophyte infection of scalp hair follicles that afflicts of the U S pediatric population Tinea capitis is a major health care disparity because it occurs predominantly among individuals with a disadvantaged socioeconomic background and sub Saharan African descent Diagnosis of tinea capitis is currently dependent on culture and microscopy Both ...

    SBIR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  7. Multi-Object Payload Deployment

    SBC: SYSTEMS ENGINEERING ASSOCIATES CORPORATION            Topic: MDA15018

    Technological advances have facilitated weapons systems capable of simultaneously supporting multiple missions leading to cost efficiencies and greater operational flexibility.Future systems capable of deploying multiple payloads from a single missile will enable various targets to be attacked with a single launch allowing more efficient use of limited and valuable resources.For such a system to w ...

    SBIR Phase I 2016 Department of DefenseMissile Defense Agency
  8. Water-washout tooling for improved high- to very-high-temperature manufacturing of SM-3 TSRM composite motor cases

    SBC: Nevada Composites, Inc.            Topic: MDA14002

    Nevada Composites has developed Green-AeroSM tooling, lightweight ceramic tooling that is stable under high pressure and long-duration cure cycles and can be washed out with water after cures to the highest resin-matrix-composite cure temperatures. The proposed Phase II program would build on the successful work in Phase I toward creation of a washout mandrel for the upper stage rocket motor of a ...

    SBIR Phase II 2016 Department of DefenseMissile Defense Agency
  9. Imaging Instrumentation System

    SBC: DBV TECHNOLOGY, LLC            Topic: N08199

    There are two main objectives of the follow-on Phase II for Small Business Innovation Research Topic N08-199.First is to deliver a portable Splash Impact Measurement System (SIMS) with capablility of mapping the debris field surrounding an engagement event in broad ocean areas.This mapping will provide the precise location and time of all objects impacting the sea surface.The second objective is t ...

    SBIR Phase II 2016 Department of DefenseMissile Defense Agency
  10. IGF OT IGF A STAGE BASED MOBILE INTERVENTION FOR SUBSTANCE USE DISORDERS IN PRIMARY CARE N DA POP SEPTEMBER FEBRUARY BASE AWARD

    SBC: Pro-Change Behavior Systems Inc            Topic: NIDA

    Not Available

    SBIR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health

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